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Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...

www.science.org/doi/10.1126/...

Cover: 3D WT bulb, wedge-out view; VIPS alternates light-sheet imaging & photochemical sectioning. #ExM #LLSM #imaging #neuroscience

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