#AdvancedScience

Maja Klevanski

@majaklevanski.bsky.social

2 weeks ago

The gray planet symbolizes a cell that appears lifeless at first glance. Lectins, depicted as a UFO, illuminate and reveal its glycans, transforming it into a vibrant molecular landscape and highlighting the hidden complexity and biological significance of cellular nanoarchitecture.

Our Glyco-STORM paper is officially out in the 23 Feb 2026 issue of #AdvancedScience: doi.org/10.1002/advs....
Celebrating with the cover artwork🎉.
What looks gray and lifeless at first glance unfolds into complex molecular landscapes when revealed with lectin probes & super-resolution microscopy.

BIST-Barcelona Institute of Science and Technology

@bist.eu

3 weeks ago

Could a Mussel-Inspired Adhesive Patch Help Treat Brain Tumours?

Researchers at @icn2.bsky.social, @uab.cat & Bellvitge University Hospital develop an adhesive membrane able to kill up to 90% of cancer cells in lab models

📝 Published in #AdvancedScience
#BISTCommunity

👉 bist.eu/could-a-muss...

WIMI Biotech

@wimi-bio-tech.bsky.social

1 month ago

🚀 WIMI Biotech & SJTU breakthrough in Advanced Science!
We’ve bridged the gap from "natural discovery" to "AI-guided design" for crop engineering.
🧵1/4
Read more:
advanced.onlinelibrary.wiley.com/.../advs.202...
#WimiBiotech #SJTU #AdvancedScience #AgTech #PlantBiology #AI #SyntheticBiology

Paulina Strzyz

@paulinastrzyz.bsky.social

1 month ago

The Other Side of the Desk: Science Editors and Submissions The Academic Life newsletter by Christina Gessler, Ph.D.

Ever wondered what a scientific editor actually does? I recently shared my perspective on this in a written interview for the Academic Life Substack:
👇
shorturl.at/vqGxU

#CareersOutsideAcademia #ScientificEditing #AdvancedScience

Paulina Strzyz

@paulinastrzyz.bsky.social

1 month ago

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53 NUMB Ex3-containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells an...

New in #AdvancedScience @wileylifesci.bsky.social
Cells can export the tumor suppressor #p53 in #exosomes and share it with neighbors. The transferred p53 remains functional—activating protective programs in recipient cells.
In this way cells might collaborate to prevent cancer.
📄 shorturl.at/veeKj

Paulina Strzyz

@paulinastrzyz.bsky.social

1 month ago

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid-beta and phospho-Tau aggregation, neuronal hyperexcitab...

New in #AdvancedScience @wileylifesci.bsky.social
Human brain #organoids from #Alzheimer's patients now faithfully reproduce disease pathology. Even better: a new #autophagy drug candidate reverses the damage.
A step toward testing treatments in human tissue, not just mice
📃https://shorturl.at/HvAKn

Paulina Strzyz

@paulinastrzyz.bsky.social

2 months ago

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor-dependent transcriptional and translational mechanisms. VitD regulates ....

#VitaminD does more than support bones—it fine-tunes sense of #smell! New work in #AdvancedScience @wileylifesci.bsky.social shows vitamin D controls synaptic proteins in the olfactory bulb, using both gene regulation and #mTOR. Nutrition meets #neuroscience!
🔗 shorturl.at/3ubBn
#Olfaction

Paulina Strzyz

@paulinastrzyz.bsky.social

2 months ago

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane-anchored LC3 partitions into these condensates, suggesting that...

New research in #AdvancedScience @wileylifesci.bsky.social TBK1 phosphorylation drives optineurin to form filaments that phase separate with poly #ubiquitin and LC3, organizing cargo for selective #autophagy. New insight into autophagy and #neurodegeneration.
🔗 shorturl.at/HzkK8

Paulina Strzyz

@paulinastrzyz.bsky.social

3 months ago

The Importance of Being Imperfect: Structure and Function of Bacterial Amyloid Functional bacterial amyloids such as CsgA and FapC have been widely studied to understand the relationship between aggregation and function. The recently solved structure of FapC reveals a Greek-key...

