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DIS3 licenses B cells for plasma cell differentiation in humans - Cellular & Molecular Immunology Cellular & Molecular Immunology - DIS3 licenses B cells for plasma cell differentiation in humans

Look at DIS! #DIS3 #RNAExosome #PlasmaCells

www.nature.com/articles/s41...

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Cellular imbalance of specific RNA binding proteins associates with harmful R-loops Author summary R-loops are three-stranded structures formed by a DNA-RNA hybrid and the displaced ssDNA. The accumulation of R-loops damages the genome, highlighting the need for their tight regulatio...

#Dis3 #Rloop #RBP #RNAExosome #RNA

journals.plos.org/plosgenetics...

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Cool 😎

#DIS3 #Exosome #Independent
#circRNA #RNADegradation
#RNA #RNAsky

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Nice keynote by Ling-Ling Chen: #DIS3 and #circRNA #Degradation
#RNA25

www.cell.com/molecular-ce...

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Degradation of circular RNA by the ribonuclease DIS3 Features of circular RNAs (circRNAs) produced by back-splicing of eukaryotic exon(s) make them resistant to degradation by linear RNA decay machinerie…

DIS is interesting!
#circRNA #Degradation #DIS3 #Ribonuclease #RNAExosome

www.sciencedirect.com/science/arti...

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