Latest posts tagged with #biomarker on Bluesky
Metabolic marker profiling of circulating tumour cells in NSCLC patients treated with osimertinib: focus on MCT1 and MCT4
@tamedoncol.bsky.social
@journals.sagepub.com
journals.sagepub.com/doi/10.1177/...
#biomarker #cancerprognosis #lungcancer #oncology #openaccess
Biovica Q3 Earnings call #biovicb #investors #oncology#biomarker #pharma #breastcancer
Register for our upcoming Q3 Earnings call taking place:
Wednesday 18th March, 2025 at 15:00 CET.
Register here: http://bit.ly/4rqjH3I
Presenters are:
Anders Rylander, CEO
Anders Morén, CFO
#biovicb #investors #biomarker #pharma
Neto & Pinho show that grip force variability analyzed with #deeplearning can serve as a novel #biomarker to accurately distinguish mid-stage #Parkinson's disease patients from healthy older adults. doi.org/10.1016/j.ne... #MachineLearning #NeuroMarkers #Neurology #MedSky #neuroskyence
Kidney Injury #Urine #Biomarker Normal Ranges in #Children
#VisualAbstract by Susan Thanabalasingam
www.kireports.org/article/S2468-0249(26)02...
Now published: Elevated blood p-tau 181 and 217 levels are not specific to Alzheimer´s disease and may also serve as a diagnostic tool of ATTR and AL amyloidosis! #alzheimer #biomarker. Wonderful collaboration with 3 European amyloid centers. @natmed.nature.com doi.org/10.1038/s415...
1/4
When do #HealthGaps between rich and poor really begin? New #biomarker research from the Netherlands reveals a surprising and troubling answer.
High-resolution retinal imaging reveals immune cell infiltrates in the inner retina of MS patients, particularly after optic neuritis. These cells may serve as early, non-invasive biomarkers of neuroinflammation 👉 buff.ly/QH2t3yh
#MS #OpticNeuritis #Biomarker
Measured in #bloodsamples, the #biomarker #p-tau217 was strongly linked to future #dementia risk across decades of follow-up in a large, diverse cohort of U.S. women
@ucsdmedschool.bsky.social @UCSDPharmacy
GPR54 promotes progression & #MetabolicReprogramming in #NSCLC by enhancing dopa decarboxylase expression via the Gαq/11/PI3K/AKT/mTOR signaling pathway, underscoring its potential as both a #Biomarker & #TherapeuticTarget.
#OpenAccess: doi.org/10.1038/s413...
This study identified PDCD2 as a prognostic #Biomarker in #Glioma, showing that its overexpression promotes tumor progression and correlates with malignancy & poor survival, marking it as a potential #TherapeuticTarget.
#OpenAccess: doi.org/10.1016/j.ge...
Online now:Dark white matter is a subcortical MRI marker in seizures and systemic disorders: A narrative review. doi.org/10.1016/j.ne... #DarkWhiteMatter #Neuroimaging #Epilepsy #MRI #Seizures #MOGAD #Neurology #Biomarker #MedicalResearch #BrainMRI #StatusEpilepticus #MedSky #neuroskyence
A #common #biomarker of #schizophrenia and #bipolar #disorder revealed
Research reveals schizophrenia and bipolar disorder share white matter changes in the corpus callosum. This supports a shared "psychosis spectrum" rather than distinct illnesses scitechupdates.com/a...
In our #Oncology Data Analysis Demo Report, we demonstrate how applying #bioinformatics to a clinical #oncology study revealed pivotal insights from complex #biomarker data. Download the report now ⬇️:
fiosgenomics.hubspotpagebuilder.com/download-your-free-demo-...
The techniques for diagnosing #REMSleepBehaviorDisorder remain limited. #REM #sleepmicrostructures could at as a #biomarker for diagnosing #RBD.
academic.oup.com/sleep/articl...
In our #Oncology Data Analysis Demo Report, we demonstrate how applying #bioinformatics to a clinical #oncology study revealed pivotal insights from complex #biomarker data. Download the report now ⬇️:
fiosgenomics.hubspotpagebuilder.com/download-your-free-demo-...
