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Tracking Cognitive Health With Wearables in Telerehabilitation Female Participants: Could Nighttime Sleep Measures Be Used as Sex-Specific Digital Endpoints? While changes in brain structure are common across the lifespan, it is difficult to differentiate benign variations from early disease pathogenesis, especially in patients participating in home-based rehabilitation. Cognitive decline is frequently linked with normative aging, but its early detection can facilitate preventative interventions, particularly in patients at high risk of cognitive impairment and dementia, such as older women. Although women have fewer modifiable risk factors for dementia than men, wearables have the potential to establish new digital endpoints that facilitate the management and/or prevention of abnormal brain aging. Sleep, which is necessary for maintaining overall brain health, is one behavior tracked via wearables, for which an ever-growing body of pilot and validation phase studies exists, yet endpoints defining optimal sleep are not one-size-fits-all, as individual chronotype variability necessitates new strategies to personalize care. Though sex-based differences in circadian rhythm are well established, little is understood about which sleep measures and thresholds are uniquely important to cognitive health in women, particularly those with high comorbid burden. In this viewpoint, we discuss recent findings on the use of wearables to track sleep and cognitive health in women, while highlighting challenges and opportunities for health outcomes and clinical trial researchers seeking to implement meaningful digital endpoints in future telerehabilitation programs.

Tracking Cognitive Health With Wearables in Telerehabilitation Female Participants: Could Nighttime Sleep Measures Be Used as Sex-Specific Digital Endpoints? #CognitiveHealth #Wearables #Telerehabilitation #DementiaAwareness #BrainAging

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Childhood trauma is linked to different aging patterns in the midlife brain A new study reveals a connection between early life trauma and adult brain aging. Adults reporting severe childhood stress demonstrated a stronger link between advancing age and declining mental skills, alongside distinct gray matter volume differences.

Childhood trauma is linked to different aging patterns in the midlife brain #Science #HealthandMedicine #MentalHealth #ChildhoodTrauma #BrainAging

www.psypost.org/childhood-trauma-is-link...

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New Cohort of the Week from @nataging.nature.com!
By analyzing nearly 1,000 human CSF samples, researchers mapped thousands of protein changes linked to #BrainAging and AD. #Proteomics on large human cohorts set the foundation for CNS markers of an aging brain.
pmc.ncbi.nlm.nih.gov/articles/PMC...

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Ageing promotes microglial accumulation of slow-degrading synaptic proteins - PubMed Neurodegenerative diseases affect 1 in 12 people globally and remain incurable. Central to their pathogenesis is a loss of neuronal protein maintenance and the accumulation of protein aggregates with ageing<sup>1,2</sup>. Here we engineered bioorthogonal tools<sup>3</sup> that enabled us to tag the …

This Nature study shows how aging slows protein cleanup in the brain, leading microglia to fill up with old synaptic proteins. Andrew Yang (BARI) contributed key methods to reveal it. Interesting for neurodegeneration research: pubmed.ncbi.nlm.nih.gov/41565824/ #neuroscience #brainaging

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A brain aging study is catching the attention of elite athletes, reframing longevity science as a competitive edge rather than a late-life concern.

longevity.technology/news/brain-a...

#longevity #brainaging #athleticperformance #humanoptimization #sportscience #healthspan

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It’s scary to feel like your mental sharpness is slipping away as you age. 🧠 Pineal Guardian protects your cognitive health, keeping your mind quick and your focus crystal clear for years to come. ✨🛡️ us-pinealgaurdian.com

#CognitiveLongevity #BrainAging #Neuroprotection #MentalSharpness #Brain

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Watching your memory and focus slip away as the years go by is so scary. 😔 Pineal Guardian supports your cognitive health to keep your mind sharp and youthful at any age. 🧠✨ us-pinealgaurdian.com

#CognitiveHealth #BrainAging #MemorySupport #Neuroprotection #MentalSharpness #BrainWellness

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Alzheimer’s research-shaping precision approaches to brain aging and dementia.

