This study uses an ABE-based #sgRNA library to map over 1,000 functional #mutations that regulate PD-L1 and HLA-I expression, identifying SETD2_Y1666, which influences #ImmuneEvasion & anti-PD-1/PD-L1 therapy responses. @pku1898.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
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