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Posts tagged #polyA

A image saying "I want you to kiss you lovers" with a hand pointing at you the reader

A image saying "I want you to kiss you lovers" with a hand pointing at you the reader

Oh yeah it's valentine's day, here goes for all the #polyA peeps
#valentine #polyamory

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Je pense qu'il me faudrait au moins 2 hommes et 1 femmes dans ma vie pour me combler 💕
#polyA

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#polya

Kiffer voir sa chérie s'amuser à une soirée avec sa femme, pendant que je fais moi-même une soirée avec mon chéri. Quelle douceur 😊✨️

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Pure love
#ocs #polyA

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I am #polyA . And I don't care at all about those who are bothered by it, or those who tell me it's not normal.
I love you my 3 loves
#polyamorousrelationship

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Comment what u'd like to do with me.. I'm so horny rn 🤭
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#puppy #pup #ftm #pussyboy #play #gayporn #enm #polyA #fuckme #puppyplaycommunity

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« Je pense que l’amour ne survit que lorsqu’il sait qu’il a le droit d’aller et venir sans que personne se pète la tête sur les murs. »

Catherine Dorin, Les luttes fécondes

#polyam #polya #polyamour

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A spatial long-read approach at near-single-cell resolution reveals developmental regulation of splicing and polyadenylation sites in distinct cortical layers and cell types. #LongReads #SingleCell #Spatialtranscriptomics #IsoSeq #PolyA @natcomms.nature.com
www.nature.com/articles/s41...

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Slumber Party GIF ALT: Slumber Party GIF

Not me suggesting that you throw a slumber party with all of your partners so we can have a bj competition on you.

#nsfw #enm #polya

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Deux chats se promènent ensemble.

Deux chats se promènent ensemble.

Pareil pour moi. Mes partenaires étaient abandonnés, je les ai adoptés. On dort à trois toutes les nuits, c’est beau. #PolyA

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Toujours cette envie dans ma tête de rencontrer d’autres femmes, de jouer de la séduction, de sentir le désir monter, de goûter d’autres chemins du plaisirs, d’autres langages, d’autres saveurs.
#JeudiConfession
#PolyA

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Benchmarking of methods that identify alternative polyadenylation events in single-/multiple-polyadenylation site genes. #PolyA #MethodBenchmarking #Genomics #NARgenomicsAndBioinformatics
academic.oup.com/nargab/artic...

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Other puppies in Switzerland? 🐾
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#puppy #play #puppyplay #hood #pup #shoes #kink #gay #gaykink #gaypup #chains #bedtime #kinkypup #bdsm #playful #queer #harness #polya #puplogych

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Live now with @heartmyarc.bsky.social and @fitnessnerd6.bsky.social 🩷

#polya #threesome #couple #cute #threeway #polyamorous #chaturbate #fansly #joystick

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Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 1/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 1/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 2/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 2/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 3/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 3/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 4/4

Photo de l'article "Le polyamour, vivre des amours plurielles avec éthique ?" 4/4

Article : "Le polyamour, vivre des amours plurielles avec éthique ?" paru dans Blandice 31 (Avril 2025)

Enfin un article qui traite du PolyA sans sous-entendus récurrents sur "le ton de l'humour" que l'on peut régulièrement retrouver sur les réseaux sociaux.

Intéééreeessaant 🎶

#polyamour #polya

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#mRNA #vaccine stability and efficacy depends on its #polyA tail and is boosted by re-adenylation in #macrophages by my favourite enzyme TENT5A - in @nature.com by @pakraw.bsky.social and Seweryn Mroczek, Lab of RNA Biology - ERA Chairs Group @iimcb.bsky.social led by @andrzejdziembowski.bsky.social

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We then detected the same #polyA elongation pattern in #macrophages - both those sorted from muscles surrounding injection sites and in the in vitro models (mouse bone marrow-derived macrophages (mBMDMs) and human monocyte-derived macrophages (hMDMs)). (8/n)

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Crucially, when examining #mRNA #vaccines at injection sites in #mice, we discovered an unexpected phenomenon: #polyA tails were extended from ~100 to ~200 nucleotides - contradicting the expected degradation pattern observed in standard cell lines. (7/n) #mRNAStability

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The #Moderna #mRNA-1273 vaccine possesses a ~100 nucleotide #polyA tail terminated with a distinctive pentamer (mΨCmΨAG), which served as a critical molecular marker, facilitating differentiation between processed and unprocessed tails. (5/n)

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To overcome this obstacle, I developed a Dynamic Time Warping approach to detect and analyze vaccine molecules using #DRS with high fidelity, enabling precise characterization of #polyA tails from #therapeutic #mRNAs. (4/n)

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We employed @nanoporetech.com
#direct #RNA #sequencing (DRS) to characterize individual therapeutic mRNA molecules - specifically focusing on #polyA #tail dynamics. However, #methylpseudouridine (mΨ) modifications in therapeutic mRNAs create significant analytical challenges. (3/n)

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The latest achievement from the Dziembowski Lab @IIMCB now published at @naturecomms.bsky.social. Ninetails is a #neural-network based tool using
@nanoporetech.com #directRNA data to identify and quantify non-adenosines in #mRNA #polyA tails.
Huge congrats to Natalia!

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Direct profiling of non-adenosines in poly(A) tails of endogenous and therapeutic mRNAs with Ninetails - Nature Communications Ninetails, a neural network that uses Nanopore Direct RNA sequencing data to identify non-A residues in mRNA poly(A) tails is presented. Particularly non-A of therapeutic, mitochondrial, and TENT5A/C ...

Congratulations to all authors, especially Natalia! Great work!
#ninetails #nanopore #polyA #mRNA #vaccines

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Chromatin retained MUSHER lncRNA integrates ABA and DOG1 signalling pathways to enhance Arabidopsis seeds dormancy Many plant lncRNAs regulate gene expression by binding to chromatin, but how they are retained at the target loci is unclear. We identify a new, chromatin-localized lncRNA - MUSHER , which activates t...

A very insightful work into #lncRNA parallel functions, U1-dependent #chromatin association, and alternative #polyA site selection.

I am delighted to be part of this work led by Szymon Swiezewski and Sebastian Sacharowski.

⚠️ Preprint
www.biorxiv.org/content/10.1...

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Poly-ish Movie Reviews - Episode 51 - 5 to 7 5 to 7 (2014) www.imdb.com/title/tt2486678/ - Internet Movie Data Base www.tvguide.com/movies/5-to-7/2030198579/ - Where To Stream https://amzn.to/4jMv5Em - Amazon It's so much worse when they manag...

It's been a while, but I'm trying to get back into a routine with the Poly-ish Movie Review podcast, so a new episode is out! www.polyishmoviereviews.com/show-notes/e...
#polyamory #polyamorous #poly #polya #polyam #non-monogamy #nonmonogamy #EthicalNonMonogamy #ENM #ConsensualNonMonogamy #CNM

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Ça a pas pécho à la Saint-Valentin ici ou quoi ?
(lol je guéris actuellement d'une relation, calmos)

Si t'a la ref de l'image j'suis désolée pour toi même si tu fera partie des rares ayant la ref et ça ça slay !

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#Meme #MemeFR #MemeFrancais #Polyamorous #PolyA #memecredi

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Le principal problème lorsque l'on dans un #couplelibre (pareil pour #libertinage ou #polyA), c'est de trouver des partenaires.

Tout particulièrement si on vit dans une région rurale et plutôt conservatrice...

Encore plus quand ta dynamique de couple est mal comprise !

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