Latest posts tagged with #MouseModels on Bluesky
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🚨 Editor’s Choice 🚨
"Best practices in mouse models of skin transplantation," by Borges et al
www.amjtransplant.org/article/S160...
#SkinTransplantation #TransplantResearch #MouseModels
🧠 #Neuroskyence researchers using #MouseModels:
Build precision and confidence in stereotaxic surgery through this @jacksonlab.bsky.social workshop, where you'll develop practical skills to improve research quality and animal outcomes.
📅 April 8 – 10, 2026 | 📍 Bar Harbor, Maine
🔬 Maintaining high standards in surgical technique is essential for animal welfare and scientific rigor.
Researchers and veterinary professionals working with #MouseModels can build technical expertise across a range of procedures at this upcoming JAX workshop: www.jax.org/education-an...
Excited to share our group’s latest review article in the European Journal of Immunology, co-authored with Francesca Ronchi! 🎉
Gut Microbiota 🦠 shapes Ommunity, may fuel CNS Inflammation 🧠 (Mouse 🐁 +Clinical 🩺).
#CNSautoimmunediseases, #ImmuneSystem, #Microbiota, #Mousemodels, #Multiplesclerosis
Metascape enrichment analyses of marginally dysregulated genes in placentas of four mouse models of Down syndrome. (A) Heatmaps illustrating higher order aggregation of the enriched pathways for each model. All pathways within the top 20 clusters for each model were manually re-categorized into nine biological groups (shown at top). (B) Venn diagram showing overlap of enriched pathways in the 20 most significant functional clusters for each model. Fifteen pathways are shared among the four models, and ten additional pathways are shared among Ts65Dn, Dp16, and Ts66Yah.
Taisuke Sato, Diana Bianchi and colleagues show alterations in RNA expression, protein expression and redox homeostasis in the placentas of four mouse models of Down syndrome 🐭 . doi.org/10.1242/bio....
#Trisomy21 #DownSyndrome #MouseModels #Transcriptomics
We're so glad to highlight 2024 San Antonio NSC Pilot Awardee Dr. Valentina R. Garbarino in this NSC Pilot Awardee Spotlight. You can read about Dr. Garbarino's pilot project in the full interview here: bit.ly/4szuo5E #BiologyofAging #MouseModels
I am excited to share that our latest work is now available as a preprint on BioRxiv.
In this study, we describe and characterize a Pglyrp1-Cre mouse model and uncover previously unappreciated heterogeneity among Pglyrp1-expressing cells across mucosal lymphoid tissues.
#MucosalImmunity #MouseModels
A key debate: can mouse models truly predict human Alzheimer's treatments? Many question the translatability, noting that induced Alzheimer's in mice differs significantly from the complex, naturally occurring human disease. #MouseModels 2/7
The mouse study's tumor elimination results are "impressive," but experts urge caution. Mouse models often don't translate directly to humans due to physiological differences & small sample sizes. A key hurdle for any breakthrough. #MouseModels 2/6
Our “Genetics for laboratory animal research” course teaches the key principles required to be able to support work with genetically altered animals in research with a focus on #MouseModels
Enrol as part of a Level 4 Diploma or as individual #CPD
clast.org.uk/diplomas/lev...
8/12 Liu's prevention-focused vaccine showed remarkable mouse model results.
Mice with humanized skin were infected with acne bacteria after vaccination.
Vaccinated mice remained acne-free while control group developed lesions.
Antibodies neutralized the harmful enzyme.
#Vaccine #MouseModels
🔬 #Biomedical researchers and trainees: What surgical skill was toughest to master, and how did you overcome it?
Share your tips or hurdles — we want to learn from your experience!
#LabSkills #InVivoResearch #MouseModels
The Yale MMPC Animal Physiology Core offers advanced phenotyping for mouse models of diabetes, obesity, & metabolism.
Supporting research with precision tools to uncover mechanisms of metabolic disease.
🔬 Learn more: medicine.yale.edu/internal-med...
#Metabolism #MouseModels
Ordering metabolic tests for mice?
MMPC = your best resource: mmpc.org/shared/order...
#MMPC #MouseModels
New to #MouseModels in #BiomedicalResearch?
🐁 Learn about common strains & get resources to find the right mouse for your experimental plan with @jacksonlab.bsky.social: education.learning.jax.org/common-labor...
