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#Splicing
Latest posts tagged with #Splicing on Bluesky
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Posts tagged #Splicing
🐟 Studying #zebrafish pituitary development, researchers show that ASO-induced suppression of gene #splicing leads to the dysregulation of intronic primary #microRNAs.
www.nature.com/articles/s42...
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We have an open position for a #PhD student (last week to apply!) & a lab technician/TA. For more information see: www.beuschlab.org/join-us
Interested in understanding post-transcriptional regulation and how #RNA #splicing decisions are made? Then take a look or share with people who might be! 🧪🧫
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🎨 Reposting these with Alt Text for each character~
#sprites #splicing #ocs #gymleaders #elitefour #professor #pokemon
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Do you want to understand how RNA #splicing decisions are made? We‘ve got a PhD position open for you (see 👇👇)!!
Please share #RNAsky and RT!
tinyurl.com/4ztu9cb9
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We’re excited to introduce scCHyMErA-Seq, a scalable #CRISPR-based #exon-deletion screening platform with #single-cell transcriptomic readouts, enabling high-throughput functional analysis of #alternative #splicing. In collaboration with the Gonatopoulos-Pournatzis lab. @natcomms.nature.com
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We analyzed 17 BRCA1 and BRCA2 variants associated with hereditary breast and ovarian cancer to evaluate their impact on RNA splicing. Eight variants showed aberrant splicing, while nine had no spliceogenic effect, enabling improved variant classification. 🔬 This work contributes to refining the clinical interpretation of BRCA1 and BRCA2 variants and highlights the importance of combining experimental and computational evidence for genetic risk assessment. https://academic.oup.com/clinchem/advance-article/doi/10.1093/clinchem/hvaf177/8416539. https://doi.org/10.1093/clinchem/hvaf177. Epub ahead of print. PMID: 41499258.
✨ We are starting the year with great news! 🎉 Our new paper titled "Splicing predictions, splicing assays and variant classification using ACMG/AMP guidelines: challenges observed with BRCA1 and BRCA2 variants" has been published. 🧬
#Genetics #BRCA #HereditaryCancer #Splicing #ACMG #Research
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🚨Postdoc opportunity🚨Our lab at MRC-LMB Cambridge is recruting a postdoc to study transcription-coupled splicing using cryoEM and endogenous isolation! 🔬 🧬
Please feel free to get in touch directly #postdoc #cryoEM #biochemistry #splicing
Apply here by 11 Feb
www.nature.com/naturecareer...
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📽 G&D Tapes 📽
G&D Author, Alexandra Bergfort, tells us about their new study in #genesdev showing how the EJC coordinates splicing of exon blocks
Learn more:
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
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RESEARCH PAPER: The exon junction complex coordinates the cotranscriptional inclusion of blocks of neighboring exons
By Bergfort et al., and Karla Neugebauer
➡️ https://genesdev.cshlp.org/content/40/1-2/94.full
Karla Neugebauer Alexandra Bergfort
Yale Center for RNA Science and Medicine
#splicing
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