Even though DMS3 is a #Pseudomonas #phage, Nathan showed that Aqs1 could inhibit the function of other #T4P family ATPases, including #T2SS GspE, PilB from #Stenotrophomonas (twitching) and PilB from #Acinetobacter (DNA uptake). These data point to a new allosteric vulnerability of PilB homologues.