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How AI could help map the organized chaos in our cells As artificial intelligence seeps into some realms of society, it rushes into others. One area it's making a big difference is protein science — as in the

How AI could help map the organized chaos in our cells #Science #Biology #CellBiology #AIinBiology #CellMapping #TechInnovation

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Mapping cells through time and space with moscot | Nature Single-cell genomic technologies enable the multimodal profiling of millions of cells across temporal and spatial dimensions. However, experimental limitations hinder the comprehensive measurement of cells under native temporal dynamics and in their native spatial tissue niche. Optimal transport has emerged as a powerful tool to address these constraints and has facilitated the recovery of the original cellular context1–4. Yet, most optimal transport applications are unable to incorporate multimodal information or scale to single-cell atlases. Here we introduce multi-omics single-cell optimal transport (moscot), a scalable framework for optimal transport in single-cell genomics that supports multimodality across all applications. We demonstrate the capability of moscot to efficiently reconstruct developmental trajectories of 1.7 million cells from mouse embryos across 20 time points. To illustrate the capability of moscot in space, we enrich spatial transcriptomic datasets by mapping m

Discover how single-cell genomics combines temporal/spatial data using optimal transport. Boost your bioinformatics with moscot! #CellMapping PMID:39843746, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08453-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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Largest single-cell map of the aging brain reveals vulnerable cell types and regions A new study published in Nature offers the most detailed map to date of how individual cell types in the brain change with age. Scientists analyzed over 1.2 million brain cells from young and aged mice...

Largest single-cell map of the aging brain reveals vulnerable cell types and regions #Science #Biology #Neurobiology #AgingBrain #CellMapping

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Human Cell Atlas Maps Cells Across Organs for Disease Research Scientists unveil a high-resolution Human Cell Atlas, mapping cell functions and interactions to advance health and disease research | TGC News

Scientists unveil a high-resolution Human Cell Atlas, mapping cell functions and interactions to advance health and disease research | TGC News.

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