#cgrp

A Key Migraine Mechanism Is Responsible for Endometriosis Pain - Migraine Science Collaborative CGRP signaling from neurons to immune cells drives endometriosis pain and lesion growth, suggesting that CGRP-blocking drugs could be a potential treatment for the condition.

2 months ago

The countdown continues: The second most popular article on MSC this year covered a study showing that a key #migraine mechanism -- #CGRP signaling -- also plays a role in #pain resulting from endometriosis. Take a look on MSC today.
migrainecollaborative.org/a-key-migrai...

4 2 0 0

NeurologyLive®

@neurologylive.bsky.social

3 months ago

Real-World Meta-Analysis Confirms Efficacy and Safety of CGRP Treatment Galcanezumab in Migraine | NeurologyLive - Clinical Neurology News and Neurology Expert Insights Over the first 3 months of treatment, over 60% of patients with migraine treated with galcanezumab attained at least a 50% reduction in monthly migraine or headache days.

🆕 real-world #data 📊
Galcanezumab cuts monthly #migraine & #headache days by 50%+ in most patients — with generally mild side effects

Galcanezumab is the only #CGRP monoclonal antibody with high response rates in episodic migraine headache populations

🔗 ➡️ www.neurologylive.com/view/real-wo...

0 0 0 0

Régis Andrade

@regisandrade32.bsky.social

4 months ago

Pesquisadores australianos descobriram que proteínas do sistema nervoso, CGRP e RAMP1, estimulam o crescimento de tumores gastrointestinais.

Matéria completa - regisandrade.com.br/remedio-cont...

#pesquisadores #australianos #sistemanervoso #câncergastrointestinal #CGRP #RAMP1

0 0 0 0

BioNews Central

@bionewscentral.com

4 months ago

Key nervous system components shown to influence gastrointestinal tumor growth – BioNews Central New research reveals that common nervous system components influence tumor growth in the gastrointestinal tract, opening up previously untapped opportunities for cancer treatment. ...

New research reveals that common #NervousSystem components influence #TumorGrowth in the #GastrointestinalTract, opening up previously untapped opportunities for #CancerTreatment.
#CGRP #ColorectalCancer #StomachCancer #GastrointestinalCancers #TherapeuticTargets

0 0 0 0

European Journal of Neurology

@europeanjournalofneurology.ean.org

5 months ago

Argyriou et al. find that migraine worsens after discontinuation and early effectiveness is reduced upon re-initiation, challenging mandated CGRP pauses.

📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache #CGRP
@ean.org #WileyNeuro

1 0 0 0

5 months ago

Check out "PACAP versus #CGRP in #migraine: From mouse models to clinical translation." This article is an editor's pick in the latest installment of the MSC biweekly literature recap. Take a look at all the papers that made the grade this time around.
migrainecollaborative.org/paper-date/2...

1 1 0 0

@grantsrivers.bsky.social

7 months ago

Authors find some commercially available #CGRP ELISA detection kits don't accurately detect CGRP, highlighting importance of understanding research tools to ensure accurate results interpretation
headachejournal.onlinelibrary.wiley.com/share/FAUMUN...

1 1 0 0

Grant Rivers

7 months ago

Fingers crossed I get some benefit with these! 💉

#Migraine #Emgality #CGRP #Galcanezumab #ChronicMigraine #FND

2 0 2 0

A Key Migraine Mechanism Is Responsible for Endometriosis Pain - Migraine Science Collaborative CGRP signaling from neurons to immune cells drives endometriosis pain and lesion growth, suggesting that CGRP-blocking drugs could be a potential treatment for the condition.

7 months ago

One of our most popular articles so far this year covered a study showing that #CGRP signaling from neurons to immune cells drives endometriosis #pain and lesion growth, suggesting that CGRP-blocking drugs could be a potential treatment for the condition.

migrainecollaborative.org/a-key-migrai...

