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Diverse database and machine learning model to narrow the generalization gap in RNA structure prediction Length matters—secondary structures of long, diverse RNAs in RNAndria and deep learning model eFold improve prediction accuracy.

From #AAAS 's #scienceadvances journal | Diverse #database and machine learning model to narrow the generalization gap in #RNA structure prediction | #Bioinformatics #ML #Genomics #OpenScience #StructurePrediction #RNAStructurePrediction | 🧬 🖥️ 🧪 🔓
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www.science.org/doi/10.1126/...

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Major modes of behavior within low-pLDDT regions were identified through a survey of human proteome predictions provided by the AlphaFold Protein Structure Database #AlphaFold2 #StructurePrediction #ConditionalFolding doi.org/10.1107/S205...

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Models generated by Alphafold2 and AlphaFold3 We provide all the PDB files that we analyzed for the article "Challenges in predicting PROTAC-mediated Protein-Protein Interfaces with AlphaFold" Change from version 2: removed case 2wdt from the ligand-mediated cases.  

🧾 All structural models and evaluation data from this study are openly available via Zenodo, supporting reproducibility and further benchmarking: https://zenodo.org/records/14810843 

#OpenScience #StructurePrediction

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Original post on mastodon.social

6-Mar-2025
A new algorithm sheds light on ‘disordered’ #proteins

The #IntrinsicallyDisorderedProteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making #structurePrediction particularly challenging. These proteins although exhibit […]

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Open Postdoc Position at the schwede lab, Biozentrum Basel.

Open Postdoc Position at the schwede lab, Biozentrum Basel.

🧪🧬🔬 Postdoc in Computational Structural Biology at the @biozentrum.unibas.ch & @sib.swiss in Basel, Switzerland.

www.biozentrum.unibas.ch/open-positio...

The position is initially funded for 3 years, possibility to start immediately.

#StructurePrediction, #Bioinformatics, #Uniprot3D, #AI

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🎁 Our February Issue is online🎁

📘“In the Limelight” issue focusing on Structural Bioinformatics. Don't miss the new Review Articles, as introduced by Guest Editors @cmslnsoares and Diana Lousa

🔓https://buff.ly/4aKTjeg

#StructuralBioinformatics #StructurePrediction

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🎁 The February issue of FEBS Open Bio is now online!

💡 This “In the Limelight” issue focuses on Structural Bioinformatics. Don't miss the new Review Articles, as introduced by Guest Editors Claudio M. Soares and Diana Lousa!

🔓 buff.ly/4aKTjeg

#StructuralBioinformatics #StructurePrediction

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RNA-Puzzles Round V: blind predictions of 23 RNA structures - Nature Methods The results of the Fifth RNA-Puzzles contest highlights advances in RNA three-dimensional structure prediction and uncovers new insights into RNA folding and structure.

RNA-Puzzles Round V: blind predictions of 23 RNA structures

Cool to see how #RNA #structureprediction is coming along!

www.nature.com/articles/s41...

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