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Posts tagged #Proteinuria

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Clinical and Genetic Insights Into Isolated #Proteinuria With #CUBN Variants

#VisualAbstract by @Cteodosiu

www.kireports.org/article/S2468-0249(25)00...

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Nonprogressive #Nephrotic Range #Proteinuria Because of Indirect #Cubilin Dysfunction

https://doi.org/10.1016/j.ekir.2025.09.046

#KIRNephrologyRounds

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Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nep

Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nep

#Safranal protects against membranous #glomerulonephritis in rats by reducing #proteinuria, #inflammation, and #podocyte injury; restoring #nephrin/podocin levels; and suppressing NF-κB-driven renal inflammation via Sirt1 pathway activation.

#OpenAccess: doi.org/10.1007/s115...

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💊FDA Approval Update | #FDA approved #Voyxact (#sibeprenlimab-szsi) for #IgAN to reduce #proteinuria
🌟#VISIONARY (a Phase III trial): achieved 50% reduction in proteinuria at 9 months
🔸MedChemExpress provides sibeprenlima for research use only

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A graphic illustrating diagnostic approaches for different types of podocytopathy.

A graphic illustrating diagnostic approaches for different types of podocytopathy.

Asymptomatic #proteinuria is commonly detected incidentally and identifying the aetiology of an underlying #podocytopathy requires distinct diagnostic approaches.
https://www.nature.c

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🌱 Esperanza para pacientes con nefropatía por IgA
💊 Atrasentán clorhidrato, desarrollado por Novartis
💊 Dirigido a reducir la proteinuria
📧 info@dengyuemed.com

#AtrasentánClorhidrato #AtrasentánTabletas #IgAN #Glomerulonefritis #SaludRenal #Proteinuria #DengYueMedicinasEnHongKong

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129S2/SvPas mice are susceptible to #hypertension from dietary #electrolyte manipulation. In a #doxorubicin-induced #proteinuria model, 129S2/SvPas mice proved resistant to proteinuria compared to 129S1/SvImJ mice, and proteolytic processing of #renal #ENaC was not increased
doi.org/10.14814/phy...

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Zigakibart Demonstrates Safety and Efficacy in Phase 1/2 Trial | Docwire News Zigakibart showed good tolerability, reduced proteinuria by 60%, and stabilized kidney function in patients with IgA nephropathy (IgAN) over 100 weeks of treatment.

Zigakibart was well tolerated and cut #proteinuria by 60% while stabilizing #kidney function in #IgAN patients over 100 weeks. #nephrology #nephsky #iganephropathy docwirenews.com/post/zigakib...

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Felzartamab Reduces Proteinuria in Patients with IgA Nephropathy | Docwire News A study showed that felzartamab produces a sustained reduction in proteinuria for patients with IgA nephropathy (IgAN).

Felzartamab produces a sustained reduction in #proteinuria for patients with #IgAN, a study shows. #nephsky #nephrology #iganephropathy docwirenews.com/post/felzart...

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Proteinuria Treatment Market Size, Trends, Growth, Report 2034 Proteinuria Treatment Market is projected to register a CAGR of 7.17% to reach USD 4.39 billion by the end of 2032, Global Proteinuria Treatment Industry analysis by Disease Type, Drug Class, Route of...

🧬 Kidney health matters! 👩‍⚕️ Proteinuria treatment market is expanding with advanced therapies.

#KidneyHealth #Proteinuria #MedicalResearch #Healthcare

www.marketresearchfuture.com/reports/prot...

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as defined by #proteinuria. By contrast, vaccination against COVID was not associated with change in disease activity or kidney function decline. These results support COVID vaccination for patients with GN.
www.sciencedirect.com/science/arti...

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IgA Nephropathy: What Is New in Treatment Options?
#OpenAccess
Full text 👉 buff.ly/1ywFl0z

#IgAN
#Nephrology
#BergerDisease
#Glomerulonephritis
#Proteinuria
#KidneyHealth
#CKD
#Nephrology
#nephsky
#medsky
#RenalPath

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Fuzzy (foamy) urine — what your body might be trying to tell you 🧬💧

Subscribe to read more on www.pouringpotions.com

#FoamyUrine #Proteinuria #KidneyHealth #UrineAwareness #KidneyDisease #MedicalInfo #HealthEducation #EarlyDetection #StayHydrated #ChronicDisease

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Do you treat #IgAN?

Check out this free KDIGO-@medliveofficial.bsky.social-NORD #CME credited webinar about why #proteinuria reduction matters, how #KDIGO guidelines shape care, and what new therapies targeting endothelin-1 and angiotensin-2 mean for your patients: bit.ly/4eIKu6N

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Non-hepatic #PCSK9

PCSK9 targets LRP2/Megalin to lysosomal degradation in renal proximal tubule cells

Megalin mediates PCSK9 uptake in renal epithelium

PCSK9 KO🐭 or Alirocumab in WT or nephrotic Nphs2-/-🐭
⏫renal Megalin & LDLR
#Proteinuria

#KidneyInt 2023
www.sciencedirect.com/science/arti...

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Pegcetacoplan Benefits Patients With C3G/IC-MPGN and Nephrotic Proteinuria | Docwire News An analysis confirmed the efficacy and safety of pegcetacoplan for patients with C3 glomerulopathy and primary immune complex membranoproliferative and nephrotic range proteinuria.