2 2 0 0

New Clinical Trial Results: Anti-CGRP Treatment Improves Migraine and Comorbid Depression - Migraine Science Collaborative The first study of its kind shows that fremanezumab could be an effective drug to manage this common comorbidity of migraine.

8 months ago

Check out our latest news story! The first study of its kind shows that fremanezumab could be an effective drug to manage both #migraine AND comorbid #depression. #headache #CGRP

migrainecollaborative.org/new-clinical...

1 0 0 1

Andy

@andyjobbins.bsky.social

8 months ago

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances Lynch et al., identified novel targets on the wake-promoting pathways that can effectively treat pain-induced sleep disturbances. The authors demonstrated that Calcitonin gene-related peptide-express....

New study in Advanced Science investigates finds that blocking CGRP-expressing neurons in the parabrachial nucleus can significantly reduce sleep loss caused by acute pain.

#Pain #Sleep #Neuroscience #CGRP

advanced.onlinelibrary.wiley.com/doi/10.1002/...

0 0 0 0

Anti-CGRP Treatment Improves Prodromal Symptoms of Migraine - Migraine Science Collaborative A new phase 3 clinical trial shows that ubrogepant, a CGRP receptor antagonist, alleviates photophobia, fatigue, neck pain, and other prodromal symptoms.

8 months ago

In case your missed it: A new phase 3 clinical trial shows that ubrogepant, a #CGRP receptor antagonist, alleviates photophobia, fatigue, neck pain, and other prodromal symptoms. #migraine #pain

migrainecollaborative.org/anti-cgrp-tr...

2 1 0 0

Springer Medicine

@springermedicine.com

9 months ago

Disrupting Migraine Dynamics: A Narrative Review of the Consequences of Modern Anti-CGRP Monoclonal Antibody Therapies Evidence from clinical trials and real-world studies shows that anti-CGRP monoclonal antibodies reduce headache and migraine frequency, severity duration and impact of remaining migraine attacks,…

Evidence from clinical trials and real-world studies shows that anti-CGRP monoclonal antibodies reduce #headache and #migraine frequency, severity duration, acute medication use, and more.

Find out more in this #EdsChoice review 👉 buff.ly/wej9rpn

#NeuroSky #CGRP

0 0 0 0

Anti-CGRP Treatment Improves Prodromal Symptoms of Migraine - Migraine Science Collaborative A new phase 3 clinical trial shows that ubrogepant, a CGRP receptor antagonist, alleviates photophobia, fatigue, neck pain, and other prodromal symptoms.

9 months ago

In case you missed it: A recent trial shows that treating early -- during the premonitory (prodrome) phase -- can ease the prodromal symptoms themselves. Read more in MSC news. #migraine #headache #CGRP
migrainecollaborative.org/anti-cgrp-tr...

1 1 0 0

Potential drug interaction between calcitonin gene‐related peptide antagonists and neonatal Fc receptor inhibitors You have to enable JavaScript in your browser's settings in order to use the eReader.

9 months ago

Open Access:
In this Perspective piece, authors Alex Harlan PharmD BCACP & Kevin Weber MD MHA describe a potential drug interaction between #CGRP mAbs for #migraine & neonatal Fc receptor (#FcRn) antagonists for #MyastheniaGravis
headachejournal.onlinelibrary.wiley.com/share/TA8DGP...

0 0 0 0

CreakyJoints®

@creakyjoints.bsky.social

9 months ago

New from UP-END Migraine 🎧
Dr. Nina Riggins joins Erik Stone to talk CGRP therapies, med-overuse headache & health equity.
Listen here: ghlf.org/upendmigrain...
#UpEndMigraine #TalkingHeadPain #MigraineCare #CGRP #HealthEquity

2 0 0 0

Darren

@dazzy04.bsky.social

9 months ago

Two Emgality self injection pens upright and side by side.

Here goes my next migraine treatment. Here’s hoping that Emgality @elilillyandcompany.bsky.social injections work better for me! 🤞 🤞 #migraine #emgality #cgrp

1 0 0 0

Ubrogepant relieves early migraine symptoms and may help prevent full-blown attacks A phase 3 trial found that ubrogepant, given during the premonitory phase of migraine, improved common warning symptoms such as fatigue, light and sound sensitivity, and neck pain. These benefits were...

