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Five projects share £100m UK-US Cancer Grand Challenges fund Five scientific teams will receive up to £20m each in a new round of funding under the UK and US Cancer Grand Challenges initiative.

#CancerGrandChallenges #CRUK #NCI #UK #USA #oncology #cancer #ATLAS #INSERM #autoantibodies #tumours #REWIRECAN #UCLCancerInstitute #ILLUMINE #NetherlandsCancerInstitute #darkproteome #proteins #immunotherapies #antigenicmarkers #CAUSE #InteroCANCEption #FrancisCrickInstitute
zurl.co/P9eTF

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🚀 Encuentro de Cancer Grand Challenges

Participamos en Londres en el encuentro de Cancer Grand Challenges, una iniciativa internacional impulsada por Cancer Research UK que promueve proyectos colaborativos para abordar algunos de los retos en cáncer.
#CancerGrandChallenges #ContraelCancer #Research

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Team Led by UC San Diego Researchers Selected for Prestigious Global Cancer Prize With up to $25 million from Cancer Grand Challenges, an international team led by UC San Diego professor Ludmil Alexandrov, will unlock the secrets of DNA's

UC San Diego Team CAUSE, led by Dr. Ludmil Alexandrov, @UCSDMedSchool.bsky.social, @jacobsschool.bsky.social, @UCSDCancer has won up to $25M from #CancerGrandChallenges to unravel the mysteries of mutational signatures in #cancer & develop new prevention & treatment strategies

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CGC Discover 25/26

We are excited to launch Discover, our annual progress magazine showcasing a year of extraordinary scientific breakthroughs and the latest #CancerGrandChallenges announcements.

🔗 Read the newest edition here:
features.cancergrandchallenges.org

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Five #scientificteams from around the world will receive up to £20 million each in a new round of #funding under the UK and US #CancerGrandChallenges initiative.

buff.ly/8wVGLmt

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Team ILLUMINE of the Cancer Grand Challenges in New York City in December 2025

Team ILLUMINE of the Cancer Grand Challenges in New York City in December 2025

So honored to be a part of team ILLUMINE for the new #CancerGrandChallenges for the #DarkProteome.

Excited to crack open this new field in cancer biology!

Full announcement: www.cancergrandchallenges.org/new-teams-an...

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We're so proud of our faculty members who have won #CancerGrandChallenges funding - Leanne Li will lead team InteroCANCEption, investigating how the brain and nervous system sense and respond to changes in the body. They will explore how the brain might detect tumours and influence how they grow.

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Congratulations to our faculty members who have received #CancerGrandChallenges funding! Bart Vanhaesebroeck will lead REWIRE CAN with @christophertape.bsky.social and @vivianlilab.bsky.social, unpicking the way cancer develops by using optimal oncogenic signalling to cause permanent cell division.

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UCL-led international research team wins $25m Cancer Grand Challenges funding Team REWIRE-CAN, led by Professor Bart Vanhaesebroeck of the UCL Cancer Institute, will receive up to $25m over approximately five years to take on the rewiring cancer cells challenge.

Congratulations to Prof Bart Vanhaesebroeck, Prof @christophertape.bsky.social & Team REWIRE-CAN on securing $25m in @cancergrand.bsky.social funding to take on the challenge of rewiring cancer cells.

#CancerGrandChallenges @uclmedsci.bsky.social

www.ucl.ac.uk/news/2026/ma...

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The project, InteroCANCEption, lead by @crick.ac.uk, will investigate whether neural circuits can shape cancer progression, and could open the door to entirely new therapeutic strategies 💡.
Funded by Cancer Research UK and the National Cancer Institute in the US through #CancerGrandChallenges.

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The project, InteroCANCEption, lead by @crick.ac.uk, will investigate whether neural circuits can shape cancer progression, and could open the door to entirely new therapeutic strategies 💡.
Funded by Cancer Research UK and the National Cancer Institute in the US through #CancerGrandChallenges.

