#Mutations

Doppeldata - Adelaide Bioinformatics

@doppeldata.au

1 hour ago

#Sinners has vampires, 16 #Oscar noms & a record-breaking campaign.

Real talk: #mutations in the FECH #gene cause extreme UV sensitivity & skin pain — and some researchers link porphyria to early #vampire mythology.

#Science is scarier than fiction. 🧬🧛🏻‍♀️

#Oscars2026 #Genetics #FunFact

Sherry w/ a whY

@justiceforall.bsky.social

1 day ago

#BirdFlu #H5N1 And again,
ANIMAL AGRICULTURE 🤝 BIG PHARMA

Dangerous #viruses & #mutations will continue to be a major threat until we stop needlessly exploiting animals. We kill 140,000 chickens every single minute - & that’s only 1/many bird species we exploit

If you care enough to act - go vegan

SNES-FSU Toulouse

@snes-fsu-toulouse.bsky.social

1 day ago

Rappel : le @snes-fsu-toulouse.bsky.social déploie dès cette semaine son dispositif d'aide pour les #mutations Intra :
- visios mardi 17 et mercredi 18 ;
- rendez-vous téléphonique ;
- documentation.

A retrouver sur www.toulouse.snes.edu/spip.php?pag...

Ricardo Wang

@ricardowang.mastodon.social.ap.brid.gy

3 days ago

A very organic appearing digital double exposure of weeping willow tree in Portland Oregon and a long corridor full of metal doorways in a storage unit in Hillsboro Oregon. The end result looks like a corridor on a lost forgotten spaceship that has been overgrown with mutant or alien vegetation.

#digitalphotography #photomanipulation #doubleexposure #weepingwillow #StorageUnit #corridor #hillsboro #portland #surreal #sciencefiction #mutations #lostgeneration #generationship #nogenerativeai

Mutant Corridor on a Lost Generation Ship

SNUEP-FSU VERSAILLES

@snuepversailles.bsky.social

3 days ago

Vous êtes PLP muté(e) dans l'académie de Versailles. N'hésitez pas à nous contacter par mail à l'adresse snuepversailles@gmail.com pour préparer votre mutation intra
#mutations #inter #intra

CFDT Éducation Normandie

@cfdt-educnormandie.bsky.social

4 days ago

Mutation intra second degré : la CFDT vous accompagne - Fédération CFDT Éducation Formation Recherche Publiques Affecté dans une nouvelle académie à la rentrée 2026 ? Comment être aidé par les militants CFDT pour votre mutation intra second degré ?

Vous venez d'apprendre votre nouvelle académie d'affectation pour la rentrée 2026 : les militants et militantes de la @cfdt-efrp.bsky.social peuvent vous aider pour votre mutation intra dans cette académie. #mutations #CFDT #syndicalisme

SNES-FSU Toulouse

@snes-fsu-toulouse.bsky.social

5 days ago

Le mercredi #18mars, de 17h30 à 18h30, le @snes-fsu-toulouse.bsky.social organise une visio pour toutes et tous consacrée au mouvement de #mutations #INTRA.

Pour s'inscrire :
➡️ www.toulouse.snes.edu/spip.php?pag...

Melvin Sanicas, MD MSc MBA

@vaccinologist.bsky.social

5 days ago

Mutant #p53 doesn't just lose #tumor suppression: it actively drives replication stress and tumor growth. Targeting that vulnerability with Chk1 + ATM inhibitors could open the door to therapies for #cancers where p53 #mutations are extremely common like #lungcancer www.linkedin.com/posts/drmelv...

Giuseppe Michieli

@gmik69bsky.bsky.social

6 days ago

#H5N1 2.3.4.4b HA E190D and Q226H #mutations, picked up as minority #variants in a #patient, result in an inability to bind #sialic acid.

#H5N1 2.3.4.4b HA E190D and Q226H #mutations, picked up as minority #variants in a #patient, result in an inability to bind #sialic acid, etidiohnew.blogspot.com/2026/03/h5n1...

