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2/ 🔍 We investigated the proinflammatory response to TNF in primary human cells using #scRNA and #scATAC sequencing and fluorescence microscopy. We identified ~1,500 TNF-regulated genes (TRGs) that often clustered in the genome and exhibited induced co-expression.

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Multiscale footprints reveal the organization of cis-regulatory elements Nature - We developed PRINT, a computational method that identifies footprints of DNA–protein interactions from bulk and single-cell chromatin accessibility data across multiple scales of...

If you are looking for ways to escape the news. This new computational method looks very interesting! #scATAC #footprints

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