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Citrobacter rodentium-infected mouse colon at 8 days postinfection. Mucosal attachment remains unaffected by Eifel2 phage treatment, as visualized via immunofluorescence staining of C. rodentium (green) counterstained with wheat germ agglutinin (purple) and DAPI (blue).

Citrobacter rodentium-infected mouse colon at 8 days postinfection. Mucosal attachment remains unaffected by Eifel2 phage treatment, as visualized via immunofluorescence staining of C. rodentium (green) counterstained with wheat germ agglutinin (purple) and DAPI (blue).

Check out the mBio cover image (Vol 17, Issue 3 - buff.ly/Pqe1IoA) related to our joint publication with the Dept of Life Sciences at @imperialcollegeldn.bsky.social

📰 buff.ly/bcoN2X8

#phage #microbiome #ucc #phagesky #microsky

@uccmicrobiology.bsky.social @colinhillucc.bsky.social @asm.org

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Bacteriophage-Encoded Small RNAs: Emerging Tools for Phage Therapy and Antibacterial Intervention - Aviezer Silverman, Sahar Melamed, 2026 Bacteriophages (phages) are viruses that specifically infect bacteria and play a central role in shaping microbial communities and bacterial evolution. Beyond t...

🚨Happy to share our new mini-review on phage-encoded small RNAs and their potential for phage therapy and antibacterial strategies, written with Aviezer Silverman!
journals.sagepub.com/doi/10.1177/...
#RNA
#phage
@journals.sagepub.com
@hebrewuniversity.bsky.social
@phagedirectory.bsky.social

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#phage #phagesky

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Even though DMS3 is a #Pseudomonas #phage, Nathan showed that Aqs1 could inhibit the function of other #T4P family ATPases, including #T2SS GspE, PilB from #Stenotrophomonas (twitching) and PilB from #Acinetobacter (DNA uptake). These data point to a new allosteric vulnerability of PilB homologues.

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New paper alert! Outstanding work by PhD candidate Nathan Roberge, great collab with the Ellison and Maxwell labs. #Pseudomonas #phage DMS3 encodes Aqs1, an inhibitor of #T4P assembly ATPase PilB, but how it binds and leads to loss of function was unknown. @mcmasteriidr.bsky.social

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Phage The Untouchable: La Comandante “Imposible” Que Convierte Cualquier Error En Derrota Instantánea. Phage the Untouchable es una comandante extrema: si no la “desbloqueas” puedes perder al castearla, pero bien construida encadena derrotas instantáneas y sigue siendo una carta cara y única.

¡🦠💀 Phage the Untouchable: la comandante "imposible" que convierte errores en derrotas instantáneas en Commander! Desbloquéala con Command Beacon o Torpor Orb, protégela con Greaves y elimina rivales. ¡All-in mono-negro letal!

#AncestralGames #Phage #MTGÑ

ancestral.games/articulos/ph...

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A virus hiding inside bacteria may help explain colorectal cancer The gut bacterium Bacteroides fragilis has long presented researchers with a paradox. It has been associated with colorectal cancer, yet it also lives quite happily in most healthy people. A study by…

#Virus hiding inside #bacteria may help explain #colorectal #cancer ...

| #Bacteroides | #microbiome | #bacteriophages | #phage | Via @sciencex.bsky.social

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Conditional activation of Cas13 enforces lysogeny in a native type VI-A CRISPR host - Nature Microbiology RNA-targeting CRISPR in Listeria seeligeri restricts the lytic cycle of temperate phages but tolerates prophage acquisition while also preventing induction—a system that enables acquisition of benefic...

www.nature.com/articles/s41...

#phage #phagesky

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Bacterial Schlafen proteins mediate phage defence - Nature Microbiology This study highlights that Schlafens are ancient, mechanistically conserved immune effectors that mediate antiviral immunity in organisms ranging from humans to bacteria.

#microsky #phagesky #phage defence

www.nature.com/articles/s41...

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Stunning High-Resolution Virus Blueprint Offers New Hope Against Antibiotic Resistance A detailed 3D map of a bacteria-hunting virus reveals ancient origins and new promise against superbugs.

High-Resolution #virus blueprint offers new hope against #antibiotic resistance ...

| #antibioticresistance | #bacteria | #bacteriophages | #phage | By @universityofotago.bsky.social via scitechdaily .com

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Our work on bacterial Schlafens in phage defense is out today @natmicrobiol.nature.com!

Check out the final version here:
rdcu.be/e7Bmz

We are looking for postdocs and students to expand our team! Official postings are coming soon.

Please reach out if you're interested!
#phage #phagesky #microsky

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Prokaryotic defense systems: Diversity and evolutionary adaptation
#microbiology #virology #prokaryotes #archaea #bacteria #virus #phage
@mlifejournal.bsky.social
doi.org/10.1002/mlf2...

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In Our Time - Bacteriophages - BBC Sounds Melvyn Bragg and guests discuss how viruses can help us track and cure bacterial illnesses

🦠 “𝗧𝗵𝗲 𝘃𝗶𝗿𝘂𝘀𝗲𝘀 𝘁𝗵𝗮𝘁 𝗲𝗮𝘁 𝗯𝗮𝗰𝘁𝗲𝗿𝗶𝗮 𝗰𝗼𝘂𝗹𝗱 𝘀𝗮𝘃𝗲 𝘂𝘀 — 𝗯𝘂𝘁 𝗵𝗼𝘄?”

