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Posts tagged #RIPTAC

#TargetedProteinDegradation #InducedProximity #MolecularGlue #TPD #eTPD #PROTAC #LYTAC #MoDEA #KineTAC #PROTAB #AbTAC #EpiTAC #REULR #GlueTAC #TICTAC #AUTAC #ATTEC #AUTOTAC #TrogoTAC #RIPR #RIPTAC #AgnoTAC #FragTAC #SHEDTAC

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J&J swoops on cancer biotech Halda with $3bn takeover deal Johnson & Johnson has added to the flurry of M&A deals in pharma with an agreement to buy Halda Therapeutics and its RIPTAC anticancer platform.

#JohnsonandJohnson has added to the flurry of M&A deals in pharma with an #agreement to buy US biotech #HaldaTherapeutics and its #RIPTAC platform for generating small-molecule #cancer drugs.

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Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic Halda Therapeutics has started a clinical trial of its first-in-modality RIPTAC drug HLD-0915 in prostate cancer, to see if bifunctional drugs can provide tissue-specific activity.

Halda Therapeutics has launched its first RIPTAC, HLD-0915, into a Phase I trial for prostate cancer. This innovative bifunctional molecule induces tissue-specific target inhibition and showed promising preclinical results.
🔗 Read more www.nature.com/articles/d41...
#Oncology #ClinicalTrials #RIPTAC

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