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O projeto, InteroCANCEption, liderado @crick.ac.uk, irá investigar se os circuitos neurais influenciam a progressão do cancro, abrindo caminho a novas estratégias terapêuticas💡.
Financiado pela Cancer Research UK e pelo National Cancer Institute dos EUA, através da iniciativa #CancerGrandChallenges.

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Team CAUSE with Juan Garaycoechea and @puckknipscheer.bsky.social has been selected to receive a @cancergrand.bsky.social award to tackle the mechanisms driving mutational signatures challenge. Congratulations! https://www.hubrecht.eu/cgc-team-cause/ #CancerGrandChallenges

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Man and woman smile at the camera

Man and woman smile at the camera

Two of our researchers will help tackle one of cancer’s toughest challenges.

They are part of team ATLAS, who have been selected to receive a @cancergrand.bsky.social @cancerresearchuk.org award of $25m ➡️ buff.ly/dcJb8Kb

#CancerGrandChallenges

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We’re excited to reveal that team ILLUMINE led by Reuven Agami has been selected by Cancer Grand Challenges to to take on one of cancer’s toughest challenges. Congratulations to Reuven and all the #CancerGrandChallenges teams! ➡️nki.nl/news-events/news/illuminating-cancer-s-hidden-layer/

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🎧 New podcast feature

Prof. Kimmie Ng, from the Cancer Grand Challenges team OPTIMISTICC, was recently interviewed on Podnosis, the Fierce Healthcare podcast exploring the biggest trends and challenges shaping healthcare today.

In the episode, Prof. Ng discusses why colorectal cancer rates are rising in younger people — including the role of diet, lifestyle, environmental exposures, obesity, and the microbiome. As part of OPTIMISTICC, her team is leading an international cohort study to better understand the mechanisms driving young-onset colorectal cancer.

▶️ Listen to the full podcast:
https://www.fiercehealthcare.com/providers/how-doctors-are-rethinking-care-colorectal-cancer-shifts-younger

#CancerGrandChallenges #CancerResearch #ColorectalCancer #GlobalHealth #HealthInnovation

🎧 New podcast feature Prof. Kimmie Ng, from the Cancer Grand Challenges team OPTIMISTICC, was recently interviewed on Podnosis, the Fierce Healthcare podcast exploring the biggest trends and challenges shaping healthcare today. In the episode, Prof. Ng discusses why colorectal cancer rates are rising in younger people — including the role of diet, lifestyle, environmental exposures, obesity, and the microbiome. As part of OPTIMISTICC, her team is leading an international cohort study to better understand the mechanisms driving young-onset colorectal cancer. ▶️ Listen to the full podcast: https://www.fiercehealthcare.com/providers/how-doctors-are-rethinking-care-colorectal-cancer-shifts-younger #CancerGrandChallenges #CancerResearch #ColorectalCancer #GlobalHealth #HealthInnovation

🎧 Podcast feature: Prof. Kimmie Ng from #CancerGrandChallenges team #OPTIMISTICC on #Podnosis with @gliadkovskaya.bsky.social.

She explores the challenges of colorectal cancer rise in younger people.

▶️ www.fiercehealthcare.com/providers/ho...

#CancerResearch #ColorectalCancer #CancerInnovation

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https://www.aacr.org/about-the-aacr/newsroom/news-releases/aacr-announces-fellows-of-the-aacr-academy-class-of-2026/

https://www.aacr.org/about-the-aacr/newsroom/news-releases/aacr-announces-fellows-of-the-aacr-academy-class-of-2026/

🎉 Congrats to #CancerGrandChallenges team members elected to the 2026 @theaacr.bsky.social Academy Fellows** 🎉

👏 Kimberly Stegmaier (PROTECT)
👏 Ben Cravatt (eDyNAmiC)
👏 Garry P. Nolan (STORMing)
👏 Anthony G. Letai #NCI

Honouring leaders advancing cancer research.
🔗 www.aacr.org/about-the-aa...

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Scientists may have found key to treating hidden cancer growths Researchers say the findings offer a promising way to improve existing cancer therapies as well as develop new ones

Read about #CancerGrandChallenges Team #KOODAC’s innovative study, featured this week in @the-independent.com 👇
🔗 independent.co.uk/news/health/...