An analysis confirmed the efficacy and safety of #pegcetacoplan for patients with C3G/IC-MPGN and nephrotic range #proteinuria. #C3G #ICMPGN #kidneydisease #nephrology #nephsky www.docwirenews.com/post/pegceta...

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Proteinuria Trajectory Predicts Progression of IgA Nephropathy | Docwire News Proteinuria trajectory is a major predictor of disease progression in children and adults with IgA nephropathy (IgAN), a study found.

Identifying patients with #IgAN who are at risk for disease progression is critical—and #proteinuria trajectory is a major predictor. #nephrology #iganephropathy #nephsky www.docwirenews.com/post/protein...

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Phase 3 Data Show Sibeprenlimab Reduces Proteinuria in IgAN | Docwire News Phase 3 VISIONARY trial data presented at the ERA Congress 2025 showed sibeprenlimab helps achieve significant proteinuria reduction in patients with IgA nephropathy (IgAN).

Interim results of VISIONARY presented in a late-breaking abstract at #ERA25 showed that #sibeprenlimab helps achieve significant #proteinuria reduction in patients with #IgAN. #IgAnephropathy #nephrology #nephsky www.docwirenews.com/post/phase-3...

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Monoclonal Gammopathy of Renal Significance (MGRS): Overview, Diagnosis, and Management
#DVP183
#MGRS #KidneyDisease #Nephrology #Amyloidosis #VikaasLLC #LCDD #KidneyBiopsy #Bortezomib #Rituximab #Daratumumab #MGUS #Myeloma #Proteinuria #ESKD

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Massive reduction in #proteinuria without increase in side effects.

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Early #proteinuria (protein in urine) is often a first sign of kidney involvement in cystinosis. (Orphanet Journal of Rare Diseases, 🔗 in bio0

We had to put a urine sample collection bag on Oliver at 12mo old to test what was going on, anyone else had to do that with a little one? #ShareYourRare

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NICE recommends sparsentan for IgA nephropathy - PharmaTimes First non-immunosuppressive dual-action therapy approved for eligible patients

#renalmedicine #CSLVifor #nephrology #sparsentan #FILSPARI #IgAnephropathy #nonimmunosuppressivedualactiontherapy #NICE #NHS #primaryIgAnephropathy #PROTECTcliicaltrial #NICEguidance #IgAnephropathypatients #primaryglomerulardisease #kidneyfailure #Proteinuria
pharmatimes.com/news/nice-re...

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Role of vitamin D in the development and progression of diabetic kidney disease: an overview of meta-analyses - Ashna Chackochan, Muhammed Rashid, Swetha R. Reghunath, Pooja Gopal Poojari, Girish Thun... Background: The effectiveness of vitamin D supplementation in the progression of diabetic kidney disease (DKD) remains controversial. Our review tries to provid...

New evidence links low #vitaminD levels to #diabetickidneydisease -sunlight could be more vital than we thought.☀️
The study suggests that while vitamin D supplements may help reduce #proteinuria, it has no significant impact on other measures of #kidney function. doi.org/10.1177/2042...

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Comparison of Sparsentan and Irbesartan in FSGS | Docwire News A study compared effects of sparsentan vs irbesartan on proteinuria remission in focal segmental glomerulosclerosis (FSGS) and how remission affected progression to kidney failure.

Researchers assessed effects of sparsentan vs irbesartan on #proteinuria remission and how achieving complete or partial remission affected progression to #kidneyfailure. #NKFClinicals #nephrology #nephsky www.docwirenews.com/post/compari...

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Proteinuria Remission With Sparsentan in FSGS | Docwire News Joel Topf spoke with James Tumlin at the National Kidney Foundation Spring Clinical Meetings about a late-breaking abstract on sparsentan in focal segmental glomerulosclerosis.ne

DON'T MISS @kidneyboy.bsky.social in conversation with James Tumlin at #NKFClinicals, discussing the latter's late-breaking abstract on sparsentan and #proteinuria remission in #FSGS. #nephrology #nephsky #kidneydisease www.docwirenews.com/post/protein...

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Expert Review

Urine Protein Tests in Systemic Lupus Erythematosus: What Do They Mean?

📖 doi.org/10.3899/jrhe...
@uoft.bsky.social

#lupusnephritis #proteinuria #lupus

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The Texas State Plan for #CKD #Chronic #Kidney #Disease Treatment, is 🔥 💪
www.hhs.texas.gov/sites/defaul...
Key points:
1) Expands early screening
2) Acknowledges socioeconomic factors in CKD
3) Integrates #proteinuria #EGFR & #genetics
4) School screening for proteinuria & #hypertension

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Original post on mastodon.social

The Texas State Plan for #CKD #Chronic #Kidney #Disease Treatment, is 🔥 💪
www.hhs.texas.gov/sites/default/files/docu...
Key points:
1) Expands early screening
2) Acknowledges socioeconomic factors in CKD
3) Integrates #proteinuria #EGFR & […]

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BioCity’s SC0062 Met End Point for DKD in Phase 2 Trial | Docwire News SC0062, a selective endothelin receptor type A antagonist, met the 12-week primary end point of a reduction in proteinuria in a study cohort with diabetic kidney disease (DKD).

SC0062 reduced #proteinuria in #DKD at 12 weeks. #diabetickidneydisease #nephrology #nephsky

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