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It is amazing that @dudinlab.bsky.social beautiful #ExM composition has been selected to highlight our #6mA work for the cover of @natgenet.nature.com. #Protists (and ichthyosporeans in particular) in the cover of NG must be quite unique!

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And also out, the short Research Briefings summarising our #6mA findings, with an honest explanation of the origins of this project (tldr: this was never planned, but a serendipitous branching point of another project): www.nature.com/articles/s41...

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Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.

Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

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Sequence-independent 6mA methyltransferases for epigenetic profiling and editing. #DNAmodification #6mA #Epigenetics #Genomics @cp-trendsgenetics.bsky.social
www.cell.com/trends/genet...

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Thrilled to share that the lab has been awarded a @wellcometrust.bsky.social Discovery Award to keep exploring the evolution of 6-methyladenine #6mA in Eukaryotes. We'll open postdoc (3️⃣) and tech (1️⃣) positions to start in 2026, please share with candidates or reach out if you’d like to join us.

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The #6mA reader YTHDF3 recruits ssDNA-specific #ALKBH1 demethylase to genomic DNA and allows it to remove 6mA from double-stranded DNA regions
Guang-Rong Yan, Xiao-Feng Gu and coworkers
www.embopress.org/doi/full/10....

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RNA methylation in retrotransposon control. #RNAmethylation #6mA #LTR #L1#ERV #RetrotransposonControl #RNAdecay #RNAstability #GenomeRegulation #CellularDifferentiation @cp-trendsgenetics.bsky.social‬
www.cell.com/trends/genet...

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