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Differentiating IL-23 Inhibitors in Crohn’s Disease An overview of agents targeting the IL-23 pathway in Crohn’s disease. Understand their similarities and differences, key phase 3 and head-to-head trials, and their positioning as a Crohn's disease…

Understand their similarities and differences of agents targeting the IL-23 pathway in #CrohnsDisease.

Discover the key phase 3 and head-to-head trials, and their positioning as a Crohn's disease treatment, with this #EdsChoice review.

👉https://buff.ly/qgRoA1H

#GastroSky #MedSky #IL23

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TREMFYA® (guselkumab) TREMFYA® (guselkumab) Official Consumer Website. See full Prescribing & Safety Information.

TREMFYA (guselkumab)

www.tremfya.com

"It works by blocking interleukin-23 (IL-23), a protein involved in inflammation and the immune response in these conditions." #IL23

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An interleukin-23- interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis While commensal flora is involved in the regulation of immunity, the interplay between cytokine signaling and microbiota in atherosclerosis remains unknown. We found that interleukin (IL)-23 and its d...

An interleukin-23- interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis #IL23 #IL22 #MECFS #LongCovi

pmc.ncbi.nlm.nih.gov/articles/PMC...

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Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis - PubMed Intestinal fibrosis is an excessive proliferation of myofibroblasts and deposition of collagen, a condition frequently seen in Crohn's disease (CD). The mechanism underlying myofibroblast hyper-prolif...

Induction of autophagy in Cx3cr1+ mononuclear cells limits #IL23 / #IL22 axis-mediated intestinal fibrosis #MECFS #LongCovid

pubmed.ncbi.nlm.nih.gov/30765845/

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