#GeographicAtrophy

Simon J. Clark

@prof-clark.bsky.social

1 month ago

Linking the microbiome to the complement system in geographic atrophy - PubMed Age-related macular degeneration (AMD) is the leading cause of vision loss in the aged population with the late stage geographic atrophy (GA). Risk factors for AMD include age, genetic variants in…

New study links gut microbiome function, not composition, to complement dysregulation and genetic risk in geographic atrophy, highlighting a systemic gut/immune/retina axis. #GeographicAtrophy #AMD #Microbiome #Genomics #Ophthalmology #Science buff.ly/7yU87jB

Simon J. Clark

@prof-clark.bsky.social

1 month ago

Exploring Trial Endpoints in Geographic Atrophy Based on Localized Functional Changes in Microperimetry and AI-Quantified OCT Biomarkers - PubMed A significant association between RS in MP and EZ and RPE loss on OCT was established using DL. A reliable quantitative structure/function association provides the base for developing functional…

New study shows combining microperimetry with AI-quantified OCT biomarkers captures localized functional loss in geographic atrophy—pointing to more sensitive clinical trial endpoints. #GeographicAtrophy #AMD #Ophthalmology #AIinMedicine #ClinicalTrials buff.ly/DuHs30i

pharmaphorum

@pharmaphorum.bsky.social

1 month ago

Ocugen shares fall, despite positive eye disorder trial A trial of Ocugen's gene therapy for sight-robbing disease geographic atrophy (GA) showed efficacy – but still sparked a selloff in its shares.

A midstage trial of #Ocugen's #genetherapy for sight-robbing disease #geographicatrophy (GA) showed efficacy – but still sparked a selloff in its #stock.

pharmaphorum.com/news/ocugen-...

Simon J. Clark

@prof-clark.bsky.social

2 months ago

Ocugen posts midphase gene therapy data, charting course for rivalry with Apellis, Astellas Ocugen has reported preliminary phase 2 data on its e | Ocugen has reported preliminary phase 2 data on its eye disease gene therapy, providing more evidence that the candidate may outperform…

Prelim Phase 2 data hint Ocugen’s AAV5 gene therapy (OCU410) may outperform approved GA treatments at mid-dose, while higher doses raise intriguing biology questions 👀🧬 #GeneTherapy #DryAMD #GeographicAtrophy #Biotech #ClinicalTrials

@yuvip.bsky.social

3 months ago

Geographic Atrophy Market Size, Share, Trends, Report 2035 The Geographic Atrophy (GA) Market is projected to register a CAGR of 7.5% to reach USD 51.39 billion by the end of 2035 due to growing geriatric population.

👁️ Geographic Atrophy Market – advanced retina care: www.marketresearchfuture.com/reports/geog... #GeographicAtrophy #RetinaCare

Simon J. Clark

@prof-clark.bsky.social

6 months ago

Real-World Experience with Intravitreal Pegcetacoplan for the Treatment of Geographic Atrophy in Age-Related Macular Degeneration - PubMed Eyes treated with pegcetacoplan after 1 year had a 37% reduction in GA growth rate compared with their prior annual growth rate. Pegcetacoplan slowed the growth for foveal and non-foveal GA at a…

New real-world data show avacincaptad pegol (Izervay) is safe in GA, with no inflammation or endophthalmitis and only ~6% annual CNV risk—reassuring results beyond clinical trials.

#GeographicAtrophy #AvacincaptadPegol #Ophthalmology #RealWorldEvidence #Innovation buff.ly/mSnVtjg

Healio Clinical Guidance

@healioguidance.bsky.social

6 months ago

🤔What's the best thing about our module on geographic atrophy? 👇
www.healio.com/clinical-gui...

Hear Dr. David A. Eichenbaum's response!
#geographicatrophy #Ophthalmology

Healio Clinical Guidance

@healioguidance.bsky.social

6 months ago

👁️ What you need to know about geographic atrophy is at 👇
www.healio.com/clinical-gui...

#geographicatrophy #eyecare

Ophthalmology Management

@ophthalmologymg.bsky.social

6 months ago

OM Author Insights: New Hope for GA Patients Vitreoretinal surgeons Dr. Sunir Garg and Dr. Sidra Zafar discuss exciting innovations in GA treatment. Read more about these in their article, "Rapid Developments in Geographic Atrophy."

Vitreoretinal surgeons Dr. Sunir Garg and Dr. Sidra Zafar, Wills Eye Hospital, discuss exciting innovations in geographic atrophy treatment. Watch the video here: ophthalmologymanagement.com/issues/2025/....
@willseye.bsky.social‬ #geographicatrophy

Ophthalmology Management

@ophthalmologymg.bsky.social

7 months ago

Flip through the pages of this month’s digital edition of Ophthalmology Management: digital.ophthalmologymanagement.com/publication/...

#retina #retinal #retinaldisease #homemonitoring #RemotePatientMonitoring #optogenetics #geographicatrophy #privateequity #ophthalmology #youngophthalmologists

Ophthalmology Management

@ophthalmologymg.bsky.social

7 months ago

The current and emerging geographic atrophy treatments offer hope to affected patients and demonstrate rapid, ongoing innovation in this field. Learn more here: ophthalmologymanagement.com/issues/2025/... @willseye.bsky.social #geographicatrophy #ophthalmologist #ophthalmology

Ophthalmology Management

@ophthalmologymg.bsky.social

7 months ago

Here’s a glimpse at what’s in our latest issue! Be sure to read the full issue here: digital.ophthalmologymanagement.com/publication/....

