This discovery suggests BRCA2 proteins can evolve different structures while still protecting genome stability. It reveals new insights into how DNA repair systems evolve across species.
#Evolution #GenomeBiology
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#GenomeBiology
Latest posts tagged with #GenomeBiology on Bluesky
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Posts tagged #GenomeBiology
#WIMMReads
🧪 From the Thomas Milne, Robert Beagrie and James Davies Groups: FACT is identified as a key regulator of 3D genome organisation, helping preserve promoter topology and large scale chromatin structure.
Read more👇
#GenomeBiology #Chromatin #WIMM @rdm.ox.ac.uk @medsci.ox.ac.uk #AcademicSky
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Pangenomic structural variant patterns reflect evolutionary diversification in Brassica napus. #StructuralVariants #Pangenomes #BrasicaNapusGenome #PlantGenomics #Bioinformatics #GenomeBiology 🧪🧬 🖥️
link.springer.com/article/10.1...
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HGMT: a database of human gut microbiota for tumors and immunotherapy response. #GutMicrobiota #TumorSample #Metagenomics #ImmunotherapyTreated #GenomeBiology 🧪🧬 🖥️
link.springer.com/article/10.1...
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Long-read structural variant discovery and targeted short read genotyping enables population scale characterization of structural variation in rhesus macaques. #SVs #RhesusMacaqueGenomes #LonngRead #Sequencing #Genomics #Bioinformatics #GenomeBiology 🧪🧬 🖥️
link.springer.com/article/10.1...
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Evaluation of false positive and false negative errors in targeted next generation sequencing. #TargetNGS #Sequencing #FalsePositives #FalseNegatives #Genomics #Bioinformatics #GenomeBiology
link.springer.com/article/10.1...
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Novel multiplex family-wide PCR and Nanopore sequencing of amplicons (FP-NSA) approach for surveillance of influenza- and coronaviruses in humans and animals. #Nanopore #AmpliconSequencing #VirusSurveillance #Coronaviruses #Influenza #GenomeBiology 🧪🧬
genomemedicine.biomedcentral.com/articles/10....
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Insights, opportunities, and challenges provided by large cell atlases. #CellAtlases #Bioinformatics #Genomics #GenomeBiology 🧪🧬 🖥️
genomebiology.biomedcentral.com/articles/10....
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Cell Decoder: decoding cell identity with multi-scale explainable deep learning. #SingleCellOmics #CellCharacterization #GenomeBiology 🧪🧬 🖥️
genomebiology.biomedcentral.com/articles/10....
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Unlocking the regulatory code of RNA: launching the Human RNome Project. #RNA #RNAregulation #RNomeProject #GenomeBiology 🧪🧬 🖥️
genomebiology.biomedcentral.com/articles/10....
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🧬We had a great time at the Genome Biology Program Retreat'25!
Big thanks to the organisers for such an inspiring and fun event 👏
Congrats to @miemonti.bsky.social for being part of the organising team and to @oguzhanbegik.bsky.social for giving a fantastic talk! 🎤✨
#GenomeBiology #CRG #NovoaLab
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New @irbbarcelona.org study shows that the efficiency of the Nonsense-Mediated mRNA Decay pathway—a key genetic quality control mechanism—varies across human tissues & individuals
Study in #GenomeBiology by @fransupek.bsky.social & @guillepalou.bsky.social
#BISTCommunity
➡️ bist.eu/a-key-geneti...
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Our latest paper, just out in #GenomeBiology: "GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density". @chopresearch.bsky.social @penngenetics.bsky.social
genomebiology.biomedcentral.com/articles/10....
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Deciphering the sequence basis and application of transcriptional initiation regulation in plant genomes through deep learning. #TranscriptionalInitiation #TranscriptionRegulation #PlantGenomes #DeepLearning #Genomics #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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A comprehensive benchmarking of adaptive sampling tools for nanopore sequencing. #Nanopore #Sequencing #AdaptiveSampling #Benchmarking #GenomeBiology #Bioinformatics #Genomics @nanoporetech.com 🧬 🖥️
genomebiology.biomedcentral.com/articles/10....
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ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Predicting the structural impact of human alternative splicing. #AlternativeSplicing #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Systematic benchmarking of computational methods to identify spatially variable genes. #SpatialTranscriptomics #MethodsBenchmarking #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Genomics will forever reshape forensic science and criminal justice. #Genomics #Forensics #GenomeBiology #Comment
genomebiology.biomedcentral.com/articles/10....
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Instead of focusing on which exact genes were gained or to avoid over-interpreting the ancestral reconstruction of our sets, we analysed the enriched GO terms and categories of pathways gained at these nodes. We found interesting specificity here
#genomebiology
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MAGdb: a comprehensive high quality MAGs repository for exploring microbial metagenome-assemble genomes. #MAGs #Metagenomics #MetagenomeAssembly #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Diverse short tandem repeat sequences influence gene regulation in human populations. #ShortTandemRepeats #GeneRegulation #HumanGenetics #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Bacillus drives functional states in synthetic plant root bacterial communities
#GenomeBiology by @gijsselten.bsky.social and @dejongepmi.bsky.social
genomebiology.biomedcentral.com/articles/10....
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Our study in #GenomeBiology reveals a new chemoreceptor family sensing phosphorylated C3 compounds. Found mainly in phytobacteria, it guides bacteria toward stressed plants. @krelllaboratory.bsky.social @blastmeetings.bsky.social @csicdivulga.bsky.social @csic.es
rdcu.be/eC7ZZ
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TRsv: simultaneous detection of tandem repeat variations, structural variations, and short indels using long read sequencing data. #LongReads #Sequencing #SVs #TRs #CNVs #Indels #Bioinformatics #Sequencing #GenomeBiology 🧬 🖥️
genomebiology.biomedcentral.com/articles/10....
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Highly accurate prophage island detection with PIDE. #ProphageDetection #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. #scDNAseq #CellPhylogeny #SNV #Indels #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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Enhancing transcriptome expression quantification through accurate assignment of long RNA sequencing reads with TranSigner. #Transcriptomics #LongReads #Sequencing #Bioinformatics #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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FedscGen: privacy-preserving federated batch effect correction of single-cell RNA sequencing data. #scRNAseq #BatchEffectCorrection #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
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TRFill: synergistic use of HiFi and Hi-C sequencing enables accurate assembly of tandem repeats for population-level analysis. #HiFi #HiC #Sequencing #Genomics #Assembly #TandemRepeats #GapClosing #GenomeBiology
@pacbio.bsky.social
genomebiology.biomedcentral.com/articles/10....
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