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#LED3Symposium

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Posts tagged #LED3Symposium

Excited to be part of the @led3hub.bsky.social of @leidenscience.bsky.social and of the organizing committee of the #LED3Lectures and #LED3Symposium. I am convinced that these are amazing initiatives that strengthen our collaborative spirit. New exciting activities are coming in 2026 and 2027.

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We are happy that we could continue our activities to bring our researchers closer together including the LED3 PhD/Postdoc Symposium #LED3Symposium and our flagship #LED3Lectures, in which we heard talks by a diverse selection of world-leading speakers in the field of #DrugDiscovery. (2/3)

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I had a blast at the #LED3Symposium. I learned many new things about the exciting and diverse research that is going on in our @led3hub.bsky.social.
A huge thank you to our PhD organizers, @pasteldemata.bsky.social, Inês Justo, Filipe Cruz, Gianluca Turco and Evangelina Geets for making it possible.

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Congratulations to the winners of the awards at the #LED3Symposium!

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As the #LED3Symposium came to an end, we were excited to be able to recognize the most outstanding contributions to the event.
Congratulations to Laurence Cleenewerk (best talk award), Asina Gijasi (best flash talk award) and Thanasis Patsos (best poster award).

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The #LED3Symposium was a very successful event with a lot of amazing science and many interdisciplinary interactions.
A huge thanks to our organizers @pasteldemata.bsky.social, Inês Justo, Filipe Cruz, Gianluca Turco, Evangelina Geets, @sebastianpomplun.bsky.social and @stephanhacker2.bsky.social.

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Was great showing our work on single molecule analysis of aptamer-protein interactions at the #LED3Symposium

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Interesting talk by @mikefilius.bsky.social at the #LED3Symposium. He talked about his research on an assay using single molecule FRET measured by total internal reflection fluorescence microscopy to characterize aptamer-protein binding kinetics www.science.org/doi/10.1126/...
#ChemBio #Biochemistry

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Amazing talk by @seanmckenna.bsky.social at the #LED3Symposium. He talked about his research on virtual screening (docking, pharmacophore modelling) of large libraries of compounds that can be made combinatorially from in-stock starting materials for rapid hit validation on the example of CCR2.

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The second #FlashTalk session at #LED3Symposium was another firework of diverse early #DrugDiscovery topics including β-lactamase evolution (Cristina López Gallego), EC50 determinations (Chenyu Wang), transcription factor inhibitors (Brecht Ellenbroek) and natural products discovery (Pavlo Hrab).

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Exciting talk by Max Kloet from the group of Gerbrand van der Heden van Noort from the LUMC at the #LED3Symposium. He talked about his research into the interplay of the posttranslational modifications of ubiquitination and ADP-ribosylation. www.biorxiv.org/content/10.1...

#PTMs #ChemBio

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Interesting talk by Xuanlin Liu from the groups of @annegretemartson.bsky.social and @cvhasselt.bsky.social at the #LED3Symposium. She talked about her work on characterizing the viral load during Cytomegalovirus (CMV) infections using PCR and TCID50 to build models for efficiency predictions.

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Great talk by Mirjam Huizenga from the group of @mvdstelt.bsky.social at the #LED3Symposium. She talked about her doctoral research into inhibiting monoacylglycerol lipase (MAGL) for the treatment of chemotherapy-induced peripheral neuropathy. www.nature.com/articles/s41...

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Lunch time was also the time for the group photo and the #PosterSession at the #LED3Symposium. Great to see so many people that are excited about early drug discovery coming together and exchanging over the posters. We hope that this sparked many new interdisciplinary ideas and collaborations.

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The first #FlashTalk session of the #LED3Symposium gave us insights into early #PKPD modelling for predicting the outcome of clinical studies for #tuberculosis treatment (Asina Gijasi) and into self-encoded libraries for affinity-selection MS of macrocyclic compounds (cycloSELs, Miguel Mata).

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Interesting talk by Laurence Cleenewerk from the groups of Joen Luirink and Nathaniel Martin at the #LED3Symposium. She talked about her research on screening natural product extracts for compounds that selectively target components in the cell envelope of Gram-negative bacteria.

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Interesting talk by Edith van der Nol from the group of @sebastianpomplun.bsky.social at the #LED3Symposium. She talked about her doctoral research into barcode-free, self-encoded libraries (SELs) for the discovery of protein binders using affinity-selection MS. chemrxiv.org/engage/chemr...

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Great talk by Tessa Gote at the #LED3Symposium on her doctoral research in the @armstrongchembio.bsky.social group. She talked about inhibitors for sialic acid esterases with potential for combating infectious diseases. Exciting insights into #Biochemistry, #Microbiology and #StructuralBiology.

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Inspiring keynote lecture by NVBMB Speaker of the Year Jennifer Lippincott-Schwartz at the #LED3Symposium. She talked about studying molecular interactions and dynamics in the cell on the single molecule level using cryo-EM and super-resolution microscopy. www.sciencedirect.com/science/arti...

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The scientific program of the #LED3Symposium gets underway with an inspiring keynote lecture by NVBMB Speaker of the Year Jennifer Lippincott-Schwartz. She talked about her group's exciting contributions to imaging life's structures and their dynamics down to the atomic level.

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At the #LED3Symposium, @seanmckenna.bsky.social introduced the activities of the @youngscinet.bsky.social of the @euromedchem.bsky.social and their relevance for our LED3 society and overall early career researchers in the field.
Check out their activities here: www.efmc.info/ysn

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Inês Justo welcomes a full lecture hall to the #LED3Symposium, which was afterwards officially opened by the dean of @leidenscience.bsky.social, Jasper Knoester. He highlights the importance of interdisciplinary interactions, like fostered by LED3, for world-leading science.
#ChemBio #ChemSky

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Very excited for today's #LED3Symposium and looking forward to hearing about all the diverse science that is going on in the @led3hub.bsky.social directly from the early career researchers.

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We are about to get started with the 2nd LED3 PhD/postdoc symposium #LED3Symposium. We are looking forward to a full day of exciting science presented by the early career researchers of our network!
www.universiteitleiden.nl/en/science/l...

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@gillesvanwezel.bsky.social (at #LeidenBiology) on nonprofit drug discovery - from lab to international networks
-at @led3hub.bsky.social #LED3symposium

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Paola Picotti @ethzurich.bsky.social on Decoding the protein dance

#LED3symposium

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Preview
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag

Marnix highlights BGC mining, like the recent effort led by @mmzdouc.bsky.social and @kblin.bsky.social - MIBIG4 an international annotation effort

Published in #NAR
academic.oup.com/nar/article/...

#LED3symposium

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@marnixmedema.bsky.social on Omics-based prioritisation of natural product chemical space for drug discovery
-at #LED3symposium

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Amazing story by Paul Jensen in in situ isolation and identification of novel natural products
#LED3symposium
See their @naturecomms.bsky.social paper 👇🏼
www.nature.com/articles/s41...

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Paul Jensen on changing paradigms in natural product discovery: a molecule to microbes approach
#LED3symposium

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