Looking forward to working together in the future and further develop #StructuralPhylogenetics in viruses @spyroslytras.bsky.social
#StrPhy26 #StrPhy
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#strphy
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Brisbane night
Wrapping up an incredible final day at the APSPM meeting! Huge thanks to the organizers @cpuentelelievre.bsky.social @proteinmechanic.bsky.social Jordan Douglas and all the speakers for the brilliant talks and rich discussions. Beautiful Brisbane!
#StrPhy #StrPhy26 #StructuralPhylogenetics
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APSPM2026 - What can we learn from ancient protein history?
@joannamasel.bsky.social will open with her research tracing how the genetic code first evolved and the surprising origin of tryptophan.
@official-smbe.bsky.social
#StrPhy26 #StrPhy
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Talking about structure-based protein annotations in weid critters (or „Why we shouldn’t say ‘structural homolog’!”). Thanks for having me @strphy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics
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@StrPhy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics APSPM 2026 Meeting, Brisbane: The SMBE Australasian Protein Structural Phylogenetics Meeting
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@StrPhy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics APSPM 2026 Meeting, Brisbane: The SMBE Australasian Protein Structural Phylogenetics Meeting
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Amazing to see all the approaches to structural phylogenetics at APSPM 2026 Meeting, Brisbane: The SMBE Australasian Protein Structural Phylogenetics Meeting @StrPhy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics
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Linking to the APSPM 2026 Meeting going on right now in Brisbane: The SMBE Australasian Protein Structural Phylogenetics Meeting @StrPhy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics
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APSPM2026 - Today's session starts with @claudiaalcar.bsky.social
Charting the protein universe: Deep evolutionary signals in sequence structure space (remote).
She'll present her work on exploring how protein folds emerged and diversified over billions of years.
#StrPhy26 #StrPhy
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Looking forward to sharing this method as a hands-on workshop in the upcoming meeting
For a full list of workshop we have: biosig.lab.uq.edu.au/strphy26/wor...
#StrPhy26 #StrPhy #StructuralPhylogenetics #Evolution #Brisbane
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Like with the MBE work, DeepRoots introduces a new and much faster way to bootstrap. It achieves this by introducing "Embedding Jitter"—injecting Gaussian noise into the latent space to estimate branch support.
#Phylogenetics #StructuralBiology #Structome #Evolution #StructuralPhylogenetics #StrPhy
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The logic behind this is #EmergentLatentBiology #ELB & is now formalized in our new paper in Curr Op in #StructuralBiology arguing that transformers organize biophysics into a "substrate" where biology becomes easily-decodable. www.sciencedirect.com/science/arti...
#Strphy #StructuralPhylogenetics
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Enter Structome-DeepRoots which uses high-dimensional embeddings from protein language models to see evolutionary "roots" invisible to geometry alone. It was turned into a web app (still has a lot of bugs 😅). 🔗 biosig.lab.uq.edu.au/structome_de...
#StructuralBiology #StructuralPhylogenetics #StrPhy
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Protein structure is more conserved than sequence. Work in 2020 (MBE: academic.oup.com/mbe/article/...), showed 3D data unlocks deeper evolutionary signals. A thought was why not go higher than 3D? 🧵
#Phylogenetics #StructuralBiology #Structome #Evolution #StructuralPhylogenetics #StrPhy
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The program is now live. An excellent global lineup of speakers - AUS, NZ, Korea, India, Laos, UK, Switzerland, France, Finland, Germany, Hungary, Japan, Uruguay, Mexico and USA. Browse abstracts. Just 3 weeks left. Super excited.
#StrPhy26 #Science #Evolution #StrPhy #StructuralPhylogenetics
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An interesting way to look at encoded structural characters to build alignments and trees downstream. This takes structural phylogenetics one step further in the post-AlphaFold era.
#Evolution #Science #StrPhy
On Confidence Assessment in Structure-Aware Alignments
doi.org/10.1093/gbe/...
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Abstract submissions are open for #APSPM2026!
🗓️ Deadline: Nov 28, 2026
📍 Brisbane + online
🎓 Travel grants for students & ECRs
Join us to explore how protein structures and AI are reshaping evolutionary biology.
@official-smbe.bsky.social
#StrPhy26 #StrPhy
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Attending a fascinating talk by
Prof Begona Heras on “Structural insights into the function and inhibition of bacterial virulence proteins. “
Looking for overlaps with methods we are putting together in the Structural Phylogenetics space. #StrPhy #StructuralPhylogenetics @strphy.bsky.social
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We’ve set up a dedicated Bluesky space for structural phylogenetics: @strphy.bsky.social. Follow for community updates.
#StrPhy #StructuralPhylogenetics
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