#Tioneb - got me going #wat. My favorite #looper / #beatboxer. A legend. #sbx
Latest posts tagged with #SBX on Bluesky
#Tioneb - got me going #wat. My favorite #looper / #beatboxer. A legend. #sbx
YAAAAAAAAY!!! πππ welll done you two π¬π§ π π #WinterOlympics #SBX
OMG it's a GOLD medal!!! πππ #SBX #WinterOlympics
Love the banter between Ed and Tim, makes #snowboarding one of the most fun sports to watch. Just need Darren Fletcher and it's a Red Bull Soapbox Race reunion! #BBCSport #WinterOlympics #SBX
Just a reminder that THE most exciting event (IMHO) at the #WinterOlympics is tomorrow. First heats of the men's #SnowboardCross #SBX are at 12.45 π
Grace in the air, clutch on the groundβthis @beckettcollect authenticated #autographed photo of #LynnSwann captures the Hall of Famer who turned Super Bowl X into a ballet with 161 yards and MVP honors. eBay tinyurl.com/524z4sm3 Amazon tinyurl.com/2smfhdna
#SteelersLegend #SBX #authentic #beckett
sorry, aber das war jetzt dumm und dΓΌmmer...
#Finale #SBX #Snowboard
Rumours are that the data/results in the #biorxiv #preprint by #Roche #SBX team are old, or older, than current methods. I wonder how fast they can iterate to improve on read length? I think they want to concentrate on the #human #health #Dx market, e.g. #MRD, where short-reads are decent enough.
Sequencing by expansion (SBX) https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1.full.pdf
Sequencing by Expansion (SBX) β a novel, high-throughput single-molecule sequencing technology. #SBX #SequencingByExpansion #Nanopores #Sequencing #Genomics #Roche 𧬠π₯οΈ
www.biorxiv.org/content/10.1...
#SBX Fast WGS Clinical Benchmarking: Successfully detects small variants (SNV, Indel), large CNVs (duplications, deletions), and STR expansions in clinical samples, including Fragile X (856 CGG repeats in FMR1), Duchenne MD, and DiGeorge Syndrome. #AGBT25 #AGBT2025 #AGBT @AGBT @Roche
#SBX vs. @Illumina: Genome-Wide Coverage SBX provides higher coverage in high-GC regions, earlier drop-off in low-GC. With MAPQ>20, SBX covers 95.6% (1X) vs. 97.3% (Illumina). In GIAB high-confidence, SBX achieves 99.82% (1X), 99.45% (10X). #AGBT25 #AGBT2025 #AGBT @AGBT @Roche
π Sequencing by Expansion (SBX) β a novel, high-throughput single-molecule sequencing technology
π§βπ¬ Mark Kokoris, Matthew Corning, et al.
π @biorxivpreprint.bsky.social
π www.biorxiv.org/content/10.1...
#οΈβ£ #Sequencing #Genomics #NGS #SBX
Here is the #Roche #SBX sequencing by expansion (expandomer) manuscript to support all the #AGBTGM hype!
www.biorxiv.org/content/10.1...
Roche Plans 2026 Launch for SBX Nanopore Sequencing Platform. #Roche #SBX #Sequencing #Nanopore @genomeweb.bsky.social
www.genomeweb.com/sequencing/r...
π§¬π₯ π¦ π§«π§ͺπ¬
#Roche revealed their truly novel seq tech:
- #SBX Sequencing By eXpansion
- Stratos eXpandomers + Genia nanopores
- Customizable Q:len
- 200bp len but 150-1500 range
- Q29
- 15-30B reads throughput
- reusable
I'm about to forget #the454incident
omicsomics.blogspot.com/2025/02/roch...
Respect to @omicsomics.bsky.social on the super fast synthesis of #SBX impact.
And even if all it does is give Ion Torrent "a good hard shove towards oblivion", it's done its job π
#genomics 𧬠π₯οΈ
I'll be writing up my take on albertvilella.substack.com soon. What does it mean for Illumina, Ultima, Element and MGI Tech? Does it change the landscape for read length agnostic Oxford @nanoporetech.com? Will it commoditize counting applications π? #NGS #Roche #SBX #NovaseqKiller #ShortReads
Look forward to the @coregenomics.bsky.social take on #SBX π
Pretty lit Roche π§¬π§¬β±οΈ #SBX #Genomics
The multiomic / diagnostic crossover potential could be amazing π€©
Will the world of short-read Next-Generation Sequencing change forever? We are about to find out! #Roche #SBX #ShortReads #NovaSeqKiller
Ooh #SBX has a lot of hits and some of them are about read length. π§ͺ π§¬
If I forget the π§ͺ 𧬠does my post dangle out there in purgatory? #Xpandomer is not a banana to fruit flies ... yet. Maybe in 3 days. Or next Monday the bananas breakfast sponsored by Roche. Or the 25th Roche #SBX workshop.
When I was on the #ABRF Executive Board my one push was to have an ABRF Europe meeting on Santorini. They have a great set up for 300+. Cheap flights etc we had to do it but ABRF was too stodgy back then to even think it was possible. Super cheap rooms right now. :-)
I would buy an #SBX unseen.
There is a big selfish side of me that wants the #Roche #SBX sequencer to work because I still remember the 454 European user meeting in Athens in 2010. That was swank! I gladly went back to the lab and did that awful protocol of loading the 454 afterwards. #lengthmatters