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Posts tagged #naturecomms

Humans with function-disrupting variants in the myostatin gene (MSTN) have increased skeletal muscle mass and strength, and less adiposity - Nature Communications This multi-cohort study reports genetic variants in myostatin associated with increased muscle mass, strength, and reduced adiposity. These findings support long-term myostatin blockade for muscle pre...

New #NatureComms paper: Humans with function-disrupting variants in the myostatin gene (MSTN) have increased skeletal muscle mass and strength, and less adiposity. #Myoblue tinyurl.com/mhsksrte

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A biological material that becomes stronger when wet could replace plastics 🌊

The new study is led by #BISTCommunity centre @ibecbarcelona.eu & published in #NatureComms

#ICYMI 👇
bist.eu/a-biological...

#Biomaterials #SustainableMaterials

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Senescence can be p53/p21- AND p16-independent😮(Though they are induced as bystander markers)

p300 HAT inhibition in fibroblasts
❎DDR
✅G2/M arrest
✅SAHF

#NatureComms 2011
www.nature.com/articles/nco...

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#Autophagy ⏫by Physiologic Laminar Shear (1 dyn/cm2) Sensing in renal epithelial cells

Primary Cilia-activated AMPK-SIRT1 axis traps YAP/TAZ in cytoplasm

Autophagy suppressors Rubicon & Cptp as direct YAP/TAZ target genes

#Zebrafish🐟
#NatureComms 2023
www.nature.com/articles/s41...

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https://www.nature.com/articles/s41467-026-68474-5

New #NatureComms paper: Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging. #Myoblue tinyurl.com/trenznfp

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https://www.nature.com/articles/s41467-025-67584-w

New #NatureComms paper: CHAMP1 is an essential regulator for human myoblast fusion and muscle development. #Myoblue tinyurl.com/2wyu39fr

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Your roommate’s genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published this week in #NatureComms by researchers at the #BISTCommunity centre @crg.eu

Learn more 👉 bist.eu/can-your-gen...

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https://www.nature.com/articles/s41467-025-65506-4

New #NatureComms paper: Non-canonical roles of Keap1/Nrf2 in regulating quiescence and early activation in adult muscle stem cells. #Myoblue tinyurl.com/5x6r7ffv

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https://www.nature.com/articles/s41467-025-65141-z

New #NatureComms paper: TBC1D1 functions as a negative regulator of satellite cells for muscle regeneration. #Myoblue tinyurl.com/2wk5pkjt

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https://www.nature.com/articles/s41467-025-64999-3

Interesting work from @rudnicki-lab.bsky.social in #NatureComms : Intrinsic dysfunction in muscle stem cells lacking dystrophin begins during secondary myogenesis. #Myoblue tinyurl.com/4byakujj

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Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction - Nature Communications The role of peroxisomes in skeletal muscle remains largely unexplored. Here, the authors show that peroxisomal dysfunction and disrupted crosstalk with mitochondria drive age-related muscle decline, u...

New #NatureComms paper: Alterations in peroxisome-mitochondria interplay in skeletal muscle accelerate muscle dysfunction. #Myoblue tinyurl.com/4knhr7mh

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Conversion from coniferous to broadleaved trees can make European forests more climate-effective - Nature Communications This study investigates the effects of forestation on temperature in Europe using climate model experiments. The findings indicate that conversion from coniferous to broadleaved trees in currently for...

🌳 Our research in Nature Communications!
Converting coniferous to broad-leaved forests in Europe could cut summer hot extremes by up to 1 °C — boosting climate effectiveness.
Read more 👇
🔗https://www.nature.com/articles/s41467-025-64580-y
#ForestNavigator #ClimateScience #Forestry #NatureComms

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Computational and Theoretical Biology As we navigate the era of big data in biological research, advanced computational techniques, such as mathematical models and machine learning algorithms, are ...

Thrilled 👏 to 👏see 👏 @jsb-ucla.bsky.social and Pan Liu’s “mcRigor” paper featured in the Computational & Theoretical Biology Editors’ Highlights at Nature Communications! Well done, Jessica and Pan! 🎉

🔗 www.nature.com/collections/...

#SingleCell #ComputationalBiology #Biostats #NatureComms

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Targeted volume imaging reveals early vascular interactions of Lyme disease pathogen in skin - Nature Communications Authors utilise scanning electron microscopy to show that Borrelia burgdorferi initiates systemic vascular spread by targeting pericytes, while crossing of the lymphatic endothelium occurs via sequent...

If you ever wondered what happened next at a tick bite site in terms of Borrelia dissemination ....wonder no more. Wonderful collaborative work between my lab and my collaborators Marie Vancova,Laboratory of Electron Microscopy, #NatureComms

www.nature.com/articles/s41...

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Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration - Nature Communications The mechanisms resulting in muscle satellite cell dysfunction in diabetes are not well understood. Here, the authors show that AS160 functions in the nucleus to regulate satellite cell proliferation a...

New #NatureComms paper: Nuclear entry of AS160 as a transcriptional regulator of satellite cells for muscle regeneration. #Myoblue tinyurl.com/2c3ax2ma

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Muscle-specific gene editing therapy via mammalian fusogen-directed virus-like particles - Nature Communications Genetic muscle diseases are difficult to treat due to challenges in delivering gene editors to muscles throughout the body. Here, authors engineer muscle-specific virus-like particles that fuse with s...

New #NatureComms paper: Muscle-specific gene editing therapy via mammalian fusogen-directed virus-like particles. #Myoblue tinyurl.com/35wcweap

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LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan - Nature Communications LARGE1 glycosyltransferase synthesizes matriglycan (xylose-glucuronate)n on dystroglycan, and short matriglycan can cause neuromuscular disorders. Authors show that LARGE1 processively polymerizes matriglycan of defined length on prodystroglycan.

