Latest posts tagged with #siRNA on Bluesky
🧬 Can we switch off a gene to prevent heart attacks and strokes?
💊 In our video interview, #RNA interference pioneer Victor Kotelianski explains how #siRNA became a new class of medicines and led to a therapy now used worldwide to lower cholesterol.
youtu.be/5nGmE4R4HBM
Codexis and Pharmaceutical Partner Collaborate on siRNA Manufacturing Using Eco Synthesis Platform #United_States #Redwood_City #siRNA #Codexis #ECO_Synthesis
Frontier Biotech Enters Exclusive Licensing Deal with GSK for siRNA Therapeutics #USA #Nanjing #GSK #siRNA #Frontier_Biotech
Frontier Biotech and GSK Formulate Bold New Era in siRNA Therapeutics #USA #Nanjing #GSK #siRNA #Frontier_Biotech
Frontier Biotech Partners with GSK for Innovative Therapeutics Licensing #China #Nanjing #GSK #siRNA #Frontier_Biotech
Two years ago, #CRISPR pioneer Feng Zhang and former Illumina Alex Aravanis launched Moonwalk Biosciences to develop #epigenetic editing therapies. Now the company is shifting its focus to #siRNA therapies for #obesity. More details in my story for @endpts.com: endpoints.news/epigenetic-e...
New study suggests siRNA approach could reverse age-related cellular decline without triggering dedifferentiation or cancer-related pathways.
longevity.technology/news/study-s...
#longevity #biotech #siRNA #reprogramming #rejuvenation
🩸 China aprueba #FitusiránSódico (#Saifeiyin) para la profilaxis de hemofilia A y B graves, con o sin inhibidores.
📎 Más información: dengyuepharma.com
📧 info@dengyuemed.com
#Hemofilia #DeficienciaDelFactorVIII #DeficienciaDelFactorIX #SangradoRecurrente #ARNi #siRNA #DengYueMedicinasEnHongKong
Ribo Life Science Marks Major Milestone with Hong Kong Stock Exchange Listing #Hong_Kong #siRNA #Ribo_Life_Science
Ribo Life Science Marks New Era by Listing on Hong Kong Stock Exchange #Hong_Kong #siRNA #Ribo_Life_Science #Hong_Kong_Stock
In August's #EditorsChoice, Gianna Maggiore, @haozhulab.bsky.social & co showed strong clinical potential in reducing #HepatocellularCarcinoma by targeting the actin-binding protein anillin via #siRNA knockdown in #MouseModel.
⚡ doi.org/10.1242/dmm....
📰 doi.org/10.1242/dmm....
Rona Therapeutics Launches First Bi-valent siRNA for Heart Disease Risk Reduction #Australia #Santa_Barbara #Rona_Therapeutics #siRNA #RN5681
I just did a presentation on siRNA medicine, it uses short double stranded rna to bind to and trigger the degradation of mRNA transcript to silence genes and prevent certain proteins from being made. Research is ongoing for treatment of Alzheimer’s and ALS #sirna
🔬siRNA therapies are revolutionizing medicine!
Challenges: rapid degradation, poor biodistribution, cell barriers & off-target effects.Innovative delivery systems are the game-changer.
📍OTDC 2026|May25–26,Rome,Italy.
oligo-nucleotide.com
#siRNA #RNAresearch #Nanomedicine #Oligonucleotides #siRNA
🧬 Antiviral Oligonucleotides for Emerging Pathogens
🌍 Redefining the antiviral frontier!
Oligonucleotides bring speed, specificity, and innovation to fight emerging infectious threats.
📅 May 25–26, 2026 | 📍 Rome, Italy
🌐 oligo-nucleotide.com
#mRNAtherapeutics #OligoVaccine #siRNA #DNAbasedDrugs
Targeting clinical trials in metabolic dysfunction in 2026, gene-silencing approach seeks to reprogram diseased cells to a healthy state.
longevity.technology/news/junevit...