GLOBAL LONGEVITY FEDERATION 2026
📅 March 23–24, 2026
📍 Rome, Italy | Hybrid Event

🔗 longevityfederation.com

#GLF2026 #BrainAging #AlzheimersResearch #Neuroscience #LongevityScience #PrecisionMedicine #Biomarkers

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Mitochondrial DNA variation is reshaping how we understand brain aging from the cerebral cortex to the cerebellum.

11th Edition | GCAG 2026
📅April 20–21, 2026
📍Dubai, UAE

agingcongress.com/edition2

#BrainAging #MitochondrialDNA #Neuroscience #Neurodegeneration #CognitiveHealth

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Do all brain cells age the same way? 🧠

From senescence to astrocytes, this interview explores why brain aging is more about cellular function than time, and why different brain regions age differently.

🔗 Read the full interview: ow.ly/wray50XKQoK

#BrainAging #Neurochemistry #WeAreNeurochemistry

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Association between Klotho levels in cerebrospinal fluid and choroid plexus enlargement in neurodegeneration - PubMed In this preliminary study, we observed a strong association between CSF Klotho levels and CP enlargement. Reduced CSF Klotho levels, due to CP dysfunction, may contribute to neurodegeneration. If confirmed in larger cohorts, this association suggests that CSF Klotho may serve as a biomarker for CP e …

📢 New paper published! We show an association between CSF #Klotho levels and #choroidplexus enlargement in #neurodegenerativediseases, supporting CSF Klotho as a potential biomarker of choroid plexus dysfunction and #brainaging.

👉 Read the paper here: pubmed.ncbi.nlm.nih.gov/41393109/

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Research links age-related cortical microcircuit changes to EEG biomarkers, enabling non invasive detection of brain aging and cognitive decline.

11th Edition GCAG 2026
🗓 April 20–21, 2026
📍 Dubai, UAE

agingcongress.com/edition2

#BrainAging #Neuroscience #EEG #Biomarkers #Gerontology #GCAG2026

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I attended “Brain Aging - How time shapes the brain,” exploring how aging alters memory, attention, and connectivity, while plasticity and circuit reorganization support resilience👨‍🦳🧠.
#BrainAging

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🌟 Meet the AGE Board 🌟
Spotlight on Dr. Constanza Cortes (USC) — exploring how exercise and the muscle-brain axis can preserve brain health and combat age-related cognitive decline.

#AgingResearch #Geroscience #BrainAging #ExerciseScience #Longevity #AGEBoard #USC

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Do our brains only reach "adult mode" in our 30s? - Professor Ian Robertson speaks to @rteradio1.bsky.social @ianhrobertson.bsky.social

Listen to the 5 minute radio segment: tinyurl.com/2zb85ea8

#neuroscience #neurosciences #psychology #aging #adult #gettingold #brainaging #TrinityCollegeDublin

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Your Brain Has Five Ages — And They Shape How You Think for Life Learn how five distinct brain ages guide the way we think, learn, and grow older.

Your Brain Has Five Ages — And They Shape How You Think for Life #Science #HealthandMedicine #MentalHealth #BrainAging #Neuroscience

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Speaking Multiple Languages May Slow Brain Aging, Study Suggests A consistent pattern is emerging.

Speaking Multiple Languages May Slow Brain Aging, Study Suggests #Science #HealthandMedicine #MentalHealth #CognitiveHealth #Bilingualism #BrainAging

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Scientists Identify Five Distinct Eras of Human Brain Aging Human brains go through five distinct phases of life, each defined by its own set of characteristics, according to a new study

Scientists Identify Five Distinct Eras of Human Brain Aging #Science #Biology #Neurobiology #BrainAging #Neuroscience #MentalHealth

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🤔Why do some brains age faster than others?🧩The secret may lie in #Microglia gossip—tiny cells dictating who thrives or fades! @mdpiopenaccess.bsky.social
#Neuroinflammation #Microglia #BrainAging 🧠 Learn more 👇
doi.org/10.20944/pre...

