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CDK 2.12 Version 2.12 of the Chemistry Development Kit has been released. It is the last release with contributions by our NWO Open Science grant. This release adds some nice new APIs: * harmonize hydrogens to various states: depiction, stereo, minimal, and unsafe (useful for depictions) * generate wedge bonds based on coordinates and stereochemistry * more Markush / RGroup support * atropisomers via CXSMILES * sugar extraction I also update the following libraries/tools to use CDK 2.12: * NanoJava 2.16 * Bacting 1.0.10 (and the Python pyBacting will follow asap)

CDK 2.12 blogpost chem-bla-ics.linkedchemistry.info/2026/03/08/cdk-2.12.html https://doi.org/10.59350/gw9at-srp84

Replies will show up in the blog

#cdk #java #cheminformatics #openscience

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airhacks.fm podcast podcast with adam bien

🎙️☕️"From Gorillas to AWS CDK"--an airhacks.fm podcast conversation with Thorsten Hoeger is ready to listen:
👉 adambien.blog/roller/from_... #java #podcat #CDK

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I Rewrote My Step Function as a Durable Function Ever since AWS announced Lambda Durable Functions at re:Invent 2025, I've been wanting to try them on...

✍️ New blog post by Danielle Heberling

I Rewrote My Step Function as a Durable Function

#aws #function #lambda #cdk

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Why is cdk.out (Cloud Assembly) Necessary in AWS CDK? What is cdk.out cdk.out is a directory that stores a collection of files called the cloud...

✍️ New blog post by Kenta Goto

Why is cdk.out (Cloud Assembly) Necessary in AWS CDK?

#aws #cdk #awscdk

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Building Scalable Web Application on AWS with CDK in TypeScript Introduction Infrastructure as Code (IaC) has revolutionized how we provision and manage...

✍️ New blog post by Chinmay Tonape

Building Scalable Web Application on AWS with CDK in TypeScript

#aws #cdk #typescript #cloudformation

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Building a Highly Available Web Application on AWS with CDK and Python Introduction Infrastructure as Code (IaC) has revolutionized how we provision and manage...

✍️ New blog post by Chinmay Tonape

Building a Highly Available Web Application on AWS with CDK and Python

#aws #cdk #python #cloudformation

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📝 Online now - the Review "Diversity in CDK structural mechanisms of regulation and drug discovery opportunities" from Rhianna Rowland, Martin Noble, and Jane Endicott.

#CDK #Cyclins #ShortLinearMotif #StructureBasedDrugDesign

Read it here: authors.elsevier.com/sd/article/S...

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AWS CDK Community Update: Jan/Feb 2026! What's New Hello! So excited to get the regular blogpost updates on AWS CDK going for...

AWS CDK Community Update: Jan/Feb 2026! What's New Hello! So excited to get the regular blogpost updates on AWS CDK going for 2026! This update covers CDK updates from December 2025 through Feb...

#aws #cdk #opensource #devops

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CDK Quarterly Community Meeting (Session 2) · Zoom · Luma For the AWS CDK open-source community to meetup virtually and discuss: Recent launches Community-built open-source projects Join the discussion here -…

We had a really fun session on CDK Community Meeting! If you missed it, there is another one in 3 hours from now for our EU and APJ friends-

Session 2 - luma.com/5ar52zni / 3AM EST on 12th February (Thursday)

Join us to see some cool new things we are building on CDK.

#aws #cdk @cdk.dev

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Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ... PURPOSEIn both the early and advanced settings, cyclin-dependent kinase 4/6 (CDK4/6) inhibitors are approved for use in hormone receptor–positive/human epidermal growth factor receptor 2–negative (HER...

Niveles circulantes de la actividad de timidina quinasa en plasma son un buen biomarcador pronóstico y predictivo continuo de respuesta a la terapia con CDK4/6 en pacientes con cáncer de mama positivo para el receptor hormonal y HER2 #TKa #CDK #breastcancer ascopubs.org/doi/abs/10.1...

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