City University Research Sheds Light on 'Asian Flush' Mechanism for Heart Attack Treatments #Hong_Kong #HEART_ATTACK #Asian_Flush #ALDH2
Latest posts tagged with #ALDH2 on Bluesky
City University Research Sheds Light on 'Asian Flush' Mechanism for Heart Attack Treatments #Hong_Kong #HEART_ATTACK #Asian_Flush #ALDH2
This study highlights #ALDH2 inhibition as a potent synthetic lethal strategy for APC-deficient #ColorectalCancer, inducing tumor cell death through the ROS-dependent activation of the ASK1/JNK apoptotic pathway.
#OpenAccess: doi.org/10.1016/j.ge...
New publication alert π’
This new review explores how alcohol, genetics, aging, immunity, and the gut microbiome converge to shape disease risk across the lifespan.
Read the research: π zurl.co/AIrI4
#AlcoholResearch #GutMicrobiome #BrainHealth #IntegrativeHealth #ALDH2 #PublicHealth
Unlike alcohol which is metabolized to acetaldehyde within the body, you can also inhale aldehydes. One source of inhaled aldehydes is e-cigarettes and tobacco cigarettes. #aldehydes #ALDH2 #ecigarettes
This #TopicalReview by Katia S. G. Andrade et al. examines targeting #ALDH2 to promote skeletal muscle health as a novel strategy against #mitochondrial dysfunction π π
π Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Because not much is known about endometriosis, we tested the hypothesis that reactive aldehydes and reactive aldehyde accumulation underlies the painful condition of endometriosis.
#Pain #Endometriosis #ALDH2
@ericgross.bsky.social
Despite affecting ~176 million women worldwide, endometriosis screening, detection, and treatment has made little progress.
Many available treatments cause unwanted side effects and are at times ineffective.
#Endometriosis #StanfordAnesthesia #ALDH2
@ericgross.bsky.social
1 in 10 women are affected by endometriosis in their life.
This week, weβre talking about Gross lab research endometriosis and endometriosis-associated pain.
#Endometriosis #StanfordAnesthesia #ALDH2
@ericgross.bsky.social
Commentary by @mendelrandom.bsky.social and me on paper suggesting highly prevalent East Asian #ALDH2 null variant may magnify adverse effects of maternal alcohol use during pregnancy on child development.
βΆοΈ onlinelibrary.wiley.com/doi/10.1111/...
@uob-ieu.bsky.social @bristoluni.bsky.social
www.popsci.com/science/is-a...
Genetics is important! Carriers of a variant in the alcohol metabolism pathway known as ALDH2*2 causes an accumulation of acetaldehyde which is a known carcinogen. Risk of cancer is higher for carriers of this variant. #dryjanuary #alcohol #Aldh2
As part of #dryjanuary ,
it is important to know that the metabolite of alcohol, acetaldehyde, is a class one carcinogen. If you are alcohol intolerant, you will accumulate acetaldehyde, that over time can cause DNA damage that can lead to cancer. #alcohol #genetics #Aldh2
research article from 2016:
Mitochondrial aldehyde dehydrogenase protects against doxorubicin cardiotoxicity through a transient receptor potential channel vanilloid 1-mediated mechanism
doi.org/10.1016/j.bb...
#ALDH2 #TRPV1 #TRPchannels #mitochondria #ToRead
The Aldehyde Hypothesis | Heran Darwin
youtu.be/zLkq6a_W1nE?...
uploaded today
#ALDH2 #NitricOxide #Immunology #malondialdehyde #methylgyoxal #metabolism #WarburgEffect #Immunometabolism