Ziyad Al-Aly, MD • @zalaly Among people who had mild COVID-19, risk of death became insignificant 1 year after infection Risk of new post acute sequelae declined over time, but residual risk remained even at 3 years in the pulmonary, Gl and nervous systems. nature.com/articles/s4159... • Hospitalized COVID-19 Non-hospitalized COVID-19 Cumulative excess death per 1,000 persons 360 720 1,08 Days since SARS-CoV-2 infection 3 ir at risk -hospitalized COVID-19 114,864 96,770 86.8 pitalized COVID-19 20,297 13.574 11.2€ ice rate ratio (95% CI) •hospitalized COVID-19 1.58 (1.53 to 1.62) 0.97 (0.94 to 1.00)| 1.01 (0.97| pitalized COVID-19 3.17 (3.00 to 3.33) 1.44 (1.34 to 1.55) 1.29 (L.19: rate per 1,000 persons (95% CI) -hospitalized COVID-19 16.20 (14.90 to 17.51) -0.91 (-2.2 to 0.38) 0.22 (-1.14 sitalized COVID-19 58.85 (54.37 to 63.33) 14.16 (10.25 to 18.06) 8.16 (4.37: | PASC Neurologic Pulmonary Mental Gastrointestinal 22.3 Cardiovascular 19.0 Musculoskeletal 15.4 Cosgulation 16.0 Fatigue 142 Metabolic 4.72.8 Kidney 3.8 b PASC 0% 212.3 125.0 100 200 300 38.1 27.2 38.5 17.1 11.1 15.3 21.1 7.4 12.2 9.6 8.3 7.1 60 Number of sequelae Non-hospitalized COVID-19 56.1% 33.0% 25% 50% 75% Percentage contribution by year 41.2 14.2 10.9% 100%
#NotMild infections carry lasting risks.
