Latest posts tagged with #gapjunctions on Bluesky
Coincidence detection supported by electrical synapses is shaped by the D-type K⁺ current. New study from Antonella Dapino and Sebastián Curti (Universidad de la República, Uruguay) rupress.org/jgp/article/...
#CellularPhysiology #IonChannels #GapJunctions
Direct follow-up post: This example shows how to simulate a network of 500 inhibitory #SNN neurons with #GapJunctions using #NESTsimulator, analyzing the effects on #synchrony and #oscillations:
🌍 www.fabriziomusacchio.com/blog/2025-09...
#CompNeuro #Neuroscience #PythonTutorial #Python
🧠 New blog post on #GapJunctions: How #ElectricalSynapses synchronize #neurons & shape #NetworkDynamics. Includes a #modeling overview + small #PythonTutorial using #NESTsimulator. Feel free to share!
🌍 fabriziomusacchio.com/blog/2025-08-15-gap_junctions/
#Neuroscience #CompNeuro #OpenSource
Available now - the Review "The ins and outs of #connexins and #pannexins beyond the cell surface" from Henrique Girao and colleagues.
#GapJunctions #IntercellularCommunication #SubcellularTrafficking #ExtracellularVesicle #Mitochondria
authors.elsevier.com/a/1l6BQ3S6Gf...
Thanks to Dr. Henrique Girao and team for a great sabbatical visit to the beautiful University of Coimbra #connexins #pannexins #gapjunctions
Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).
Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu
Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).
Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu
Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).
Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu
Mind the Gap? This study re-examines #gapjunctions in the Zona #glomerulosa of mouse #adrenal #cortex, reporting RNA and protein expression of #connexin 43 and 37. However, in adrenal slice cultures, only limited evidence for GJ function was obtained.
https://buff.ly/40FEt3V
#CellCommunication
#Intro #postdoc @urochester.bsky.social working on depth and motion #perception using #neuropixels #ephys in #nhp. Previously #gapjunctions with #patchclamp #optogenetics. 🧪🧠 Passionate about #figureskating ⛸️.
