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Upregulation of antioxidant genes in antimony-resistant Leishmania tropica clinical isolates - Molecular Biology Reports Background Increasing resistance to antimonial drugs has become a significant challenge in effective treatment in endemic regions of leishmaniasis. Antioxidant defense plays a crucial role in antimony...

The upregulation of antioxidant genes could probably contribute to natural antimony resistance in Leishmania tropica isolates.

doi.org/10.1007/s110...

#Leishmania #antioxidantgenes #antimonyresistance #drugresistance #Leishmaniatropica #redox #antioxidant #trypanothione #tryparedoxin #peroxidase

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