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Latest posts tagged with #freephd on Bluesky

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Posts tagged #freephd

@graeme.fawcett.social

1 hour ago

(4) astrocyte-specific GLT-1 conditional knockdown as a control arm to show the behavioral rescue depends on transporter redistribution and not a parallel pathway.

#freephd #astrocytesareagirlsbestfriend #neurostuffandthings #neuroscience #accordingtohoyle

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@graeme.fawcett.social

2 weeks ago

it’s a falsifiable quantitative link between a queueing threshold and the Higgs sector.

#physics #freephd

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@graeme.fawcett.social

1 month ago

The Grammar Layer of Self‑Regulation: Astrocytic Dysfunction at the Neurovascular Interface Self-regulation disorders—substance addiction, compulsivity spectrum conditions, ADHD, and thought/mood disorders—share a common phenotype: the inability to constrain ongoing behaviour despite insight, consequences, or competing goals. We propose this reflects a shared mechanism: dysfunction of the astrocytic "grammar layer" at the neurovascular interface in prefrontal and striatal control circuits. Across ten conditions we find a recurring four-column pattern: behavioural constraint failure, astrocyte dysfunction, neurovascular impairment, and symptom improvement with astrocyte-restoring interventions. The mechanism presents in four forms: exogenous damage, endogenous dysfunction, gradient undersupply, and structural degradation. Two immediately testable predictions are offered: (1) stimulant response in ADHD correlates better with perfusion change than dopamine transporter occupancy; (2) ketamine response in depression correlates better with astrocytic/perfusion markers than glutamatergic markers.

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[just needs someone to run the regression]

https://zenodo.org/records/18603643

#adhd #neuroscience #freephd

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@graeme.fawcett.social

2 months ago

Serious offer

#mathematics #freephd #getyourphdshere #winkyface #orisit

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