#CellStress

The Physiological Society of Japan 日本生理学会

@physiologyjapan.bsky.social

3 hours ago

🧫Just published online in JPS❣️ (📖 Open Access!! 14 March 2026)
“Dynamic Regulation of TASK-1 Channels Under Cellular Stress”
— Yang Yu et al.
🔗 doi.org/10.1016/j.jp...
#IonChannels #CellStress #TASK1 #Electrophysiology #NowOnline #JPhysiolSci

Diabetologia

@diabetologiajnl.bsky.social

1 month ago

Transient ER stress cell-autonomously promotes beta cell cycling in mice - Diabetologia Aims/hypothesis Regenerating endogenous pancreatic beta cells is a potentially curative yet currently elusive strategy for diabetes therapy. Mimicking the microenvironment of the developing pancreas a...

A novel link between ER stress dynamics and beta cell proliferation: transient ER stress promotes beta cell proliferation in a cell-autonomous manner. #Diabetes #DiabetesResearch #CellStress #BetaCells link.springer.com/article/10.1... 🔓

Keystone Symposia

@keystonesymposia.bsky.social

3 months ago

Autophagy Meeting Promo YouTube video by KeystoneSymposia

Register by Dec. 4 for Autophagy: Mechanisms to Therapy and save $250!
🎥 Speaker highlights: youtu.be/cD93K4w5W1E
Register now: t.co/bo1X9Ojest

#KSAutophagy26 #AutophagyResearch #CellStress #LysosomalBiology t.co/S5gnxKNpn4

CECAD Cologne

@cecad.bsky.social

7 months ago

Beyond classic stress signalling: how mitochondrial stress softens the cell nucleus and alters cellular identity A University of Cologne research team has discovered that cells in high-energy-demanding tissues respond to mitochondrial dysfunction in a surprising way. Instead of shutting down, cells adjust their ...

What happens when #mitochondria fail in high-energy tissues? Cells adjust their metabolism and alter the mechanics of the nucleus! Read more on the discovery by Dr. Harshita Kaul from the Trifunovic Lab in Nature Metabolism.

➡️ uni.koeln/QZURH

#CellStress #NatureMetabolism @unicologne.bsky.social

Virginia Giolito

@virginiagiolito.bsky.social

7 months ago

5/5
👏 A big thank you to all colleagues and collaborators who contributed to this journey. And of course funding agencies for their support.

#Metabolism #Acidosis #LipidUptake #CellStress #Cancer #Cardiovascular #AdvancedScience

Chiosis Lab

@chiosislabmskcc.bsky.social

10 months ago

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation - Nature Communications Epichaperomes are chaperone assemblies that reorganize protein networks under stress. Here, authors reveal how HSP90 phosphorylation drives epichaperome formation, linking this process to cancer cell ...

To know more about this strange and intriguing case check out our work linked below (8/8)
#phosphorylation #epichaperome #cancer #conformation #cellstress
www.nature.com/articles/s41...

Chiosis Lab

@chiosislabmskcc.bsky.social

10 months ago

Heat Shock Protein 90 (HSP90) is a cellular chaperone protein ubiquitously present in human body and is responsible for folding other important proteins in the cell. However, it can exist either as Dr. Jekyll or Mr. Hyde depending on how stressed the cells are. (3) #cellstress #HSP90

Chiosis Lab

@chiosislabmskcc.bsky.social

10 months ago

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation - Nature Communications Epichaperomes are chaperone assemblies that reorganize protein networks under stress. Here, authors reveal how HSP90 phosphorylation drives epichaperome formation, linking this process to cancer cell ...

🧵Follow this thread by Dr. Tanaya Roychowdhury to learn about the intriguing case of #HSP90 - adapted from our recent publication in @natcomms.nature.com (1/8)

#cancer #phosphorylation #epichaperome #conformation #cellstress

www.nature.com/articles/s41...

American Aging Association

@americanaging.bsky.social

10 months ago

🔬 Meet Dr. Rebecca Taylor
Dr. Rebecca Taylor dives into how environmental perception activates the Unfolded Protein Response to modulate aging.
Catch her at #AGEAnnualMeeting2025!
🔗 bit.ly/4cJx8Gd
#UPR #CellStress #MolecularAging #LongevityScience #AGE2025 #Geroscience #AnchorAGEAlaska

Diabetologia

@diabetologiajnl.bsky.social

1 year ago

A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on beta cell apoptosis in a patient with Wolfram syndrome - Diabetologia Aims/hypothesis Wolfram syndrome 1 (WS1) is an inherited condition mainly manifesting in childhood-onset diabetes mellitus and progressive optic nerve atrophy. The causative gene, WFS1, encodes wolfra...

Exciting research uncovers new #disease mechanisms for #WolframSyndrome: #cellstress and #inflammation impair the #NonsenseMediatedDecay, resulting in the accumulation of aberrant WFS1 mRNA isoforms and #BetaCell #apoptosis tinyurl.com/3ytj5kf4 🔓 #Endocrinology