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Posts tagged #Gliomas

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Traces of bacteria inside brain tumors may affect tumor behavior Researchers at The University of Texas MD Anderson Cancer Center have uncovered unexpected traces of bacteria within brain tumors. This discovery offers new insights into the environment in which…

Traces of #bacteria inside #brain tumors may affect #tumor behavior ...

| #microbes | #cancer | #gliomas | #Oncology | By @mdanderson.bsky.social via @sciencex.bsky.social

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#Article in #MedComm_Oncology

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience doi.org/10.1002/mog2...

#cancer #CancerNeuroscience #gliomas #NeurodegenerativeDisease #PD #Therapeutic #Neuroscience

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"...The visible effects of #HERV reactivation are associated with diseases like #multiple sclerosis (MS), certain cancers (such as #gliomas), and infectious diseases like #AIDS and #COVID-19.(...)"

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Please reach out if you'd like to learn more or help us amplify this important resource for patients and their care teams.

#cancerresearch #clinicaltrials #cancer #braincancer #GBM #gliomas #meningioma #medulloblastoma

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World-first clinical trial reveals unprecedented insights into brain cancer treatment Victorian brain cancer researchers have achieved a global-first, using an innovative process to learn how a new drug suppresses tumour activity and provides hope to patients with low-grade gliomas (LG...

World-first trial brings new hope for brain cancer patients. Using the pioneering BrainPOP platform, researchers reveal how a novel drug suppresses #tumour activity in low-grade #gliomas. A major leap in treatment innovation. #TCSC #braincancer #BrainPOP

www.wehi.edu.au/news/world-f...

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Point/counterpoint: Upfront BRAF inhibition for adult BRAF-mutant high-grade gliomas Gliomas classified as CNS WHO grade 3 and 4 (herein referred to as HGG) are aggressive, fast-growing tumors with a poor prognosis and limited therapeutic o

Happy to share our collaborative Point/Counterpoint article on upfront #BRAF inhibition for adult high-grade #gliomas - a summary of the first joint SNO/EANO Young Investigators debate at #SNO2024. @marjoleingeurts.bsky.social @mjlimfat.bsky.social doi.org/10.1093/neuo...

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UP Oncolytics Receives Matching Grant to Boost Brain Cancer Therapy Innovations UP Oncolytics secures a $75,000 matching grant to advance research on oncolytic virus therapy for gliomas, focusing on innovative solutions for brain cancer treatment.

UP Oncolytics Receives Matching Grant to Boost Brain Cancer Therapy Innovations #United_States #Gliomas #Milwaukee #Rosalind_Franklin #UP_Oncolytics

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Investigating Associations Between Prognostic Factors in Gliomas: Unsupervised Multiple Correspondence Analysis Background: Multiple Correspondence Analysis (MCA) is an unsupervised data science methodology that aims to identify and represent associations between categorical variables. Gliomas are an aggressive type of cancer characterized by diverse molecular and clinical features that serve as key prognostic factors. Thus, advanced computational approaches are essential to enhance analysis and interpretation of the associations between clinical and molecular features in gliomas. Objective: This study aims to apply MCA to identify associations between glioma prognostic factors and also explore their associations with stemness phenotype. Methods: Clinical and molecular data from 448 brain tumor patients were obtained from The Cancer Genome Atlas (TCGA). The mDNA stemness index, derived from DNA methylation patterns, was built using a one-class logistic regression (OCLR). Associations between variables were evaluated using the chi-square test with k degrees of freedom, followed by analysis of the adjusted standardized residuals. MCA was employed to uncover associations between glioma prognostic factors and stemness. Results: Our analysis revealed significant associations among molecular and clinical characteristics in gliomas. Additionally, we demonstrated the capability of MCA to identify associations between stemness and these prognostic factors. Our results exhibited a strong association between higher mDNA stemness index and features related to poorer prognosis, demonstrating the utility of MCA as an analytical tool for elucidating potential prognostic factors. Conclusions: MCA proves to be a valuable tool for understanding the complex interdependence of prognostic markers in gliomas. MCA facilitates the exploration of large-scale datasets and enhances the identification of significant associations.

Investigating Associations Between Prognostic Factors in Gliomas: Unsupervised Multiple Correspondence Analysis #Gliomas #CancerResearch #DataScience #MolecularBiology #Bioinformatics

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Representative axial plane MRI and FET-PET imaging of gliomas in adults.

Representative axial plane MRI and FET-PET imaging of gliomas in adults.

MRI is essential for diagnosis of #gliomas and other types of brain #tumour. https://www.nature.c

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@ucsfci2.bsky.social authors, including Dr. Jeff Rudie, developed one of the most extensive & comprehensively annotated publicly available datasets for post-treatment #gliomas.

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Liquid biopsies for the monitoring of gliomas and brain metastases in adults Liquid biopsies have emerged as a promising candidate for minimally invasive, accurate, and affordable monitoring of disease progression and treatment response in gliomas and brain metastases.

Liquid biopsies have emerged as a promising candidate for minimally invasive, accurate, & affordable monitoring of disease progression & treatment response in #gliomas & brain #metastases.

Find out more in this #EdsChoice review👉 buff.ly/F0KwOcf

#NeuroSky #OncSky #Glioma

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Member of CHRI's Pediatric Cancer Research Group, Chittalsinh Raulji, MBBS, recently received funding for a trial of DAY101 #monotherapy for #gliomas and for a study of concizumab prophylaxiss treatment of patients with #haemophilia A or B. Excited to see the results!