New review in #AdvancedScience: #Amyloids aren’t just disease markers—in bacteria, they’re dynamic, functional protein assemblies with roles in biofilms, catalysis, and more. Ripe for #biomaterials innovation!
🔗 shorturl.at/wPAQb
#microbiology #SyntheticBiology @wileylifesci.bsky.social

Paulina Strzyz

@paulinastrzyz.bsky.social

3 months ago

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses Cryopreserved lung-humanized mice overcome the dependency to fresh tissues and permit head-to-head profiling of all four human common cold coronaviruses versus SARS-CoV-2 infection; the model validat...

New in #AdvancedScience: Dual-humanized mouse model with cryopreserved human lung tissue lets researchers study common cold #coronaviruses & #SARS-CoV-2 in a human-relevant way. Opens doors for testing #antivirals and exploring immune responses.
🔗 shorturl.at/CYJZU @wileylifesci.bsky.social

Maja Klevanski

@majaklevanski.bsky.social

3 months ago

Curious about the minute sugar landscape within our cells?🍭Discover it in our recent article in #AdvancedScience, where we map subcellular glycosylation using super-resolution microscopy.🔬

Paulina Strzyz

@paulinastrzyz.bsky.social

4 months ago

New in #AdvancedScience @wileylifesci.bsky.social : Zhang et al. reveal how ERK, PKA, YAP/TAZ & SHH signaling shape cortical radial glia fate—offering fresh insight into brain development and evolution. #Neuroscience #RadialGlia #BrainScience #BrainEvolution shorturl.at/Z0isZ

Paulina Strzyz

@paulinastrzyz.bsky.social

4 months ago

Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis This study shows that mammary branching morphogenesis is regulated by extracellular matrix (ECM) stress relaxation. Slow stress-relaxing matrices promote branching through focal adhesion signaling, c...

New work in #AdvancedScience Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis @ucsantabarbara.bsky.social #Morphogenesis #ECM #Biomaterials #TissueEngineering #CellBiology #Mechanobiology Read full OA article shorturl.at/RxQIh

Paulina Strzyz

@paulinastrzyz.bsky.social

4 months ago

Nanoscale Mapping of the Subcellular Glycosylation Landscape Using multiplexed super-resolution imaging with fluorophore-labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending ...

Glyco-STORM: Nanoscale Mapping of the Subcellular Glycosylation Landscape by @majaklevanski.bsky.social published in #AdvancedScience Read full OA article here: shorturl.at/4GvlM @wileylifesci.bsky.social

Paulina Strzyz

@paulinastrzyz.bsky.social

4 months ago

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...

🧬 Just published in Advanced Science: New work from @linkermannlab.bsky.social showing that secondary necrosis can occur without Gasdermin E. A clear step forward in decoding regulated necrosis. #CellDeath #SecondaryNecrosis #GSDME #CaspaseInhibition #AdvancedScience #EditorPick shorturl.at/ITJe6

KC👨‍🔬🌾🍄🇦🇺

@karchuntan.bsky.social

4 months ago

Our @theccdm.bsky.social @CurtinEand #advancedscience student @CarliaHerbst turn to present her research on protein-protein interactions in Parastagonospora nodorum 😎. @callumverdonk.bsky.social

KC👨‍🔬🌾🍄🇦🇺

@karchuntan.bsky.social

4 months ago

Our @CurtinEandA @theccdm.bsky.social #advancedscience student 👨‍🎓Keshara Thanthrige (right) presenting his research assessment on the development of selectable marker recycling♻️ in a fungal pathogen.

Well done mate! 👏
@ShotaMorikawa69 @callumverdonk.bsky.social

BIST-Barcelona Institute of Science and Technology

@bist.eu

5 months ago

An international team led by #BISTCommunity centre @iciq.org shows how molecular design can enhance copper-based solar devices.

This work could mark an important step toward more efficient, stable #solar devices using abundant materials.

Published in #AdvancedScience

➡️ bist.eu/new-organic-...

Andy

@andyjobbins.bsky.social

5 months ago

AI‐Assisted Drug Re‐Purposing for Human Liver Fibrosis A multi-agent AI (AI co-scientist) is used to repurpose drugs for liver fibrosis treatment and to guide their experimental characterization. The anti-fibrotic efficacy and toxicity of these drugs is ...

