Latest posts tagged with #Affinitymaturation on Bluesky
#Medsky🧪#IDsky #immunosky #publichealth #Affinitymaturation in germinal centres (GCs) diversifies the #Bcell response & results in antibodies with improved antigen binding. However, antibodies generated early in a response can reshape ongoing GC selection,
IPI teamed up with @deboramarks.bsky.social & Andrew Kruse @harvardmed.bsky.social to design optimized #nanobody binders using #ML on single-sort sequencing data. The approach could speed discovery by reducing the need for multi-sort #affinitymaturation.
Read more:
How the immune system self-instructs to produce #antibodies with increasing affinity to antigens. #affinitymaturation #Bcells www.science.org/doi/abs/10.1126/science....