Topics:
🔹 Nomenclature
🔹 Breeding schemes
🔹 Strategies to reduce genetic drift
Cancer’s Protein Tug-of-War Ends with Gelatin Nanoparticle Knockout Surprise
#ScienceGoneGelatinous #DoubleTroubleProteins #NanoparticleNonsense #MouseModels #LungCancerRedux By: TheJestPress.com **Study Reveals Lung Cancer Cells Play Molecular Seesaw, New Gelatin Treatment Tips the Board—Mice…
Next week at the Training School, Silvia Mandillo will lecture on assessing motor function in mouse models—covering standard tests, home-cage monitoring, case studies, and the impact of sex and welfare on results.
#MouseModels #BehavioralNeuroscience @costprogramme.bsky.social #homecage
🚨New IMPC study!
👁️This latest study identified 14 genes linked to late-adult corneal dysmorphologies (LACD) using knockout mice from the IMPC,12 are novel to corneal biology,7 expressed in human cornea.
Read more here: iovs.arvojournals.org/article.aspx...
#Cornea #Aging #Ophthalmology #MouseModels
Our “Genetics for laboratory animal research” course teaches the key principles required to be able to support work with genetically altered animals in research with a focus on #MouseModels
Enrol as part of a Level 4 Diploma or as individual #CPD
clast.org.uk/diplomas/lev...
Need phenotyping for mutant mouse models? 🧬 Access models from MMRRC or KOMP and submit them to UC Davis MMPC for expert analysis!
Visit mmpc.org to order your test today. 🔗
#MouseModels #metabolicresearch
Very full schedule at our #IMGCglasgow workshop last week, delivered by MitoCluster team @robpitceathly.bsky.social, Carlo Viscomi, @mitogene.bsky.social, and @jim-ca.bsky.social. A pleasure to attend, thanks for the invite @mrcmousenetwork.bsky.social & IMGS! 🧬
#mitochondria #MouseModels #ECR
Our “Genetics for laboratory animal research” course teaches the key principles required to be able to support work with genetically altered animals in research with a focus on #MouseModels
Enrol as part of a Level 4 Diploma or as individual #CPD
clast.org.uk/diplomas/lev...
Our Director, Owen Sansom, and @mrcharwell.bsky.social Director, Sara Wells, have been reaching out to US colleagues at the @jacksonlab.bsky.social to strengthen international #collaboration and #DataSharing in #PreClinical research using #MouseModels
The genetic cause for hearing loss due to otitis media with effusion was investigated in a recent panel of #DownSyndrome (DS) #MouseModels. Find the DS mouse models used in the study in the National Mouse Archive
#MouseMuse #WorldDownSyndromeDay
archive.har.mrc.ac.uk/stock?id=6435
Our “Genetics for laboratory animal research” course teaches the key principles required to be able to support work with genetically altered animals in research with a focus on #MouseModels
Enrol as part of a Level 4 Diploma or as individual #CPD
clast.org.uk/diplomas/lev...
🚀 IMPC has now been cited in 8,000+ peer-reviewed publications!
🧬 With data and products for 9,000+ genes available to the scientific community, we’re driving discoveries in genetics and disease research.
Read more here: bit.ly/8Kpublications
#Genomics #MouseModels #OpenScience #Publications
The study utilized Lkb1-deficient KRASG12C and KrasG12D lung cancer mouse models. These models were treated with KRAS inhibitors to observe the effects of AST on drug resistance. The use of these models allowed for in vivo examination of tumor behavior and response to treatment. #mousemodels
Our “Genetics for laboratory animal research” course teaches the key principles required to be able to support work with genetically altered animals in research with a focus on #MouseModels
Enrol as part of a Level 4 Diploma or as individual #CPD
clast.org.uk/diplomas/lev...
Collaborative paper with MitoCluster's Jim Stewart 📰
@mrcmousenetwork.bsky.social @mrcharwell.bsky.social #mitochondria #mousemodels
The genetic cause for hearing loss due to otitis media with effusion was investigated in a recent panel of #DownSyndrome (DS) #MouseModels. Find the DS mouse models used in the study in the National Mouse Archive
#MouseMuse
archive.har.mrc.ac.uk/stock?id=6435