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⚡My new image🥼🔍 🌈
#Gliomas are deadly brain tumors that suppress the #immune_system, making them hard to treat. Authors uncovered four immune programs: two unique to #brain_tumors + two shared with other #cancers. These patterns aren’t based on cell type but are driven by the #tumor_environment!

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Investigating Associations Between Prognostic Factors in Gliomas: Unsupervised Multiple Correspondence Analysis Background: Multiple Correspondence Analysis (MCA) is an unsupervised data science methodology that aims to identify and represent associations between categorical variables. Gliomas are an aggressive type of cancer characterized by diverse molecular and…

Investigating Associations Between Prognostic Factors in Gliomas: Unsupervised Multiple Correspondence Analysis #Gliomas #CancerResearch #PrognosticFactors #DataScience #MultipleCorrespondenceAnalysis

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Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood–brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas AbstractBackground. Glioblastoma is a highly aggressive brain cancer that is resistant to conventional immunotherapy strategies. Botensilimab, an Fc-enhanc

🗞 A team of our researchers and collaborators including Kwang-Soo Kim and Adam Sonabend from @nufeinbergmed.bsky.social and Dhan Chand from Agenus, in partnership with Carthera, published an article in Neuro-Oncology

Full study👇
academic.oup.com/neuro-oncolo...
#oncology #neurology #gliomas

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Text: new study suggests no link between common brain malignancy and hormone therapy. Logo of the menopause society. text reading leading the conversation.

Text: new study suggests no link between common brain malignancy and hormone therapy. Logo of the menopause society. text reading leading the conversation.

A new study suggests there is no link between #hormonetherapy and common #braintumors known as #gliomas. Despite no association, women are still six times more likely to develop gliomas in the brain than men. @MenopauseJrnl

Learn more here: tinyurl.com/8cu39mcs

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Lindonlight Collective on LinkedIn: #pediatriccancerresearch #braincancer #preclinicalmodels #researchfunding… 🌟 Advancing Pediatric Brain Cancer Research 🌟 We are proud to announce that Lindonlight Collective has awarded $1.97 million to Dr. Petra Hamerlik at the…

Huge congrats to our Chair of Translational Neuro-Oncology Prof Hamerlik for this important @lindonlight.bsky.social award allowing the interdisciplinary team to advance understanding and future treatment options for childhood brain tumours.

#PediatricCancerResearch #gliomas

shorturl.at/EXFnS

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Research Postdoctoral Fellow Click the link provided to see the complete job description.

We are #hiring a #Bioinformatics postdoctoral fellow within the #Brain #Tumor Institute at Children's National Hospital to work on a large international study of NF1 #pediatric #gliomas. Check out the posting below and contact me if interested! cnhs.taleo.net/careersectio...

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Why do gliomas tend to recur in the brain? — Harvard Gazette In an effort to understand what drives growth and recurrence of gliomas, researchers provide the first profile of the neurons that connect to them.

Why do #gliomas tend to recur in the #brain? news.harvard.edu/gazette/stor...

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Alpheus Medical's Breakthrough Therapy Shows Promising Results for High-Grade Gliomas Alpheus Medical, Inc. reports significant Phase 1/2 trial results revealing that its innovative therapy doubles survival rates for high-grade glioma patients.

Alpheus Medical's Breakthrough Therapy Shows Promising Results for High-Grade Gliomas #United_States #Alpheus_Medical #Sonodynamic_Therapy #Gliomas #Chanhassen

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MDADI MDADI

📣 Happening Today at #SNO2024! Join Drs. Manmeet Ahluwalia & Patrick Wen for a live #IDH-Mutant #Gliomas symposium.
🕔 5:15 PM CST (Reg & Dinner) | 5:30 PM CST (In-Person or 💻)
📍 Room 332
Partnered with the American Brain Tumor Association. See you there! 🔗 PeerView.com/2024Glioma

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MDADI MDADI

🚨 Don’t miss our symposium tomorrow at #SNO2024! Join Drs. Ahluwalia & Wen for expert insights on #IDH-mutated #gliomas, #biomarker testing, & #targetedtherapy.
💻 PeerView.com/2024Glioma
🕔 5:15 PM CST (Reg & Dinner 🍽️) | 5:30 PM CST (Symposium)
📍 Room 332, Houston Convention Center & Virtual

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Mass-spec and IMC give deep insights into tumors Thanks to the use of highly advanced techniques, researchers at Leiden University Medical Center (LUMC) have succeeded in penetrating deeper into tumors than ever before.

🧠 Scientists at the 🇨🇭 University of Geneva (UNIGE) and the 🇨🇭 Geneva University Hospitals (HUG) have developed CAR-T cells capable of targeting malignant #gliomas while preserving healthy tissue. #glioblastoma #braincancer #immunotherapy

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Advancing Brain Tumor Vaccines: Michael Platten's Immunotherapy Innovations Michael Platten: Breaking the Wall of Brain Tumor Vaccines

Michael Platten is pioneering vaccines targeting gliomas by harnessing the patient's immune system to combat cancer-causing mutations. #neuroscience #gliomas #braintumors #vaccines

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EU funding for pioneering research on the treatment of #gliomas: Establishing direct light therapy to combat #brain tumors / @EUeic supports the international collaboration with EUR 2.2 million in its #EICPathfinder program...

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Really looking forward to starting our #nhmrc ideas grant with our wonderful collaborators @Theo_BrainC_lab @WBoesmans @gmatteoli1978 and David Wilson III looking at how #enteric #glia are protected from developing #gliomas! Can't wait to get experiments on the way!!!

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