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#ChemBio

Latest posts tagged with #ChemBio on Bluesky

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Posts tagged #ChemBio

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How can peptide-based drugs be modified at a late stage for further biological evaluation?

At #Lunteren2026, Eva Meeus told us about her amazing work on modifying the skeleton of tryptophan in peptides through nitrogen atom insertion.

pubs.acs.org/doi/abs/10.1...
#ChemSky #ChemBio #Peptide

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Activating prodrugs with an external stimulus is an exciting strategy in #DrugDiscovery.

Rienk Eelkema told us at #Lunteren2026 about using ionizing radiation as a trigger for prodrug activation with deep tissue penetration.

pubs.rsc.org/en/content/a...
#ChemSky #ChemBio #DrugDiscovery #Cancer

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Interesting talk by Peter Fodran from the University of Groningen at #Lunteren2026. He talked about his group's work on the efficient and #MedChem friendly synthesis of privileged scaffolds for drug discovery.

www.fodranlab.com
#ChemSky #ChemBio #DrugDiscovery #Synthesis

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Great talk by Phillip Yesley from the group of Wim Velema at #Lunteren2026.

He discussed the use of mutational profiling to find covalent ligands for structured #RNA using acyl imidazoles as the reactive group.

onlinelibrary.wiley.com/doi/10.1002/...
#ChemSky #ChemBio #Covalent #CovalentInhibitor

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Predicting the stereochemical outcome of glycosylations is a complex problem.

In his talk at #Lunteren2026, Daan Hoogers from the group of Jeroen Codee of our @led3hub.bsky.social presented his research into the systematic exploration of this question.
pubs.rsc.org/en/content/a...
#ChemSky #ChemBio

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Rachael Tiamiyu and Valentine Nwanelo at the American Society for Biochemistry and Molecular Biology conference

Rachael Tiamiyu and Valentine Nwanelo at the American Society for Biochemistry and Molecular Biology conference

Rachael Tiamiyu discussing her research poster at a conference

Rachael Tiamiyu discussing her research poster at a conference

Valentine Nwanelo standing next to his research poster

Valentine Nwanelo standing next to his research poster

Rachael Tiamiyu and Valentine Nwanelo, Pflum Lab members, representing WSU at the @asbmb.bsky.social (American Society for Biochemistry and Molecular Biology) conference! #wsuchemistry #ASBMB26 #ChemSky #chembio

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Great to hear the full story of this exciting project that is done in collaboration with, among others, @mads-chem.bsky.social of our @led3hub.bsky.social. (2/2)

#ChemBio #ChemSky #Synthesis #SAR #Tuberculosis #Virulence #ABPP #PAL

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Excellent #OrganicSynthesis is the basis of many #ChemBio projects. Nevertheless, we often do not present much of our synthesis.
I am excited to be at the Dutch Symposium on Organic Chemistry #Lunteren2026, where synthesis will take the center stage.
#ChemSky #OrganicChemistry #Science #Conference

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Getting started with a full week of #Science #conferences. I will be at #Lunteren2026 and #KNCVMCCB2026 by the #KNCV and at #Biochemistry2026 by @gdchbiochem.bsky.social. Looking forward to learning about exciting science and (re-)connecting with many scientists.
#ChemBio #Biochemistry #ChemSky

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An industrial automated laboratory for programmable protein evolution - Nature Chemical Engineering This study reports on an industrial-grade, large-scale, all-in-one integrated and automated laboratory (iAutoEvoLab), combined with a genetic circuit-controlled, growth-coupled continuous evolution sy...

In case you missed it!

An industrial-grade, integrated and automated laboratory, combined with a genetic circuit-controlled, growth-coupled continuous evolution system based on OrthoRep that can evolve proteins with diverse functionalities. #ChemSky #ChemBio

www.nature.com/articles/s44... link ($)

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📣 Peptide Therapeutics Forum 2026
🗓️ 4-5. June, 2026 - Biozentrum University of Basel
Register and submit your abstract for a contributed talk until March 29 ➡️ ptf26.scg.ch
#ptf26 #scs #peptides #chemistry #medchem #chembio #switzerland #symposia

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📢Know someone worthy of the @rscbmcs.bsky.social Hall of Fame?

Nominations are open for the 2026 inductee recognising a prominent chemist for outstanding, sustained contributions to areas of interest to the BMCS #chemsky #chembio #medchem

Find out how to nominate🔽
www.rscbmcs.org/awards/hallo...

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LED3 Lectures The LED3 hub, consisting of researchers from the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden (IBL), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institu...

If you are interested, make sure to come by! More information can be found here: www.universiteitleiden.nl/en/science/l...

#Antibiotics #DrugDiscovery #LPS #Bacteria #Zosurabalpin #Chemistry #ChemBio

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We are looking forward to the LED3 Lecture by Thomas Clairfeuille from Roche on March 26th. He will talk about "The discovery and mechanism of lipid transport inhibition by the antibiotic Zosurabalpin"

www.universiteitleiden.nl/en/science/l...

