#Chimerism

Ernie Bornheimer

@erniebornheimer.bsky.social

3 weeks ago

The Bizarre Biological Case of Lydia Fairchild YouTube video by Today I Learned Science

youtube.com/shorts/8rjlG...

Not political at all, just interesting.

#genetics
#chimera
#chimerism
#DNA

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Cells & Development

@cellsdev.bsky.social

1 month ago

Fig. 1. What determines the anatomical setpoint of regenerative homeostasis? Planarian flatworms regenerate after amputation using a resident population of stem cells. This process reliably stops when the correct species-specific head shape is restored. The following thought experiment illustrates the profound knowledge gap in our understanding of the rules of morphogenesis despite ample information about genes required for neoblast differentiation. (A) Fragments from a round-head species result in a round-headed regenerate; (B) Fragments from a flat-head species result in flat-headed regenerates. (C) A chimera can be produced by irradiating one species (removing half of the stem cells) and receiving injections of donor neoblasts from a flat-head species. (D) When neoblasts from diverse species combine in the same body, and the head is amputated, what head shape will the regenerative process construct? Despite genomic and molecular-biological information on regeneration in multiple species, the field as yet has no models which make a prediction. This illustrates the importance of chimeras in identifying gaps in our understanding of the rules of emergent processes such as anatomical homeostasis and collective decision-making by cell groups.

✂️ the head of round-head worm => new round head formed.
✂️ the head of flat-head worm => new flat head formed.
What shape will it be if we ✂️ the head of a worm with 50:50 round + flat stem cells?
Check out this exciting review by @drmichaellevin.bsky.social lab!
#chimerism
doi.org/10.1016/j.cd...

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IndigoRaven

@indigoraving.bsky.social

1 month ago

The Case of Lydia Fairchild and Her Chimerism (2002) | Embryo Project Encyclopedia In 2002, after applying for government assistance in the state of Washington, Lydia Fairchild was told that her two children were not a genetic match with her and that therefore, biologically, she cou...

posted about this on twit in 2012 - still trips me out embryo.asu.edu/pages/case-l... woman with two sets of dna in her. #chimerism

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Devukdelta || Feliformfactor

@devukdelta.bsky.social

1 month ago

Chimeric Vernid Going up for Auction! (i just find these guys fun to design)
SB: 25$
link to crossposts will be in the reply
#vernid #anthro #furry #chimerism #design

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Katherine Stiles

@katherinestiles.org

2 months ago

Murder victim discovered to have two sets of DNA due to rare condition A woman's body has been found to consist of varying proportions of male and female cells because of an extremely rare form of chimerism

Murder victim discovered to have two sets of DNA due to rare condition
www.newscientist.com/article/2507... #medsky #dna #chimerism

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praying mantis

@gentlem.bsky.social

2 months ago

Woman discovers that her blood is genetically male, baffling the scientific community — Earth.com Doctors in Brazil found that a 35-year-old woman’s blood carried male chromosomes, even though her body looked entirely female.

apple.news/Aqku9wem3S6O...
#chimerism
#twins
#GovernmentsAreNotMedicalProviders
#blood-chimera

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praying mantis

@gentlem.bsky.social

3 months ago

www.sciencedirect.com:5037/science/arti...
This is an excellent overview & analysis of #chimerism.
Many fertility Tx’s involve increasing sperm, ovum, & zygotes for better odds of conception.
As fertility medicine advances & becomes more widespread, a logical inference would be more human chimeras.

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Journal of Bone Marrow Transplantation and Cellular Therapy

@jbmtct.bsky.social

3 months ago

Early monitoring of minimal residual disease and donor chimerism helps detect relapse risk sooner in children after stem cell transplant, enabling timely interventions that improve outcomes.
🆓Read the full article at doi.org/10.46765/267...

#leukemia #neoplasm #chimerism #pediatric #JBMTCT

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Crow Tooth

@crowtooth.bsky.social

3 months ago

🫂👐🫂TWINS🫂👐🫂

#bellingham #bellinghamtattooartist #bellinghamtattoo #pnwtattooartist #pnwtattoo #washingtontattoo #washingtontattooartist #lgbtqtattoo #transtattooartist #transtattoo #transart #genderdysphoria #chimera #chimerism #humanchimera #twins #ventart #conversiontherapyfucksyouup

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praying mantis

@gentlem.bsky.social

4 months ago

Natural human chimeras: A review The term chimera has been borrowed from Greek mythology and has a long history of use in biology and genetics. A chimera is an organism whose cells ar…

www.sciencedirect.com/science/arti...
@phyllisjsilver.bsky.social
Thx Phyllis!
Another fine example of why
#GovernmentIsNOTAMedicalProvider

I can include a host of other scientific resources around various conditions, both defined & undefined, of natural examples of gender ambiguity.
#chimerism

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Will House

@willhouse.bsky.social

5 months ago

Scientists Discover Woman Carrying TWO Sets of DNA YouTube video by Today I Learned Science

Okay have another installment of actual #BiologicalSex this time via a lite dose of #chimerism

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The Journal of Molecular Diagnostics

@jmdiagn.bsky.social

11 months ago

Engraftment and Measurable Residual Disease Monitoring after Hematopoietic Stem Cell Transplantation Chimerism testing supports the study of engraftment and measurable residual disease (MRD) in patients after allogeneic hematopoietic stem cell transplant. In chimerism MRD, relapse can be predicted by...

#LegacyContent: Engraftment and Measurable Residual Disease Monitoring after Hematopoietic Stem Cell Transplantation: Comparison of Two #Chimerism Test Strategies, #NextGenSeq versus a Combination of Short-Tandem Repeats and Quantitative PCR

#OpenArchive: www.jmdjournal.org/article/S152...

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