Authors include Robert Naviaux, Carmen Scheibenbogen, and Bhupesh Prusty
Closing in on the causes of PEM 🎯
#MECFS #LongCovid #ImmuneDysfunction #Mitochondria #AutoImmunity
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#immunedysfunction
Latest posts tagged with #immunedysfunction on Bluesky
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Posts tagged #immunedysfunction
Integrated #Multiomics maps the systemic immune landscape of PitNETs, revealing how secretory activity drives peripheral #ImmuneDysfunction and establishing these tumors as endocrine drivers of #ImmuneRemodelling.
#OpenAccess: doi.org/10.1038/s413...
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A new study reveals molecular-level changes in #inflammation and #ImmuneResponse caused by #ChronicFatigueSyndrome, which could guide development of #TargetedTherapies.
#ImmuneDysfunction
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Honored to share our latest paper on T-Cell Exhaustion's role in Post-Acute Infection Syndromes, now features YouTube!
Watch here: www.youtube.com/watch?v=WSNV...
#Immunology #TCellExhaustion #LongCOVID #ImmuneDysfunction #MedicalResearch #HealthcareInnovation #Qeios
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A modifiable #GeneSignature linked to #ImmuneDysregulation and poor #ImmuneHealth predicts severe #infection outcomes. This signature is present in individuals with risk factors such as #smoking or high #BodyMassIndex before #pathogen exposure.
#Obesity #ImmuneDysfunction #ImmuneResponse
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NIH acknowledges #LongCOVID causes #ImmuneDysfunction and repurposed HIV antiviral medications are a possible course of treatment.
#LongCOVID is #AirborneAIDS so #WearN95
www.nih.gov/about-nih/wh...
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These sub-awards build on the more than 40 pathobiology research projects(link is external) awarded in 2022 that are yielding important results. For example, one study found that severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, making some people susceptible to other infections. Another study found that symptoms for some long COVID sufferers appear to be caused by persistent infection and may respond to antiviral medications.
NIH acknowledging reality. "Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, making some people susceptible to other infections." #ImmuneDysfunction
www.nih.gov/about-nih/wh...
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How viral persistence and immune dysfunction drive long COVID 🔬🦠💡 www.news-medical.net/news/2024092... #LongCOVID #ViralPersistence #ImmuneDysfunction #Microclots #COVID19R #ChronicIllness #PostCOVID #Therapeutics #MedicalResearch #Inflammation
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This is so interesting! This RCT for bipolar depression showed that low dose IL-2 stimulated T-regs to turn off inflammation, and patients showed significant improvement. #ImmuneDysfunction🤯 www.medrxiv.org/content/10.1101/2024.07....
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Another good thread (by @SalvMattera on Twitter) on the risks posed by repeat #Covid infections & the recent upward trend in the latest CDC Household Pulse data:
threadreaderapp.com/thread/17651...
#LongCovid #ImmuneDysfunction
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So while the acute infection may be one reason to not want to keep getting infected with SARS-CoV-2 over and over again, the idea that it can increasingly cause damage to the immune system should be a significant reason. Throughout the pandemic, scientific evidence has mounted that even mild COVID infections may be doing something to our immune systems, as well as our collective immunity. For example, what if SARS-CoV-2 infection causes the immune system to be able to respond to SARS-CoV-2 in such a way that we no longer experience severe COVID infections, but rather it causes a subtler, long-term immunological changes that leave us more vulnerable to other infections or even chronic disease? Src: https://libguides.mskcc.org/CovidImpacts/Immune#:~:text=So%20while%20the,even%20chronic%20disease%3F
The COVID-19 Immune Dysfunction page of the Memorial Sloan Kettering Cancer Center:
libguides.mskcc.org/CovidImpacts...
#Covid #CovidIsntOver #ImmuneDysfunction
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