Latest posts tagged with #GIsky on Bluesky
Short review of post op ileus (POI), acute colon pseudo-obstruction(ACPO)
🤔POI: review MEDS; labs; ambulation
🤔Enteral feeding of benefit (POI)
🤔? SC methylnaltrexone for ACPO
🤔? prucalopride for POI & ACPO
🤔? value of chewing gum to prevent POI
🤔Does coffee prevent POI?
#Medsky #IMsky #GISky
In a large real-world study, more than 60% of patients with #CrohnsDisease treated with #risankizumab achieved steroid-free clinical remission by week 12, and through 1 year of treatment.
#Gastroenterology #GISky #inflammatoryBowelDisease #IBDSky
cALD in US: Common; 85% of pts unaware they have it
🤔Compensated ALD in asymptomatic pts.
🤔Weighted preval of cALD in us 2.4%; possible cALD 3.46%
🤔85% unaware (This surprised me)
Another reminder to screen with FIB-4 and/or Elastography
#IMSky #GISky #Medsky
Colonic delivery of #FecalMicrobiotaTransplantation was a more effective route than nasogastric administration for patients with #UlcerativeColitis.
#Gastroenterology #InflammatoryBowelDisease #IBDSky #GISky #FMT
Add Statins to our Water? Statins associated with lower risk of HCC and Hepatic decompensation in cirrhosis
🤔Umbrella review ( EASL) 168 studies, 10 mil pts
🤔Reduced risk of HCC (HR 0.53)and decompensation
(HR 0.54)
Continue statins in these patients
Food for thought?
#IMsky #GIsky #Medsky
Heading to DDW? 🧠 Save the date! 📆 Come connect at the #pedsgastropsych meet up! Check out the image for details — we’re gathering Sunday, May 3rd from 11am–Noon central. Join us for community, collaboration, and a chance to meet colleagues across GI psych! #DDW2026 #GISKY #PGSIG #Div54 #pedsGI
Coffee Barrett's and Gerd
🤔Review/meta-analysis
🤔Coffee associated with marginal 🔼 Gerd, but not Barrett's. "routine avoidance/reduction of coffee intake ...needs further evaluation"
👍Perhaps restrict in pts who identify it as a trigger, or improve with cessation. Not routinely
#medsky #GIsky
Taryn Lores, PhD, of the Icahn School of Medicine at Mount Sinai, discusses integrating #BehavioralIntervention therapy into treatment for patients with #CrohnsDisease.
#IBDSky #GISky
#GLP1 receptor agonists may be a safe and beneficial option for managing #obesity and metabolic comorbidities for adults with #InflammatoryBowelDisease.
#GISky #IBDSky
AI-driven increases in nonadvanced adenoma detection during #Colonoscopy may meaningfully increase surveillance burden with unclear long-term benefit.
#GISky #ColorectalCancer #ArtificialIntelligence
Real-world data presented at #CCCongress26 suggest IV and SC #vedolizumab have similar overall safety and efficacy in IBD, but IV use was linked to higher hospitalization and steroid use (#UlcerativeColitis) and higher shock rates (#CrohnsDisease). #IBDSky #GISky
Phase 1b data suggest early efficacy signals for APL-1401, a first-in-class DBH inhibitor, in moderate-to-severe #UlcerativeColitis. Results presented at the #CCCongress26 support further dose evaluation. #GISky #IBDSky
Let's hear it for short sleeves
🤔Long Sleeves cultured. 280 samples. 81% bacterial growth, 20.7% with potential pathogens. Fleece most likely to be contaminated.
No evidence of spread.
Even so lets hear it for "bare below the elbows."
#IMsky #Medsky #GIsky
Early CATHARSIS trial data presented at #CCCongress26 suggest combining biologics with structured #BrainGut behavioral therapy may improve well-being in moderate-severe #CrohnsDisease. High feasibility, satisfaction, and retention reported. #IBDSky #GISky
Will PPI's ever be vindicated?
🤔Duru in BMJ - No association between PPI and Gastric
Adenocarcinoma.
🤔Ed (see below): Recognizing the conflicting and uncertain evidence base on PPI ...harms, suggest concern about adverse effects alone...not a reason to avoid prescribing.
#IMsky #GIsky #Medsky
Phase 1 data presented at #CCCongress26 highlight ATH-063, a first-in-class oral G9a inhibitor. In healthy volunteers, it showed favorable PK, no safety signals, and strong FoxP3+ Treg activation—supporting further study in biologics-resistant IBD.
#IBDSky #GISky
Real-world data presented at #CCCongress26 suggest #GLP1 RAs may benefit #CrohnsDisease patients with overweight/obesity. #GLP1RA use was linked to lower steroid dependence, fewer hospitalizations, and improved durability of advanced IBD therapy. #IBDSky #GISky
Real-world data presented at #CCCongress26 suggest GLP-1 receptor agonists may improve #InflammatoryBowelDisease outcomes. In IBD, #GLP1 RA use was linked to lower steroid use, hospitalizations, surgery, and mortality, supporting further study. #GISky #IBDSky
Alfapump....? Interesting idea for refractory ascites
🤔Pumps ascitic fluid into badder
🤔Role unclear; ? if not candidates for Liver Txp, or TIPS
?Preferable to repeated large vol taps
Interesting article reviewing selection of pts and how it is placed.
#IMsky #GIsky #Medsky
A new season of Digestibles is coming! In partnership with Olympus, ASGE offers FREE, bite-sized GI learning with 5-minute case-based questions and real endoscopic videos. Next round starts February 16, so sign up now to sharpen your skills! 🧠 www.asge.org/home/educati... #GISky #MedSky
links semaglutide to rare eye disorder NAION (vision loss risk)
⚠️ 65% quit within a year & weight often rebounds
They’re still relatively new, so long-term effects remain unknown.
www.sciencefocus.com/the-human-bo... #NurseSky #IMSky #SciSky #GISky #ozempic
Phase 1 results highlight SOR102, an oral bispecific TNF/IL-23p19 inhibitor, as a potential new therapy for #UlcerativeColitis. The first-in-human trial showed favorable safety and higher clinical response and remission rates vs placebo. #GISky #IBDSky
IL-23 is a key driver of chronic inflammation across the gut-skin-joint axis, transforming #InflammatoryBowelDisease care. IL-23 targeted therapy show durable efficacy, mucosal healing, and favorable safety, supporting earlier use in IBD treatment. #IBDSky #GISky
AGA Update on Inpatient Mgmt of Adults with IBD
🤔Good summary, with nice graphics (see below)
🤔Another reminder re prophylactic anticoags
🤔Early use of IV steroids, and if no response consider additional meds.
🤔Review on dealing with abscesses and peri-rectal disease.
#IMsky #Medsky #GIsky
Nearly 20% of patients hospitalized with #UlcerativeColitis required #colectomy within 1 year despite #infliximab, underscoring the importance of early risk stratification and timely escalation of care in high-risk ASUC.
#IBDSky #GISky
New in @bmj.com: "Higher habitual meat intake was associated with increased risk of objective flare in ulcerative colitis. #colitis #ulcerativecolitis #gastroenterology #GIsky #medsky #meat
gut.bmj.com/content/earl...