CGT Éduc'action 03

@cgt-educaction-03.bsky.social

1 week ago

Calendrier des #mutations intra, consultez nous pour établir et prioriser vos vœux. vous renseigner sur vos droits et les postes au mouvement.
Contactez vos élus CAPA via: eluscgteducauvergne@gmail.com
#followers
@cgteduc.fr

Microbes.Info

@microbesinfo.bsky.social

1 week ago

HIV can develop resistance to blockbuster antiviral lenacapavir—but at a cost to the virus Long-acting antiviral medications are transforming HIV prevention and care, requiring only minimalistic dosing. But as the use of lenacapavir expands, scientists are probing a critical question: If…

#HIV can develop resistance to blockbuster #antiviral #lenacapavir ...

| #virus | #AIDS | #Mutations | #fullerene | Via @sciencex.bsky.social

Scott Wahlstrom

@scottwahlstrom.bsky.social

2 weeks ago

Every living thing on earth is a mistake. #Mutations
#Evolution
#NaturalSelection

OG (from Brains Matter) 🇦🇺

@brainsmatter.bsky.social

2 weeks ago

What is a ‘cancer gene’? How genetic mutations lead to cancer Your body has trillions of cells. But a gene mutation in just one of them could prove fatal.

What is a ‘cancer #gene ’? How genetic #mutations lead to #cancer theconversation.com/what-is-a-cancer-gene-ho... #health #medicine #science #STEM #biology

🌿Bertins Botanicals🌱

@timbertin.bsky.social

2 weeks ago

Can't get enough of these leaves on some of my mutated monsteras 🤤🤩🤯

#monsteras #newleaves #houseplantcollection #planthoe #mutations

CyberTaters

@potato.software

2 weeks ago

Mutate Your Reality: Caves of Qud Has Landed on Nintendo Switch

techmash.co.uk/2026/02/25/m...

@techmashcouk #NintendoSwitch #CavesofQud #FreeholdGames #future #scifi #fantasy #mutations #potatonetics #robots #sentientplants #survive #games #gaming #gamers #gameplay #videogames

N5Dave

@n5dave.bsky.social

2 weeks ago

Mutate Your Reality: Caves of Qud Has Landed on Nintendo Switch

techmash.co.uk/2026/02/25/m...

@techmashcouk #NintendoSwitch #CavesofQud #FreeholdGames #future #scifi #fantasy #mutations #cybernetics #robots #sentientplants #survive #games #gaming #gamers #gameplay #videogames

💚 A Germy Doc 💚 🔞

@germycracker.bsky.social

3 weeks ago

Dumb Sketches Based off Mewgenics #Mewgenics #Fanart #Doodles #Mutations #CatGirl #Cute #Cyclops #TankClass #Tentacles #Meow #Art

Giuseppe Michieli

@gmik69bsky.bsky.social

3 weeks ago

Amino acid #mutations K54E and S154P in the #neuraminidase attenuate #H3N2 #canine #influenza virus in mice

Amino acid #mutations K54E and S154P in the #neuraminidase attenuate #H3N2 #canine #influenza virus in mice, etidiohnew.blogspot.com/2026/02/amin...

@markachu.bsky.social

3 weeks ago

#duet with @Coltmaier What'd you say?! #tmnt #mutation #roulette #teenagemutantninjaturtles TikTok video by Mark Bellofatto

#TikTok #tmnt #Raphael #Michaelangelo #teenagemutantninjaturtles #mutations #hey
www.tiktok.com/t/ZThXgKMCs/

Dustcircle

@dustcircle.bsky.social

1 month ago

DNA Mutations Discovered in The Children of Chernobyl Workers The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the children of those originally exposed, researchers have found – the first time such...

#DNA #Mutations Discovered in The Children of #Chernobyl Workers

www.sciencealert.com/dna-mutation...

Giuseppe Michieli

@gmik69bsky.bsky.social

1 month ago

Impaired #host shutoff is a fitness cost associated with #baloxavir marboxil #resistance #mutations in #influenza A virus PA/PA-X nuclease domain

Impaired #host shutoff is a fitness cost associated with #baloxavir marboxil #resistance #mutations in #influenza A virus PA/PA-X nuclease domain, etidiohnew.blogspot.com/2026/02/impa...

Rod2ik 🇪🇺 🇨🇵 🇪🇸 🇺🇦 🇨🇦 🇩🇰 🇬🇱 ☮🕊️

@rod2ik.bsky.social

1 month ago

Tchernobyl: les premiers intervenants sur le site ont légué leurs mutations à leurs enfants Près de quarante ans après l'explosion du réacteur, une étude révèle que l'exposition prolongée aux radiations a laissé une empreinte durable dans…

#Tchernobyl: les premiers intervenants sur le site ont légué leurs #mutations à leurs #enfants

#NO #NUCLEAR #WARS

www.slate.fr/sciences/tch...