#ChemBio #ChemSky #Antibiotics #DrugDiscovery

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PhD candidate Tolulope Oyewumi standing with advisor Mary Kay Pflum in Schaap Hall

PhD candidate Tolulope Oyewumi standing with advisor Mary Kay Pflum in Schaap Hall

Tolulope Oyewumi, of the Pflum Lab, delivered an insightful 4th year talk on: “Developing ATP analogs to study multispecific kinases.” Fantastic research, Tolulope! #wsuchemistry #chembio #NextStopPhD #ChemSky

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I am very excited and proud that Julia Pols very successfully completed their PhD in our group. They wrote an excellent PhD thesis and engaged in exciting in-depth discussions with all the opponents during the PhD defense. (1/5)
#PhDone #PhD #ProudPI #Antibiotics #ChemBio #ChemSky

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I am very happy that @mprothiwa.bsky.social joined us today for a department visit and a lecture. She gave a very interesting lecture on "Chemical strategies to understand bacterial immune evasion".
link.springer.com/protocol/10....
#ChemBio #ChemSky #Bacteria #Proteases #Probes

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Postdoctoral Research Associate in Chemical Biology Full time, 2 years fixed term Located at the School of Chemistry on the Camperdown Campus Opportunity to contribute to multidisciplinary research on new mitochondrial targeting agents Base Salary, Lev...

Chemical biology PhDs/postdocs: don't miss out! Liz New is hiring a 2-year postdoc position on making & using fluorophores, in Sydney, Australia. A great group in a great city.

#chembio #postdoc hunters - check out the @lizjnew.bsky.social lab for more.

usyd.wd105.myworkdayjobs.com/en-US/USYD_E...

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"Chemical strategies to understand bacterial immune evasion"

I am very happy that @mprothiwa.bsky.social will visit us on March 3rd to give a lecture on this topic at 15:00 in the Gorlaeus building, room CM3.23. If you are interested, make sure to come by.

#Bacteria #ChemBio #ChemSky #ImmuneSystem

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Amazing @led3hub.bsky.social Lecture by @thewoolab.bsky.social! She talked about her group's exciting work on protein C-terminal cyclic imids as natural ligands of cereblon for protein degradation. (1/3)
www.nature.com/articles/s41...

#TPD #DrugDiscovery #ChemBio #ChemSky #Degron

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We are very happy that Christina Woo (@thewoolab.bsky.social) visited us for a very well-attended LED3 Lecture. She talked about the importance of C-terminal cyclic imides as natural #degrons for protein degradation with important implications for targeted protein degradation.
#TPD #ChemBio #ChemSky

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#ABPP2027 will be happening in Leiden on June 2nd to 4th, 2027.

I am excited to be part of the organization together with an amazing team.

Sign up for our mailing list here: www.universiteitleiden.nl/en/science/l...

#ABPP #ChemoProteomics #ChemPro #ProteoProbes #ChemSky #ChemBio #DrugDiscovery

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#ABPP #ChemoProteomics #ChemPro #ProteoProbes #ChemSky #ChemBio #DrugDiscovery

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🎉Our February issue is live!

This month we cover ring-shaped electrochemical ion pumping, crosslinked lipid nanoparticles, a dialysate-free wearable artificial kidney, and more! #ChemSky #ChemBio #Physics

Read the issue here: www.nature.com/natchemeng/v...

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PhD candidate Rachael Tiamiyu standing next to her advisor Mary Kay Plum in front of Schaap Lecture Hall

PhD candidate Rachael Tiamiyu standing next to her advisor Mary Kay Plum in front of Schaap Lecture Hall

Congrats to Rachael Tiamiyu, of the Pflum Lab, on her 4th year talk: "Investigating Protein Methylation in Colorectal Cancer and Protein Acetylation in Cellular Processes.” #wsuchemistry #chembio #NextStopPhD #ChemSky

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The 2025 PhD prize of the Chemical Biology Division of the Société Chimique de France (SCF-ChemBio) has been awarded to Laurane Michel, who completed her PhD at @icsnlab.bsky.social under the supervision of @achevalierchembio.bsky.social

Congratulations !!

#ChemBio

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The 2026 SCF-ChemBio Young Researcher Award has been awarded to Dr. Sarah Hostachy, a researcher at the SyMMES laboratory, CEA Grenoble.

On behalf of the board of the Chemical Biology Division of the French Chemical Society (SCF-Chembio), we warmly congratulate her!

#ChemBio

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#DrugDiscovery #Automation #VirtualScreening #MedicinalChemistry #HitDiscovery #ChemSky #ChemBio

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Catching up with the Pflum Lab: "Thermal shift engagement assay for Class IIA histone deacetylase inhibitor screening" in the journal Results in Chemistry. #wsuchemistry #chembio #HDAC #ChemSky

All Authors: Lauren N. Kotsull, and Mary Kay H. Pflum

doi.org/10.1016/j.re...

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Synthesis, Structure, and Function of Heparan Sulfate Glycopolymers to Investigate Glycosaminoglycan–Protein Interactions ConspectusHeparan sulfate (HS), a highly sulfated glycosaminoglycan, varies in its disaccharide units, chain length, and sulfation patterns. HS structural diversity and its localization at cell surfac...

Publication Alert 🚨

The Nguyen’s paper focuses on rational design of glycopolymers and how precise molecular architecture governs interactions with heparan sulfate binding proteins (HSBPs), ultimately driving meaningful biological activity. #wsuchemistry #ChemBio #ChemSky

doi.org/10.1021/acs....

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