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Clinical and Genetic Insights Into Isolated #Proteinuria With #CUBN Variants

#VisualAbstract by @Cteodosiu

www.kireports.org/article/S2468-0249(25)00...

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Figure 2. (A) Schematic representation of CUBN protein structure and binding regions, along with location of this patient’s variants. (B) Summary of patient genetic variants. (*) indicates nonsense mutation.

Figure 2. (A) Schematic representation of CUBN protein structure and binding regions, along with location of this patient’s variants. (B) Summary of patient genetic variants. (*) indicates nonsense mutation.

In this case report, the authors demonstrate mutations in #CUBN lead to stable #albuminuria without affecting the #eGFR. Chronic benign tubular albuminuria does not require intervention!
#kidneywk @ubcmedicine.bsky.social @cjkhd.bsky.social @csnscn.bsky.social

doi.org/10.1177/2054...

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The opposite of #BUCN is #CUBN.

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