Unlocking the hidden pocket on a billion dollar drug target | #DrugDiscovery #chemsky #TPD #CRBN
Latest posts tagged with #TPD on Bluesky
Unlocking the hidden pocket on a billion dollar drug target | #DrugDiscovery #chemsky #TPD #CRBN
Join us at the 6th TPD & Induced Proximity Summit Europe and Induced Proximity Summit in London, 10 to 12 March 2026, which brings together experts to explore the latest advancements in targeted protein degradation.
We look forward to seeing you there!
#PROTAC #TPD #DrugDiscovery
Amazing @led3hub.bsky.social Lecture by @thewoolab.bsky.social! She talked about her group's exciting work on protein C-terminal cyclic imids as natural ligands of cereblon for protein degradation. (1/3)
www.nature.com/articles/s41...
#TPD #DrugDiscovery #ChemBio #ChemSky #Degron
We are very happy that Christina Woo (@thewoolab.bsky.social) visited us for a very well-attended LED3 Lecture. She talked about the importance of C-terminal cyclic imides as natural #degrons for protein degradation with important implications for targeted protein degradation.
#TPD #ChemBio #ChemSky
#TPD #officer convicted in connection with #Walmart theft fired following internal investigation
A #Toledo #Policeofficer convicted in connection with Walmart #theft in 2025 has been fired following an internal investigation.
digg.com/toledo/922Ts...
www.youtube.com/watch?v=5Zbj...
⁉️How can policymakers support #education in #Sudan?
✅Develop long-term strategic plans
✅Coordinate with international, national & local initiatives
✅Recognize displaced communities as active partners
✅Invest in continuous #TPD
✅Adopt flexible policies for #EiE
➡️ inee.org/crisis-spotlight/sudan
Of course, here great gals and guys from Lund University do most of the "real" work, and my mates from Captor Therapeutics made and characterized this beautiful compounds to work as MGs. My input was to provide proteomic analysis, still I'm quite contet with this one ;)
Enjoy! #proteomics #TPD
2/2
#TargetedProteinDegradation #InducedProximity #MolecularGlue #TPD #eTPD #PROTAC #LYTAC #MoDEA #KineTAC #PROTAB #AbTAC #EpiTAC #REULR #GlueTAC #TICTAC #AUTAC #ATTEC #AUTOTAC #TrogoTAC #RIPR #RIPTAC #AgnoTAC #FragTAC #SHEDTAC
Back from the #INGM retreat with strong science, stimulating discussions, and inspiring talks. Glad to present our technologies to target and degrade protein clusters. To the next year… #TPD #biomolecularcondensates
#Thornton Town Hall Tonight (no public comment). Show up in person if you are able. Live stream here if you can't come in person: www.youtube.com/c/ThorntonCO...
#Flock #Palantir #LPR #TPD
Very much looking forward to the @led3hub.bsky.social Lecture by Christina Woo (@thewoolab.bsky.social)! I am sure it will be a great one.
If you are interested in #ChemicalProteomics and/or targeted protein degradation #TPD, you will not want to miss it.
#ChemSky #ChemBio #DrugDiscovery #degrader
We are looking forward to the LED3 Lecture of Christina Woo (@thewoolab.bsky.social) on February 26th. She will talk about "Rewriting Protein Modifications".
If you are interested, make sure to come by!
www.universiteitleiden.nl/en/science/l...
#ChemBio #ChemSky #ChemicalProteomics #TPD
A sweet little curly haired dog smiles for the camera.
A little curly furred dog wire a sign that said - Pet Dogs Read Books Fight Facism January 26, 2026
We didn't take signs. We had candles prepared but they weren't needed.
We arrived about 1615.
Found a nice group who were friendly & respectful. To include #TPD. Lotsa positive honking & a few sweet #dogs like Bugsy here. He & his Human have the right idea.
#PetDogs
#ReadBooks
#FightFascism
We were there a little late. It was a nice sized group, friendly, respectful. We didn't get any "bad" vibe from #TPD.
I have been so happy that #TPD has been with us, to protect and serve, as we have rallied and marched this past month.
At each protest that we've attended, #TPD has been with us to "protect and serve". And, I thank them for that. 💙
we hope you enjoyed this paper as much as we do! 😉😘
if you’re interested in working with an allosteric ligand, reach out to Prof. Woo 🫡 we’re more than happy to share 🙌🏼🩵✨ #thefutureisallostery #CRBN #TPD
It was very peaceful!
And #TPD was again making sure we were safe! Thanks, men and women in blue!
🔥#meTPD–Driven Cancer #Vaccine
#iVAC degrades #PDL1, drives tumor antigen presentation, and reprograms cells into APC-like messengers. Awakens bystander memory #Tcells, turning cold tumors hot—robust CD8⁺ activation & superior tumor control in humanized mice & organoids.
#TPD
Share to help!
Have you seen . . .
**Rickeyonn Talley** Temple, TX
www.missingkids.org/poster/NCMC/...
See something, say something . . .
24-Hour Hotline: 1-800-843-5678
Temple Police Department (TX) (254) 298-5500
#NCMEC #MissingKids #TPD #BobbyVForTheMissing
EU alert 🚨 The Commission will propose new rules on safer nicotine products in 2026, a year earlier than planned. Expect a push for flavour bans, pouch bans, online sales bans. This is the moment to pay attention. #TPD #HarmReduction clearingtheair.eu/post/analysi...
Overall, I hope that 2026 will yield at least the same degree of scientific progress as 2025. (12/12)
#Chemistry #ChemBio #Science #Antibiotics #Synthesis #TPD #Degrader #Proteomics #Kinases #RNA #Screening #CovalentInhibitors #DirectToBiology
Last paper post of the year!
Amazing @natchembio.nature.com paper by @thewoolab.bsky.social. PCMT1 installs cyclic imides at the C-terminus of proteins via SAM-dependent methyl ester formation, which then leads to degradation using cereblon.
www.nature.com/articles/s41...
#ChemSky #ChemBio #TPD
POV: You have iron defficiency 🥲 (Yes, unfortunately, I am the one falling xD) /w @j0hnn0o.bsky.social and @thepitdwellers.bsky.social
#twitch #clip #tpd #thepitdwellers #peak
Happy to share that my review "Clues for glues: from serendipity to nature's blueprints in degrader discovery" is now out: doi.org/10.1042/EBC2...
The field is moving fast, and there’s no shortage of open questions - what a great time to be thinking about where #molecularglues and #TPD go next!
Exciting @biorxivpreprint.bsky.social by the group of Gunda Georg. They developed a tissue-specific PROTAC that recruits the E3 ligase scaffolding protein MAGEA11 that is highly expressed in many cancers and otherwise only in sperm and placenta. www.biorxiv.org/cont...
#TPD #ChemSky #ChemBio
#Article in #MedComm
E3 Ubiquitin Ligases: Structures, Biological Functions, Diseases, and Therapy doi.org/10.1002/mco2...
#cancer #E3_UbiquitinLigase #AD #PD #PROTAC #TPD
Super funds accused of delaying insurance claims #insurance #tpd #totalandpermanentdisability
Does anybody else see #taylorswift ‘s FLORIDA! from #tpd as a nice companion piece to No Body No Crime from #evermore ? This makes all the sense to me.