🩺 Differentiation Syndrome
- complication that can occur during treatment of APL w/ ATRA+ATO
Clinical:
⬆️ WBCs
⬆️ Fever
⬆️ edema/body weight/pulmonary infiltrates
Mgmt:
- high-dose steroids
- cytoreduction
- antipyretics / cxs / abx for FN
- diuresis
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