Historian @kirchhelle.bsky.social chats with 𝗠𝗮𝗿𝘁𝗵𝗮 𝗖𝗹𝗼𝗸𝗶𝗲 & 𝗝𝗮𝗺𝗲𝘀 𝗘𝗯𝗱𝗲𝗻 about revival of phage biology & phage therapy as antibiotics fail.

🎧 2024 BBC Radio 4 — listen worldwide:

www.bbc.co.uk/sounds/play/...

#phage #phagesky #microsky

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Safety, recovery, and pharmacodynamics of CRISPR–Cas therapeutic SNIPR001: a phase 1, randomised, double-blind, first-in-human, dose-escalation study This first-in-human study of SNIPR001 supported its safety, tolerability, and restriction to the gastrointestinal tract, while not systemically disrupting the gut microbiome. These results justify fur...

#phage #phagesky

Safety, recovery, and pharmacodynamics of CRISPR–Cas therapeutic SNIPR001: a phase 1, randomised, double-blind, first-in-human, dose-escalation study - The Lancet Microbe www.thelancet.com/journals/lan...

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#microsky #phagesky

On #phage T4:

www.biorxiv.org/content/10.6...

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Prokaryotes face constant viral attacks. A new #mLife review maps the diversity of prokaryotic defense systems and explains how evolutionary arms races with phages drive innovation in microbial immunity. #CRISPR #Phage #Immunity #Evolution
🔗 doi.org/10.1002/mlf2... @wileylifesci.bsky.social

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#microsky #phage #phagesky

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A virus hiding inside bacteria may help explain colorectal cancer Scientists found an unexpected viral hitchhiker lurking inside a common gut bacterium – and it was twice as prevalent in people with colorectal cancer.

#Virus inside #bacteria may help explain #colorectal #cancer ...

| #Bacteroides | #microbiome | #MicroSky | #infections | #phage | Via @theconversation.com

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#microsky #phagesky #phage defence

www.biorxiv.org/content/10.6...

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Convergent MurJ flippase inhibition by phage lysis proteins - Nature A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial devel...

#phagesky #microsky

RNA #phage s synthesise inhibitors of the membrane protein MurJ.

(I might be late to the party, but wanted to post it anyway)

www.nature.com/articles/s41...

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The Star Trek Voyager episode "Lifesigns" aired February 26, 1996.

Full Post
www.facebook.com/photo/?fbid=...

. #TodayInNerdHistory #February26 #StarTrek #StarTrekVoyager #Episode #Lifesigns #Phage #TheDoctor #Viidian #History #Aired #AirDate #News #OTD #FYP #Nerd .

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Ad for Postdoctoral Scientist Position in Burmeister Lab on Bacteria-Phage Coevolution. Full document available here: https://arburmeister.weebly.com/uploads/1/9/9/9/19990727/burmeister_lab_postdoc_position_2026.pdf

Ad for Postdoctoral Scientist Position in Burmeister Lab on Bacteria-Phage Coevolution. Full document available here: https://arburmeister.weebly.com/uploads/1/9/9/9/19990727/burmeister_lab_postdoc_position_2026.pdf

Postdoc position on phage-bacteria coevolution available in the @aburmeister.bsky.social lab at University of Wisconsin - Milwaukee #phage #evosky #MicroSky #VirEvol 🦠 🔬 #microbiology

arburmeister.weebly.com/join-the-lab...

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And The Microbes

OH MY GOSH I JUST FOUND THIS 😃

www.andthemicrobes.org

#comic #bacteria #phage #plasmids 🦠

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#microsky #phagesky #phage #MGE

Prophages found in conjugative megaplasmids from gut Bacillota

www.biorxiv.org/content/10.6...

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Meet Vinay Garg, a junior biochem major and researcher in Prof. Freeman’s lab 🧪 His favorite phage so far is the mycobacterial phage Brilliant. From Columbus, OH, Vinay enjoys time with his puppy, Cali 🐶

Check out a picture of the lab before things get set up!

#CWRU #phage

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#phage #phagesky

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Window art depicting a happy meal box as if it were a rocket (but also looking like a phage)

Window art depicting a happy meal box as if it were a rocket (but also looking like a phage)

Would you look at that? Even fast food chains pay homage to #phage 😝🚀🧪

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Structure and mechanism of antiphage retron Eco2 Nature Structural & Molecular Biology - This study shows how the bacterial retron Eco2 defends against viruses. Phage nucleases trigger activation of Eco2, which cuts RNAs, shuts down protein...

1/6) Hot off the press @natsmb.nature.com 🔥! Jasnauskaite et al. reveal how the minimal bacterial retron Eco2 defends against #phage 🛡️. Phage nucleases trigger Eco2, which cuts RNA, shuts down protein production and stops phage replication 🦠🚫. #phagesky #immunity #microbiology #cryo-em rdcu.be/e4AyH

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Structure and mechanism of antiphage retron Eco2 - Nature Structural & Molecular Biology This study shows how the bacterial retron Eco2 defends against viruses. Phage nucleases trigger activation of Eco2, which cuts RNAs, shuts down protein production and stops phage replication.

#microsky #phagesky #phage defence

www.nature.com/articles/s41...

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Back to Madagascar 🇲🇬 for our 2nd phage field season: exploring eco-evolutionary dynamics in rice fields. Aiming to limit sampling to just 1 year of lab + bioinformatics 😅! Great teamwork between Xplain (@phimresearch.bsky.social) and FOFIFA @mariandm.bsky.social #microsky #phagesky #phage #inrae

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