#Article in #MedComm
Discovery of a Novel Non-Nucleoside Inhibitor of RNA-Dependent RNA Polymerase Against Dengue Virus doi.org/10.1002/mco2...
#AG129mice #DengueVirus #DENV #ICRsuckling #Target #PN_1
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#DENV
Latest posts tagged with #DENV on Bluesky
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Posts tagged #DENV
WOW! Systematic testing of 2 #Wolbachia strains for their ability to block transmission of 60 genetically diverse #DENV isolates in #mosquitoes shows substantial heterogeneity and suggests potential long-term selection risks in Wolbachia-based control interventions.
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🌐 Meet GISDD — an #AI-powered #Bioinformatics platform for fast dengue virus (DENV) genotyping & tracing.
Upload your sequence ➡️ get instant genotype, origin & risk insights.
Supporting global DENV surveillance & collaboration.
#DENV #Genomics #PublicHealth onlinelibrary.wiley.com/doi/10.1002/...
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Using an in vivo CRISPR/Cas9-mediated approach, we provide the first dynamic insight of a Vago-like gene’s function during #flavivirus infection of #Aedes #aegypti 🦠. Our findings suggest that VLG-1 supports #DENV and #ZIKV virus by promoting its dissemination throughout the mosquito’s body. 🤯
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Super psyched to have leading investigator @thehornerlab.bsky.social presenting her team's work THURSDAY 15th May on Zoom.
#flavivirus #virus-host-interactions #innate_immunity #DENV #ZIKV
All are very welcome and please re-post to get the word out. Email organisers for Zoom link. See you there!
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New Vector of the Month: #Aedes #aegypti, the main #mosquito vector of #dengue, #chikungunya, #Zika & #YellowFever viruses, authored by Jacquelyn LaReau & @agloriasoria.bsky.social. #DENV #CHIKV #ZIKV #YFV
authors.elsevier.com/a/1ksqE5Eb1x...
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The burden of viral disease in many African countries is underreported. Here, using the latest #sequencing approaches, this much needed study has identified the viral aetiology in patients with #fever. Numerous (re) emerging #arboviruses of concern found; #CCHFV #YFV #RVFV #DENV
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Happy to share our recent study on the mechanism of a clinical #DENV inhibitor, NITD-688. For someone with a background in biophysics, it's also a learning journey into #virology, #antiviral, and academia/industry collaboration. Thanks Xuping, Pei-Yong and all the collaborators at UTMB/Novartis!
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🚨 New Project Publications! 🚨
Two studies from our #EDCTP -funded #GenPathAfrica consortium used genomic analysis to
🧬 provide the first in-depth analysis of #DENV in Ethiopia
🧫discover #TB in shared water sources in rural South Africa, where TB-spread is high
Read more▶️ tinyurl.com/44hwxuuu
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Check out our latest preprint revealing the unexpected role of a #mosquito cytochrome P450 in #DENV susceptibility! While P450s are typically associated with #insecticide resistance, we show they can also have #antiviral activity. This long-term effort was brilliantly led by @merklinglab.bsky.social
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#MeetTheLab
This week, we are happy to introduce the Zitzmann Lab from @oxfordbiochemistry.bsky.social
The lab focuses on developing antiviral therapies to address #HepatitisB ( #HBV), #HepatitisC ( #HCV), human immunodeficiency virus ( #HIV), #DengueVirus ( #DENV), #Ebola, and #influenza.
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Nice study from @leendelang.bsky.social's lab shows that the pan-serotype #DENV inhibitor JNJ-A07 impedes virus transmission in the #mosquito vector Aedes aegypti | Science Advances www.science.org/doi/10.1126/...
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A very interesting study on how JNJ-A07 can also reduce #DENV transmission by mosquitoes
www.science.org/doi/10.1126/...
cen.acs.org/pharmaceutic...
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Check out our interview with #ASV2024 Global Scholar Cybele Garcia, from the University of Buenos Aires in Argentina, who studies molecular mechanisms of #Juninvirus #DENV #ZIKV to develop new #antiviral #therapeutics. #lovevirology www.podbean.com/ep/pb-7vqec-...
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Check out our interview with #ASV2024 Global Scholar Tatiana Murillo Corrales, from the University of Costa Rica, who will present her work characterizing a #DENV and #ZIKV outbreak in Costa Rica. #lovevirology
www.podbean.com/ew/pb-2x8de-...
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