Do we already have the drugs we need for the diseases at hand and is #AI the key to finding these hidden gems?
A paper published in #AdvancedScience demonstrates that a "AI co-scientist" can guide the repurposing of drugs for #liverfibrosis.

advanced.onlinelibrary.wiley.com/doi/10.1002/...

icmabCSIC

@icmabcsic.bsky.social

6 months ago

New paper published in #AdvancedScience!

📌Microwave-Assisted Synthesis of Cu/Co-Based Nanoheterostructures for High-Efficiency Alcohol Oxidation

icmab.es/microwave-as...

📜Read the paper here: advanced.onlinelibrary.wiley.com/doi/10.1002/...

Raz Jelinek

@razjelinek-lab.bsky.social

6 months ago

🚨 New paper in #Advanced_Science!

We developed a photo-rechargeable supercapacitor powered by light through a novel light-sensitive electrolyte ⚡

📄 Read the full paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...

#AdvancedScience #EnergyStorage #Supercapacitor #SustainableEnergy

Virginia Giolito

@virginiagiolito.bsky.social

7 months ago

5/5
👏 A big thank you to all colleagues and collaborators who contributed to this journey. And of course funding agencies for their support.

#Metabolism #Acidosis #LipidUptake #CellStress #Cancer #Cardiovascular #AdvancedScience

icmabCSIC

@icmabcsic.bsky.social

9 months ago

New #ICMABresearch published in the journal #AdvancedScience!

📌A Universal Approach to Anchoring Chromophores onto Magnetic Scaffold for Achieving Easily Recyclable Heterogeneous Photocatalytic Systems

icmab.es/a-universal-...

📜Read the paper: advanced.onlinelibrary.wiley.com/doi/10.1002/...

Rice Neuroengineering Initiative

@riceneuro.bsky.social

11 months ago

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast-spiking interneurons ...

A recent study from @riceneuro.bsky.social Luan Lab in #AdvancedScience explores the neurophysiological effects of single #microinfarcts using an advanced platform that combines high-resolution imaging and #neuralrecordings.
Read more: bit.ly/3GkrOgg

Giulio Pergola

@giuliopergola.bsky.social

11 months ago

Altered Brain‐Behavior Association During Resting State is a Potential Psychosis Risk Marker The study detects a potential multimodal biomarker that can be promising for identifying early markers of psychosis. It shows a consistent brain-behavior association between a circuit of interconnect...

🧠🎉 New paper in #AdvancedScience! 👏
Giuseppe Stolfa, from #UNIBA, used a novel #graph-based approach to define meta-ROIs on resting-state #fMRI data from 1,200+ subjects. Prefrontal-striatal #connectivity is associated to executive function and altered in #psychosis, even without cognitive deficits

Giuseppe Ciccone

@giusciccone.bsky.social

1 year ago

Very happy to share the final version of our work, out in #AdvancedScience!

AZoAI

@azoai.bsky.social

1 year ago

Next-Gen AI Hardware Uses Spin Waves to Unlock Unmatched Computing Power Researchers developed an iono-magnonic reservoir computing device leveraging spin wave manipulation through ion-gating, achieving groundbreaking computational efficiency for AI systems.

Next-Gen AI Hardware Uses Spin Waves to Unlock Unmatched Computing Power 🌐💡📊 www.azoai.com/news/2025011... #AI #SpinWaves #ReservoirComputing #IonGating #AdvancedScience #Neuromorphic #Innovation #EnergyEfficiency #MagneticMaterials #Computing

Dr Peter Sherrell

@nanoin3d.bsky.social

1 year ago

Efficient Decoupled Electrolytic Water Splitting in Acid through Pseudocapacitive TiO2 A new path for water electrolysis is described, decoupled water electrolysis, by exploiting cheap, abundant, pseudocapacitive TiO2 nanoparticles in acidic conditions. This two-step water-splitting re...

This talk is based on our #AdvancedScience paper where we made an #acidic #electrolyser by decoupling the #OER and #HER reactions temporally.

With a #energy efficiency of 52.4% nearing the range (60-80%) for commercial electrolysers.

onlinelibrary.wiley.com/doi/full/10....

#chemsky #ozchem 🧪