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Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects Walsh et al. establish a human forebrain assembloid protocol that supports the derivation of bona fide PVALB+ cortical interneurons and employ it to model schizophrenia in disease-associated structura...

Using #hPSC lines with schizophrenia-linked mutations, the team identified variant-specific disruptions in brain cell development and network activity.

Funded in part by @bbrfoundation.bsky.social

Read more in @cp-neuron.bsky.social
www.cell.com/neuron/fullt...

#devbio #devneuro

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Rainbow shading of a confocal micrograph of a developing mouse neural tube. The protein actin is stained and colored in rainbow to indicate depth in the section.

Rainbow shading of a confocal micrograph of a developing mouse neural tube. The protein actin is stained and colored in rainbow to indicate depth in the section.

Happy #FluorescenceFriday! This is a maximum intensity projection of depth shaded actin (🌈) in a section from an E9.5 🐭 neural tube (NT). 🔬 by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪 Image shows the floor plate and lumen of the developing NT.

#SciArt #DevBio #DevNeuro

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Also thankful for fellowship support from @hhmi.org in my PhD and now from @jcchildsfund.bsky.social!

#Neurodevelopment #Psychedelics #ChoroidPlexus #CSF #DevNeuro #Pregnancy #LSD #Preprint

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2026 Neural Development (GRS) Seminar GRC The 2026 Gordon Research Seminar on Neural Development (GRS) will be held in Newport, Rhode Island. Apply today to reserve your spot.

For all the #DevNeuro postdocs & graduate students...Neural Development GRS will be held right before - Aug 1-2, 2026 and is co-chaired by @deepthavasu.bsky.social & Aleksandra Recupero - we will post about this as well! Check out the website www.grc.org/neural-devel...

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Dennis D.M. O’Leary (1954–2024) Dennis D.M. O’Leary, neuroscientist and professor emeritus at the Salk Institute of Biological Studies in La Jolla, California, passed unexpectedly in early September 2024. His work fundamentally chan...

Obit for my former postdoc mentor Dennis O’Leary (1954–2024) written by many lab alumni. "O’Leary’s work over two decades established a conceptual framework for cortical arealization...and topographic mapping in the visual system". We miss you Dennis! ❤️🧠⚾ #devneuro www.cell.com/neuron/fullt...

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Thanks to the Society of Developmental Biology and those who volunteer to keep it running and serve our community. Feeling grateful and hoping for peaceful, happy, and healthy times globally!! #DevelopmentalBiology #DevNeuro 10(10)

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Starting my own lab, I was fortunate to find incredible mentors in neuroscience—Matt Kayser, Josie Clowney, and Kathy Nagel—who helped me bridge Developmental Biology with Neuroscience and helped me understand behaviors shaped by development. #DevNeuro 6(n)

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This is a huge recognition from the community I love so much. Winning the Elizabeth D. Hay New Investigator Award is a big surprise and honor! This recognition belongs to my incredible mentors, colleagues, and the amazing people in my lab. 1(n)

#DevelopmentalBiology #DevNeuro

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#Neuroscience 🧠peeps! Need recommendations for a summer program/course for my new graduate student to introduce them to #DevNeuro - they are coming from a completely different research area and want some more background training.

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🆕 in @natprot.bsky.social! 🧠 @giorgiaquadrato.bsky.social's lab at @keckschoolusc.bsky.social has developed pluripotent, stem cell-derived human cerebellar #organoids that can replicate the cellular diversity of the fetal cerebellum.
#devbio #devneuro #neuroscience

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Digital mockup for lab gift exchange art is done! Different colors represent germinal zones/cortical plate, basal nuclei anlage, choroid plexus, and other brain parenchyma.

#devneuro followers—can you catch any mistakes before I start cutting out the pieces?

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Another #FluorescenceFriday, another #neocortex. This one was testing out antibodies on E13 mouse (Tbr2, Pax6, Ki67, DAPI). The Ki67 wasn't great, but it makes for good art!

#DevBio #DevNeuro #neuroscience #neuroskyence

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I've been waiting all week for my first #fluorescencefriday entry!

Here's an old favourite from my PhD of P17 fat-tailed dunnart (marsupial) neocortex.

GFP transfected in green, intermediate progenitors in red, and mitotic cells in cyan.

#devbio #evodevo #neuroscience #devneuro

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