Funded through @cancergrand.bsky.social l by @cancerresearchuk.org , @institut-cancer.bsky.social & #Kika.

#CancerResearch #ImmunoOncology #MYC

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🎟️ Register for the #CancerGrandChallenges conference – Cancer and the host

📝 Register now
📥 Abstract deadline 20 March
🗓️ 17–19 June 2026
📍@The Royal Society, London

🔗 cancergrandchallenges.org/conferences/cancer-and-the-host

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HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors HLA-Shuttle enhances production of HLA class I molecules in neuroblastoma, leading to the discovery of tumor-associated antigens.

Researchers Nikolaos Sgourakis and John Maris from team NexTGen (co-funded by @themarkfdn.bsky.social) created a discovery system to identify new antigens in neuroblastoma.

📖 Read the Science Advances paper: doi.org/10.1126/scia...

#CancerResearch #neuroblastoma #CancerGrandChallenges

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Register now for the #CancerGrandChallenges conference Spatial biology. A gathering of global leaders in research, technology, & clinical care.
📝 Register now
📥 Abstract deadline 15 May
🗓️ 1 - 3 September 2026
📍The Royal Society, London
🔗 cancergrandchallenges.org/conferences/spatial-biology

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The #CancerGrandChallenges impact reports reflect not just research milestones — but the power of global collaboration and visionary thinking to tackle some of cancer’s toughest challenges.

🔗 Explore the full impact reports here: lnkd.in/eGctd2rD

#CancerResearch #TeamScience

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Cross-National Radiomics Validation Using Mammography to Predict Occult Invasion in Ductal Carcinoma in SituRadiology Mammographic radiomic features were able to predict occult invasive disease in core-needle biopsy–proven ductal carcinoma in situ in patients from three countries.

What if we could spot #cancer before it strikes — or while it’s still treatable? A new study published in
@rsnasky.bsky.social is bringing us a step closer to that goal.

🔗 Read more doi.org/10.1148/radi...

Congratulations to Joseph Lo, Shelley Hwang and the #CancerGrandChallenges PRECISION team.

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Read the newly published impact report from the SPECIFICANCER team that reshaped our understanding of tissue specificity.

Thanks to our co-funders, @themarkfdn.bsky.social, for supporting the #CancerGrandChallenges team and global science.

🔗 lnkd.in/eDrQ9guu

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🧬 Sponsor the #CancerGrandChallenges Spatial biology conference and join the community redefining how we see cancer.

Help accelerate the next generation of spatial approaches that could revolutionise cancer diagnosis and treatment.

Find out more: lnkd.in/e-7iZF6d

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Clarivate Highly Cited Researchers 2025 The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...

We’re proud to share that 25 individuals from our international #CancerGrandChallenges community have been named among the @clarivate.com #highlycited2025.

To every awardee across our community congratulations, and thank you for your leadership and impact 👏. Read more ow.ly/y23050XohmV

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Honored to be part of this year’s Future Leaders’ Conference in Milan! Sharing science, hearing new ideas, and meeting inspiring people made it unforgettable. Thank you @cancergrand.bsky.social , #TeamCANCAN and Eileen White lab for this opportunity ✨

#CancerGrandChallenges #WomenInCachexia

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That’s a wrap for Future Leaders' Conference 2025!

This conference wasn’t just about sharing what’s been done—it was about igniting what comes next. The optimism and connections we witnessed will drive real progress in tackling some of the hardest questions in cancer #FLC25 #CancerGrandChallenges

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🔬 New research from #CancerGrandChallenges team PROSPECT explores possible links between diet and risk of bowel polyps in younger women.

🔗 Read more www.cancergrandchallenges.org/news/an-asso...

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“Take the most exciting options, take risks and be bold”

Words from Karen Vousden, Principal Group Leader at @crick.ac.uk and #CancerGrandChallenges Scientific Committee member, at day one of our Future Leaders’ Conference 2025 #FLC25

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