New #NatureComms paper from Kevin Campbell and colleagues: LARGE1 processively polymerizes length-controlled matriglycan on prodystroglycan. #Myoblue tinyurl.com/ypw5cxm9

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Stage-specific and cell-autonomous functions of Delta-like 1 in skeletal muscle stem cells and myogenesis - Nature Communications Peng et al. show that DLL1-expressing muscle myoblasts not only regulate NOTCH signaling in neighbor cells but also send a retrograde signal to themselves via the DLL1 intracellular domain.

New #NatureComms paper: Stage-specific and cell-autonomous functions of Delta-like 1 in skeletal muscle stem cells and myogenesis. #Myoblue tinyurl.com/3cb86ham

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MetaboAnalystR 4.0
A unified LC-MS workflow for global #Metabolomics
#OpenSource R

www.metaboanalyst.ca/docs/RTutori...

Jianguo Xia lab #NatureComms 2024
www.nature.com/articles/s41...

Metabolomics Workbench
National Metabolomics Data Repository
>4k studies

www.metabolomicsworkbench.org

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Comparing single-cell #SpatialTranscriptomics methods on FFPE human tumor #TissueMicroArray

CosMx 1k vs MERFISH 500 vs Xenium-UM/-MM 339
93 common genes

lung adenocarcinoma
pleural mesothelioma

Corr. Bulk RNAseq, GeoMx

#NatureComms 2025
www.nature.com/articles/s41...

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#SpatialTranscriptomics Visium #CerebralMalaria

🐭+P.berghei ANKA -/+Artesunate

SPATA spatial trajectory inference of EC-rich spots in infected🧠▶️
⏫EC antigen processing/presentation + leukocyte adhesion
⏬BBB
Partially corrected by Artesunate

#NatureComms 2025
www.nature.com/articles/s41...

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Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity - Nature Communications Scaffolding protein ankyrin-B, implicated in cardiometabolic syndrome, enables mitochondrial fission and flexibility of nutrient utilization under energetic stress in skeletal muscle to support energy...

New #NatureComms paper: Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity. #Myoblue tinyurl.com/5n647f8k

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Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells - Nature Communications This study shows that two distinct progenitor populations build embryonic muscle in birds—one forms primary fibers via Wnt signaling, the other gives rise to secondary fibers and satellite cells—and t...

New #NatureComms paper: Early lineage segregation of primary myotubes from secondary myotubes and adult muscle stem cells. #Myoblue tinyurl.com/2yvdt3j9

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SMCHD1 maintains heterochromatin, genome compartments and epigenome landscape in human myoblasts - Nature Communications The authors characterize SMCHD1 as a nuclear lamina-associated protein in human myoblasts where it serves as an anchor for heterochromatin. Loss of SMCHD1 leads to B-to-A compartment transitions and n...

New #NatureComms paper: SMCHD1 maintains heterochromatin, genome compartments and epigenome landscape in human myoblasts. #Myoblue tinyurl.com/bubedsza

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Original post on mastodon.nl

#DaniBeckman ( @whn) on X wrote:

Once we thought it would be nearly impossible to modulate #LongCovid in rodent models, but science is getting there. More evidence for direct #COVID neuroinvasion, viral persistence in the brain , and more explanations for cognitive and psychiatric alterations […]

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I’ve had a blast at my first @big-stem-network.bsky.social meeting at the RI. Learning from a host of amazing people who dedicate their life to sharing the joy of science and make it as accessible as possible. From games and demos, to science TV shows and animal displays. #sciencecomms #naturecomms

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Early-life exercise extends healthspan but not lifespan in mice - Nature Communications Exercise exerts health benefits, yet the long-term effects of early-life regular exercise on later-life health and lifespan remain poorly understood. Here, the authors show early-life exercise in mice...

Interesting new #NatureComms paper: Early-life exercise extends healthspan but not lifespan in mice. #Myoblue tinyurl.com/29v6j4x4

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Seasonal stabilization effects slowed the greening of the Northern Hemisphere over the last two decades - Nature Communications Rising CO₂ and warming enhance vegetation greening, but drought, heat stress, and resource limits constrain this trend. Here, the authors show that within a year, increased early- and peak- season gre...

Happy to share our new #NatureComms paper, "Seasonal stabilization effects slowed the greening of the Northern Hemisphere over the last two decades" led by @uarizona.bsky.social PhD Candidate Wen Zhang w/ @trevorkeenan.bsky.social and others www.nature.com/articles/s41...

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Multiomics and cellular senescence profiling of aging human skeletal muscle uncovers Maraviroc as a senotherapeutic approach for sarcopenia - Nature Communications This study leverages single-nucleus multiomics to map cellular senescence atlas in aging human skeletal muscle and uncovers potential targets and senotherapeutics for treating age-associated sarcopeni...

New #NatureComms paper: Multiomics and cellular senescence profiling of aging human skeletal muscle uncovers Maraviroc as a senotherapeutic approach for sarcopenia. #Myoblue tinyurl.com/yzkepbyb

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In vivo self-renewal and expansion of quiescent stem cells from a non-human primate - Nature Communications The field of regenerative medicine would greatly benefit from the study of a non-human primate model. Here, the authors prospectively isolated two quiescent stem cell populations from the non-human pr...

New #NatureComms paper: In vivo self-renewal and expansion of quiescent stem cells from a non-human primate. #Myoblue #MuSC tinyurl.com/2mypcwdw

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