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🤔Why do some brains age faster than others?🧩The secret may lie in #Microglia gossip—tiny cells dictating who thrives or fades! @mdpiopenaccess.bsky.social #Neuroinflammation #Microglia #BrainAging 🧠
Learn more 👇
doi.org/10.20944/pre...

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Reverse Brain Aging: Simple Habit for a Younger Mind Want a sharper mind? Discover the science-backed habit that can make your brain feel years younger. Read now!

LifeNextDaily News!
Feel like your brain is aging too fast? Discover the science-backed habit that could reverse the clock and make you feel younger! #BrainHealth #CognitiveFunction #BrainAging

Click here↓↓↓

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This #podcast episode was made possible with support from @innovativeresearch.bsky.social.

#science #research #STEM #anthropology #evolution #evolutionarybiology #molecularbiology #genetics #aging #brainaging #inflammaging #podcast #podcasts #scicomm #sciencecommunication @phdmarie.bsky.social

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Poor Sleep Linked to Faster Brain Aging, Study Shows

Poor Sleep Linked to Faster Brain Aging, Study Shows

A study finds that poor sleep is associated with faster brain aging. Read more: getnews.me/poor-sleep-linked-to-fas... #sleep #brainaging

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Bad Sleep Makes Your Brain Age Faster, Study Finds Poor sleep may age the brain faster, according to a major imaging study from Karolinska Institutet. People who struggle with poor sleep tend to have brains that look older than their actual age, according...

Bad Sleep Makes Your Brain Age Faster, Study Finds #Science #HealthandMedicine #MentalHealth #SleepHealth #BrainAging #MentalHealthResearch

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Poor sleep may make your brain age faster – new study | The-14 Poor sleep may accelerate brain ageing, with disrupted rest linked to inflammation and cognitive decline. Healthy sleep habits can help protect brain health.

Poor sleep may make your brain age faster – new study
#Health #Brain #SleepHealth #BrainHealth #Sleep #CognitiveDecline #HealthyHabits #Neuroscience #SleepScience #BrainAging #MentalHealth #Wellness #HealthResearch
the-14.com/poor-sleep-m...

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Job Alert

POSTDOC (M/F/X) NEUROSCIENCE AND BIOINFORMATICS

Deadline: 2025-11-09  
Location: Germany, Jena  

www.academiceurope.com/ads/postdoc-...

#hiring #Postdoc #Neuroscience #Bioinformatics #BrainAging #biology #computerscience

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Chronic insomnia linked to faster cognitive decline and brain aging A new study reports that individuals with chronic insomnia may face a more rapid decline in memory and thinking abilities as they age. Published in Neurology, the medical journal of the American Academy...

Chronic insomnia linked to faster cognitive decline and brain aging #Science #HealthandMedicine #MentalHealth #ChronicInsomnia #CognitiveDecline #BrainAging

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This Special Diet May Slow Brain Aging, Harvard Study Reveals The green-Mediterranean diet may protect against brain aging by reducing protein markers linked to cognitive decline. Adopting a green-Mediterranean diet, which incorporates green tea and the aquatic...

This Special Diet May Slow Brain Aging, Harvard Study Reveals #Science #HealthandMedicine #Nutrition #BrainAging #NutritionScience #HealthyDiet

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The COVID-19 Pandemic Is Associated With Accelerated Brain Aging Researchers utilized longitudinal neuroimaging data to examine the effect of the COVID-19 pandemic on brain age.

The #COVID19 pandemic is associated with accelerated #brainAging, even among individuals who were not infected with SARS-CoV-2. From @neurologyadvisor.bsky.social.

https://bit.ly/4m8YV63

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A new study suggests chronic insomnia may be an early warning sign or contributor to cognitive decline.

youtu.be/J0EzgnpJncc

#BrainAging #CognitiveDecline #SleepDisorders #NeurologyStudy #MemoryLoss #AlzheimersRisk #SleepAndBrainHealth #InsomniaAwareness #MentalDecline #HealthySleep

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