#ProteinImport

Trends in Biochemical Sciences

@cp-trendsbiochem.bsky.social

5 months ago

Online now - the Review "Interconnectivity of mitochondrial protein biogenesis and quality control" from @mitolab.bsky.social et al.

#ProteinImport #Proteaes #Proteolysis #Proteostasis

Read it here: authors.elsevier.com/sd/article/S...

Pure Science

@purescience.news

6 months ago

Caltech Researchers Upend Decades-Old Model of Mitochondrial Protein Import Researchers showed that many mitochondrial proteins enter the organelle during synthesis, guided by folding patterns and structural signals. This discovery revises decades of biochemical models. Mitochondria...

Caltech Researchers Upend Decades-Old Model of Mitochondrial Protein Import #Science #Biology #MolecularBiology #Mitochondria #ProteinImport #CaltechResearch

GetNews.me

@getnews-me.bsky.social

6 months ago

Caltech Study Reveals Cotranslational Import of Mitochondrial Proteins

Caltech found that ~20 % of mitochondrial proteins are imported cotranslationally as they emerge from ribosomes, challenging the classic post‑translational model. Read more: getnews.me/caltech-study-reveals-co... #mitochondria #proteinimport

Lakhan Ekal

@lakhanekal.bsky.social

6 months ago

Structure of Pex8 in complex with peroxisomal receptor Pex5 reveals its essential role in peroxisomal cargo translocation Peroxisomes are essential cellular organelles that enable the sequestered execution of a broad range of metabolic processes. Due to the lack of an internal protein synthesis machinery, they entirely d...

Our latest bioRxiv preprint on the molecular mechanisms underlying #Pex8's essential role in Peroxisomal Protein Import

A huge thanks to all authors and collaborators for their crucial support! 🙏

doi.org/10.1101/2025...

#Peroxisome #ProteinImport #CryoEM #XLMS #SAXS #Crystallography #AlphaFold3

Nature Cell Biology

@natcellbio.nature.com

1 year ago

Mitochondrial protein import stress - Nature Cell Biology Cells respond to mitochondrial protein import stress by regenerating clogged import sites and inducing stress responses. Mitochondria are thus tightly integrated into the cellular proteostasis and str...

☕️Interested in how cells respond to #mitochondria #ProteinImport stress? Read our Review article by Nikolaus Pfanner, Fabian den Brave & Thomas Becker.
👉🏽https://rdcu.be/ecb3x
bit.ly/3DgVkm5

Nature Cell Biology

@natcellbio.nature.com

1 year ago

👋Our February issue's out!
Cover: #glioblastoma

👉🏼Review on #mitochondria #ProteinImport
👉🏻Viewpoint on #LipidMetabolism
🔬 #HumanEmbryos #NuclearSpeckles #PhaseSeparation #autophagy #mitosis #pluripotency #hematopoiesis #LipidDroplets & more!
www.nature.com/ncb/volumes/...