9 months ago

Open Access:
Post-marketing safety analysis of #migraine prophylactic #CGRP mAbs suggest most reported adverse effects were nonserious & in line with existing literature, but ongoing surveillance is important
headachejournal.onlinelibrary.wiley.com/share/ZXXJWJ...
Victoria Nikitina PharmD et al

0 0 0 0

Rajan Singh

@rajansingh.bsky.social

9 months ago

🆕🔥#NeuroGastroMotil
#Sex-specific alterations in intestinal neuronal-epithelial interactions between #CGRP & #Goblet cells secondary to elevated enteric #AlphaSynuclein potentially contribute to GI dysfunction in #Parkinson's Disease‼️
👉
onlinelibrary.wiley.com/doi/10.1111/nm…
#ANMSociety #ESNM

5 0 0 0

News Medical

@newsmedical.bsky.social

9 months ago

Ubrogepant relieves early migraine symptoms and may help prevent full-blown attacks www.news-medical.net/news/2025051... #Migraine #Headache #CGRP #Ubrogepant #Neurology #ClinicalTrial #Pharma #BrainHealth #Medical

0 0 0 0

<em>Headache: The Journal of Head and Face Pain</em> | AHS Journal | Wiley Online Library Calcitonin gene-related peptide (CGRP) is a potent cerebral vasodilator and part of the trigeminal migraine cascade. Newer migraine therapies target CGRP signaling for both acute and preventative man...

10 months ago

Open Access:
A Kuczynski & W Kingston share 1st cases of #galcanezumab use in someone w #MELAS & #eptinezumab in an individual w #CADASIL, suggesting #CGRP driven processes driving #migraine even in those w genetically determined disease
headachejournal.onlinelibrary.wiley.com/doi/full/10....

1 0 0 0

European Headache Federation

@ehfofficial.bsky.social

10 months ago

🦠 Are CGRP-targeted therapies associated with an increased risk of infection? Updated data from a meta-analysis.

➡️ doi.org/10.1186/s101...

#CGRP #migraine

0 0 0 0

An Outlook on CGRP Therapies for Migraine: A Conversation with Antoinette Maassen van den Brink - Migraine Science Collaborative In this Migraine Science Collaborative interview, Antoinette Maassen van den Brink discusses the role of sex hormones in migraine, her ongoing work to understand possible side effects of CGRP therapie...

11 months ago

In case you missed it, see our recent interview with Antoinette Maassen van den Brink, who discusses the role of sex hormones in #migraine, her work to understand possible side effects of #CGRP therapies, and the challenge of access to these drugs.
migrainecollaborative.org/an-outlook-o...

1 1 0 0

Stiftung Kopfschmerz / Migräne

@kopfwehstiftung.bsky.social

11 months ago

Eine Studie zeigt, dass Menschen mit #Migräne mit einer #CGRP Antikörpertherapie wesentliche Verbesserungen bei der Häufigkeit, den Auswirkuneng und Beeinträchtigungen durch Migräne erfahren und zufrieden damit sind.
👉Was sind eure Erfahrungen mit CGRP-Antikörpern?
Quelle: doi.org/10.1111/head...

0 0 0 0

An Outlook on CGRP Therapies for Migraine: A Conversation with Antoinette Maassen van den Brink - Migraine Science Collaborative In this Migraine Science Collaborative interview, Antoinette Maassen van den Brink discusses the role of sex hormones in migraine, her ongoing work to understand possible side effects of CGRP therapie...

11 months ago

Check out our latest interview! Antoinette Maassen van den Brink discusses the role of sex hormones in #migraine, her ongoing work to understand possible side effects of #CGRP therapies, and the challenge of access to these drugs.

Take a look: migrainecollaborative.org/an-outlook-o...

1 1 0 0