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#CopyNumberVariation

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Posts tagged #CopyNumberVariation

Copy Number Variation: A Substrate for Plant Adaptation and Stress Response in Arabidopsis
Abraham, L., de Meaux, J. et al.
Paper
Details
#CopyNumberVariation #ArabidopsisGenetics #PlantAdaptationStressResponse

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Benchmarking scRNA-seq #CopyNumberVariation callers

6 methods
InferCNV
CONICSmat
CaSpER
copyKAT
Numbat
SCEVAN
mapped to 100 kB bins

Performance on Euploid vs Aneuploid/Tumor datasets

Differential sensitivity/specificity to gain, base, or loss

bioRxiv 2024
www.biorxiv.org/content/10.1...

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Tumor-like properties of #SmoothMuscleCell progenies in #Atherosclersis🤠

SMC progenies exhibit
1⃣ #DNADamage #CopyNumberVariation
2⃣Activated Cancer-like signals
3⃣Stem-like growth
Clonality; Non-senescence

SMC KRasG12D transgene ⬆️atherogenesis!
#CircAHA 2024
www.ahajournals.org/doi/abs/10.1...

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STmut
Inferring+Visualizing #SomaticMutation #CopyNumberVariation Germline SNP/#AllelicImbalance in Tumor #SpatialTranscriptomics

#SomaticMutation SNP CNV
sequencing-based ST needed

#GenomeBiology 2023
genomebiology.biomedcentral.com/articles/10....

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