🪬🧿VoidVVitch🔮✨

@thevoidvvitch.bsky.social

1 month ago

Just a reminder: #white skin, #blonde #hair, & #blue #eyes are scientifically proven to be #genetic #mutations.

Giuseppe Michieli

@gmik69bsky.bsky.social

1 month ago

The #impact of clade B #lineage 5 #MERS #coronaviruses #spike #mutations from 2015 to 2023 on virus entry and replication competence

The #impact of clade B #lineage 5 #MERS #coronaviruses #spike #mutations from 2015 to 2023 on virus entry and replication competence, etidiohnew.blogspot.com/2026/02/the-...

Tony Lee

@pigasuspress.bsky.social

1 month ago

Brad Peyton's #RAMPAGE was a fantastic #sci-fi #monster-movie about gigantic #mutations, a great addition to the #kaiju #subgenre.
#movies #filmsky

Anoop Arunagiri

@anooparunagiri.bsky.social

1 month ago

Unraveling C-Peptide’s Role in MIDY: A Structural Perspective Proinsulin folding requires dynamic positioning of the C-peptide to guide A- and B-chain alignment and disulfide pairing. Mutant INS-gene-induced diabetes of youth (MIDY) arises when single-residue substitutions disrupt this process. We mapped the conformational free-energy landscapes of wild-type (WT) proinsulin and seven MIDY variants using metadynamics and molecular dynamics simulations. WT exhibits a deep free-energy minimum at compact conformations. In contrast, MIDY mutants display a continuum of destabilization: E(A4)K retains near-WT stability, Akita (C(A7)Y), V(B18)A, and R(Cpep + 2)C show moderate loss of the native basin, while H(B5)D, L(A16)P, and Y(B26)C collapse the closed–open barrier and populate misfolded open states >50% of the time. Structural analyses reveal that WT and E(A4)K preserve robust A–C docking, with the C-peptide flexibly engaging the A-chain groove. Destabilizing mutants progressively erode these native A–C contacts while forming compensatory, non-native B–C interactions. Per-residue energy decomposition highlights the loss of canonical salt bridges and emergence of aberrant electrostatic and hydrophobic hot spots, correlating with the collapse of the folding free-energy barrier. Secondary-structure analysis further shows that mutants rigidify the normally disordered C-peptide, increasing helical or strand propensity in a mutation-specific manner. Collectively, these findings establish a continuum from near-native stability to overt misfolding, mechanistically linking single-site mutations to altered folding landscapes and aggregation risk in MIDY. The results highlight the C-peptide as a dynamic linchpin of proinsulin folding and suggest that restoring its flexible docking could provide a therapeutic avenue.

New from our group: Unraveling C-Peptide’s Role in MIDY: A Structural Perspective | ACS Omega pubs.acs.org/doi/10.1021/...

Congratulations @sranga88.bsky.social and my lab folks! 🎉

#proteinfolding #proinsulin #mutations #Cpeptide #structuralbiology #computationalbiology #MDsimulations

Giuseppe Michieli

@gmik69bsky.bsky.social

1 month ago

#PB1 #mutations as key #drivers of #influenza A virus #evolution

#PB1 #mutations as key #drivers of #influenza A virus #evolution, etidiohnew.blogspot.com/2026/01/pb1-...

Biochemistry and Cell Biology

@biochemcellbio.bsky.social

1 month ago

🧬🔥 Can we stack stabilizing #mutations to #engineer better #enzymes?
Using PROSS-guided design across structural states, researchers create #thermostable tannase variants with up to +6.5 °C Tm and 30% higher kcat
🚀 #protein design #bioengineering
https://ow.ly/bgkp50XW6Of

@techboltx.bsky.social

1 month ago

🌿⚡ Grow a Garden — Admin Abuse Times & Schedule EXPLAINED! 👇
👉 techboltx.com/grow-a-garde...

#GrowAGarden #AdminAbuseTimes #RobloxEvent
#RareSeeds #Mutations #GamingCommunity #TechBoltX

Giuseppe Michieli

@gmik69bsky.bsky.social

1 month ago

Intra-patient #neuraminidase #mutations in avian #H5N1 #influenza virus reduce #sialidase activity to complement weaker hemagglutinin binding and facilitate #human infection

Intra-patient #neuraminidase #mutations in avian #H5N1 #influenza virus reduce #sialidase activity to complement weaker hemagglutinin binding and facilitate #human infection, etidiohnew.blogspot.com/2026/01/intr...