#retina #retinal #retinaldisease #homemonitoring #RemotePatientMonitoring #optogenetics #geographicatrophy #ophthalmology #youngophthalmologists

pharmaphorum

@pharmaphorum.bsky.social

7 months ago

#Sanofi has been granted a speedy review from the #FDA for a gene therapy for #geographicatrophy (GA), a complication of #agerelatedmaculardegeneration (AMD), as it prepares to test it in a clinical trial.

pharmaphorum.com/news/fda-fas...

40:40 Recruitment - celia@4040recruitment.co.uk

@4040rec.bsky.social

8 months ago

First patient dosed in trial for novel dry AMD treatment PST-611 - PharmaTimes PulseSight begins phase 1 safety study of gene therapy for geographic atrophy

#Ophthalmology #clinicaltrial #dryAMDtreatment #PST611 #PulseSightTherapeutics #phase1safetystudy #genetherapy #geographicatrophy #GA #nonviralgenetherapy #dryagerelatedmaculardegeneration #AMD #DryAMD #PST611CT1study #electrotransfectiontechnology #DNAplasmids
pharmatimes.com/news/first-p...

@retinaint.bsky.social

9 months ago

@avrilbdaly.bsky.social @nabinpaudel.bsky.social @unibonn.bsky.social @ema.europa.eu

#GeographicAtrophy #ClinicalTrials

@retinaint.bsky.social

9 months ago

Our @arvoinfo.bsky.social #SIG on GA trial endpoints is today. Join global experts + patient voices to rethink what meaningful outcomes look like.
Last chance to register! www.arvo.org/education/sp...
@avrilbdaly.bsky.social @nabinpaudel.bsky.social #GeographicAtrophy #ClinicalTrials

Tonny Johnson

@tonnyjohnson.bsky.social

9 months ago

Translational Gene Therapy Breakthroughs for Inherited and Acquired Blindness Discover advanced gene therapy strategies for blindness at ASGCT 2025, featuring innovative cell based assays and transformative treatments for inherited vision loss.

Translational Gene Therapy Breakthroughs for Inherited and Acquired Blindness

#blindness #RetinitisPigmentosa #StargardtDisease, #UsherSyndrome #LeberCongenitalAmaurosis #LCA #glaucoma #GeographicAtrophy #MacularDegeneration #genetherapy
www.marinbio.com/from-bench-t...

@retinaint.bsky.social

9 months ago

A yellow poster with details of the SIG session: Special Interest Group (SIG). Harmonizing and Designing Novel Endpoints in Degenerative Retinal Diseases to Foster Innovation. June 10 - 9:00 - 10:30 am EDT

Our @arvoinfo.bsky.social #SIG on #GeographicAtrophy endpoints is just 2 weeks away. Join us on June 10 to help shape more meaningful trial outcomes.
🔗 Register today! www.arvo.org/education/sp...
@avrilbdaly.bsky.social @nabinpaudel.bsky.social @ema.europa.eu #GeographicAtrophy #ClinicalTrials

@retinaint.bsky.social

9 months ago

Blue poster with dark grey text: Special Interest Group (SIG). Harmonizing and Designing Novel Endpoints in Degenerative Retinal Diseases to Foster Innovation. #ARVO2025. The Retina International logo is centred at the bottom of the graphic.

Image 2: Dark grey poster with blue text. Panelists: Avril Daly, Dr. Andrew Want,Dr. Maximilian Pfau, Dr. Jane Moseley

How do we make GA clinical trials more patient-focused?
Join our virtual @arvoinfo.bsky.social SIG session:

June 10, 9-10:30am EDT.

Hosted by @retinaint.bsky.social - open discussion encouraged!

🔗 Register: www.arvo.org/education/sp...

#GeographicAtrophy #RetinaResearch #ClinicalTrials #AMD

Wisdom4you

@wisdom4you.bsky.social

10 months ago

Stay Social With Vision Impairment From Geographic Atrophy Geographic atrophy can lead to vision impairment and cause social isolation. Here’s how to stay connected with your loved ones and feel less alone.

Learn more about Geographic Atrophy by reading this article:
www.everydayhealth.com/eye-vision-h...
#GeographicAtrophy #EyeHealth #VisionLoss #MacularDegeneration #AMD

Ysios Capital Partners

@ysioscapital.bsky.social

10 months ago

#PortfolioNews | #SparingVision receives #FDA support to launch Phase II trial of SPVN06 in #GeographicAtrophy

🎯 #GA is an advanced form of dry age-related macular degeneration (dAMD) that leads to progressive and irreversible vision loss

👉 buff.ly/m0BlGti

#GeneTherapy

Medical Ophthalmology Society UK

@mosuknews.bsky.social

1 year ago

The future will be fascinating...

Meeting almost coming to a close, thank you to all our speakers, delegates and everyone involved in this meeting #AMD #GeographicAtrophy

Ophthalmology Management

@ophthalmologymg.bsky.social

1 year ago

The FDA approved an expanded label for Izervay (avacincaptad pegol intravitreal solution; Astellas Pharma), removing limitations on treatment duration for GA secondary to AMD. Click here to learn more: ophthalmologymanagement.com/news/2025/fd...

@astellaspharma.bsky.social #AMD #geographicatrophy

𝕄𝕣 ℂ𝕠𝕟𝕤𝕡𝕚𝕣𝕒𝕔𝕪 3️⃣3️⃣ 🕉️

@mrconspiracy33.bsky.social

1 year ago

🔔 $APLS - EDUCATIONAL 🔔
A SNEAK PEAK TO HOW #MRC 👁️ THIS REALITY & HOW EVERYTHING IS CONNECTED 🪄

APLS = SLAP = LAPS = PALS 👀

APE-LLIS PHARMACEUTICAL = APE 🦍

DISCLAIMER: THIS IS NOT INVESTMENT ADVICE❗️
👁️ #MRC33 👁️

#Biotech #GeographicAtrophy #StockMarket #TruthSeeker #Conspiracy #Finance #Stocks