Latest posts tagged with #StructureBasedDrugDesign on Bluesky
📝 Online now - the Review "Diversity in CDK structural mechanisms of regulation and drug discovery opportunities" from Rhianna Rowland, Martin Noble, and Jane Endicott.
#CDK #Cyclins #ShortLinearMotif #StructureBasedDrugDesign
Read it here: authors.elsevier.com/sd/article/S...
📝 Online now - the Review "Structural transport and inhibition mechanism of the mitochondrial pyruvate carrier" from Edmund Kunji (@mrc-mbu.bsky.social) and co.
#SLC54 #MPC #EnergyMetabolism #MembraneProteinStructure #StructureBasedDrugDesign
Read it here 👉 authors.elsevier.com/sd/article/S...
In 216 ligand-bound structures of human FABP isoforms, many at better than 1.2 Å resolution, an estimated 15% of the ligands had a different chemical composition to that expected #StructureBasedDrugDesign #FattyAcidBindingProteins #LigandBinding doi.org/10.1107/S205...
Andreas Ehler et al.: A high-resolution data set of fatty acid-binding protein structures. III. Unexpectedly high occurrence of wrong ligands #StructureBasedDrugDesign #FattyAcidBindingProteins #LigandBinding doi.org/10.1107/S205... #IUCr
