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#CannabinoidReceptor

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Posts tagged #CannabinoidReceptor

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Role of CB2 cannabinoid receptor in the development of food addiction in male mice The endocannabinoid system plays an important role in multiple behavioral responses due to its wide distribution in the central nervous system. The ca…

2️⃣García-Blanco et al., 2023 www.sciencedirect.com/science/arti...
📖 #CB2 #CannabinoidReceptor & the development of food addiction in mice

💡CB2R is a modulatory node in the control of hedonic feeding and vulnerability to #FoodAddiction, making it a potential therapeutic target for eating disorders

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Speaking of #allostery: What happens when you mutate the #CannabinoidReceptor (CB1) in silico with a single-point mutation?

Find out👉: doi.org/10.1021/acso...

Spoiler😉: The F237L mutation mimics #allosteric #ligand effects, globally altering #receptor conformations and hindering activation

#GPCR

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