Rethinking how we assess donor kidney viability. Ex vivo machine perfusion allows dynamic organ evaluation but traditional in vivo biomarkers fall short in this setting. #Transplantation #TXPforAll #Biomarker tinyurl.com/5bjkrvza
#Biomarker validation is crucial, misuse can lead to false results and poor outcomes.
Learn more about biomarkers validation in our blog: www.fiosgenomics.com/biomarker-validation-avo...
#bioinformatics #drugdevelopment
Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint: A Retrospective Analysis
#NeoadjuvantChemotherapy in #Osteosarcoma elevates #SerumLipids (TC, TG, ApoB, LDL-C, ApoE); pretreatment levels show no prognostic value, but rising Lp(a) correlates with Ki-67, hinting at a potential #biomarker for outcomes.
Read: doi.org/10.1007/s115...
Long-read #transcriptomics of #GallbladderCancer uncovered ERBB2 i14e, a splice isoform linked to poor prognosis and #trastuzumab resistance; #antisense targeting restored sensitivity, revealing a potential #biomarker and therapeutic strategy.
#STTT: doi.org/10.1038/s413...
#Bauchspeicheldrüsenkrebs wird meist erst spät diagnostiziert, weil er zunächst keine Beschwerden verursacht. Ein von Forschern der @uniulm.bsky.social neuentdeckter #Biomarker könnte den #Krebs bereits in seiner Entstehungsphase erkennen. #Pankreaskarzinom
Host-derived FSTL1 potentiates Ly6C+ monocytes /macrophages recruitment via the CD14/TLR4/NF-κB axis to modulate the hepatic #Fibrotic #ImmuneMicroenvironment, serving as a key #Biomarker for #MesenchymalStemCell therapy outcomes.
#STTT #OpenAccess: doi.org/10.1038/s413...
Scientists report that limited #TACE-induced #necrosis predicts post-transplant #HepatocellularCarcinoma recurrence, revealing a hypoxia-driven HIF-1α/LGR5/MAPK axis that boosts metastasis & positions #LGR5 as a key #biomarker and therapeutic target.
#OpenAccess: doi.org/10.1016/j.ge...
Want to boost the success of your preclinical development plan?
From target identification to #biomarker discovery, find out how bioinformatics can help at each stage of the #preclinical development:
www.fiosgenomics.com/optimise-your-preclinica...
pubmed.ncbi.nlm.nih.gov/41697443/
"41 #biomarker differences identified between young patients and healthy controls. Markers aligned with reported symptoms across organ systems, supporting physiological basis for pediatric #longCOVID in scoping review of 9 studies."
OncoHost's New Study Bridges Serum and Plasma Proteomics for Enhanced Biomarker Discovery #Israel #OncoHost #PROphet #Binyamina #Biomarker
#HepatitisBvirus core protein stability is sustained by host factor PSME1, which prevents HBc degradation via the #26Sproteasome; silencing PSME1 reduces HBc levels & HBV transcription, identifying PSME1 as a novel #biomarker for chronic #HBV.
#OpenAccess: doi.org/10.1016/j.ge...
Last chance for 20% off B10 & B50 until 20.02.26
Capitainer®B #driedbloodspot sampling card is a quantitative #microsampling technology for research & clinical #diagnostics Precise as pipetting enhancing accuracy of remote disease #biomarker detection or #serology testing
tinyurl.com/yxx62uwe
Targeting AKR1B1 inhibits metabolic reprogramming to reverse systemic therapy resistance in hepatocellular carcinoma
AKR1B1-driven #MetabolicReprogramming sustains #DrugResistance in #HCC, while #epalrestat restores sensitivity—positioning AKR1B1 as both #biomarker and therapeutic target to overcome systemic resistance. @tsinghuauniversity.bsky.social
#STTT: doi.org/10.1038/s413...
New in #Biomarker Research! 💡
Southern Medical University scientists demonstrate that FuNVCAR, a T cell-targeted nanovesicle system, enables functional in vivo #CAR-T cell generation and sustained disease modification in experimental #arthritis.
🆕 https://bit.ly/4aumGSi
Exciting news!
Once more we will be participating at #AAICNeuro in Manchester & online!
This year, Dr. @marcsuarezcalvet.bsky.social will be giving an oral presentation at a plenary session on #biomarker advancements in dementia diagnosis.