#longevity #investment #siRNA #biotech #reprogramming
Rona Therapeutics Unveils Promising Phase 1 Results for RN0361 at AHA 2025 #USA #New_Orleans #Rona_Therapeutics #RN0361 #siRNA
Remarkable, groundbreaking progress for cardiometabolic science and medicine!!! #FGF21R #GLP1 #APOC3 #ANGPTL3 #PCSK9 #mAb #siRNA #ASO #CRISPRCas9
Shoutout to ♥️ basic and clinical scientists moving this forward for our patients! @ahascience.bsky.social #AHA25 #PrevCards #Lipidology
#ADX324, a next-generation small interference (#siRNA) therapeutic for hereditary angioedema (#HAE), has received #OrphanDrug Designation from the US FDA and entered phase 3 development, with the first patient dosed in the #STOPHAE trial.
Read more: https://bit.ly/43hyVPt
#RareDisease #MedSky
Joined University of Gothenburg as a Principal Investigator (PI). With that I begin an independent journey in #RNAthereapeutics and #extracellularvesicles
#Exosomes
#Lipidnanopartivles
#RNA
#mRNA
#RNAi
#siRNA
Vial Launches Phase 1 Trial for Novel INHBE siRNA to Combat Obesity #United_States #San_Francisco #obesity #siRNA #VIAL-INHBE
I’m attending #ASHG2025 in Boston this week! Excited to connect with researchers and innovators in genetics, drug target identification, and clinical development. I’ll be here until Saturday — let’s meet and explore collaboration opportunities!
#Genomics #DrugDiscovery #RNAi #siRNA
Uncertainty‑Guided Model Selection Improves Biomolecule Predictions
Using TabPFN's inter‑quantile range to pick low‑uncertainty models improves siRNA knockdown predictions, beating simple averaging. The pre‑print was posted on 2 Oct 2025. getnews.me/uncertainty-guided-model... #tabpfn #siRNA
The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, LMU München @lmumuenchen.bsky.social , is NOW available 🔓 in the video portal of the TIB Hannover:
🔗 https://av.tib.eu/media/71537
#DrugDelivery #siRNA #BeilsteinTalks
The video 🎥 of the #BeilsteinTalk “Computational approaches in improving spermine-based RNA #nanocarriers" with Olivia Merkel, Ludwig-Maximilians-Universität Munich, is NOW available 🔓 in the video portal @TIB_AVPortal of the @tibhannover.
🔗 […]
[Original post on hessen.social]
At Arnatar, we’re pioneering next-gen #RNAMedicines to treat severe & underserved diseases. Backed by our DARGER™ Platform, we advance antisense & #siRNA therapeutics that both up and down-regulate gene expression with precision.
Explore our pipeline: https://www.arnatar.com/pipeline
Rona Therapeutics Files IND for Innovative RN3161 siRNA Targeting Obesity Treatment #USA #Santa_Barbara #Rona_Therapeutics #RN3161 #siRNA
Direct optogenetic activation of skeletal muscle offers an alternative to invasive electrical stimulation. Knapman et al. tested the ability of adeno-associated viral vectors (AAV9 and AAVMYO) to confer light sensitivity to upper airway muscles in a model of obstructive sleep apnea. The image shows robust opsin expression (orange) in axial sections from the anterior and middle regions of a rat tongue 3 weeks after intramuscular AAV9 delivery. Image credit: Fiona L. Knapman.
Check out the latest issue of #MolecularTherapy Methods & Clinical Development for reviews on #LNPs and #genetherapy redosing, plus research on #AAV manufacturing, #siRNA therapy, and #celltherapy. Read it here: http://dlvr.it/TN2q33
#MTMCD
This establishes that when you deliver siRNA matters just as much as what you deliver - a principle with broad applications across combination therapies.
Would love input from oncology and nanomedicine communities.
#siRNA #CancerResearch #GeneTherapy #CancerTherapy #BreastCancer #Medsky (7/8)
